Yıl: 2022 Cilt: 37 Sayı: 3 Sayfa Aralığı: 220 - 225 Metin Dili: İngilizce DOI: 10.4274/MMJ.galenos.2022.540 İndeks Tarihi: 24-10-2022

Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes

Öz:
Objective: The risk factors for myocardial infarction (MI) can be separated into three general categories: non-modifiable factors, modifiable risk factors, and lifestyle. This study aimed to investigate whether or not there was any effect of cardiac wall thickness and coronary artery obstructions on acute MI. Methods: In this retrospective study of histopathological examinations of autopsies, two groups were formed. The first contained 28 cases diagnosed with acute MI and the second 28 cases with no heart pathology and the cause of death was reasons other than heart disease. The subjects in the two groups were similar in age, height, weight, and body mass index. The groups were compared in terms of the left and right ventricular wall thicknesses and the degree of obstruction of the right, left, anterior descending, and circumflex coronary arteries. Results: The mean left ventricular wall thickness was 1.461±0.2767 cm in the acute MI group and 1.386±0.2460 cm in the control group, with no statistically significant difference found between the two groups (p=0.289). A statistically significant difference in the degree of obstruction of the coronary arteries was found between the groups. Conclusions: Although the mean cardiac wall thickness was greater in the acute MI cases, no statistically significant difference was found between the two groups.
Anahtar Kelime:

Akut Miyokard Enfarktüsü Sonucu Ölenler ile Başka Nedenlerle Ölenler Arasında Kalp Duvar Kalınlıkları ve Koroner Arter Tıkanıklıklarının Karşılaştırılması

Öz:
maç: Akut miyokard enfarktüsünde (MI) risk faktörleri 3 kategoriye ayrılır. Değiştirilemeyen risk faktörleri, değiştirilebilir risk faktörleri ve yaşam tarzı ile ortaya çıkabilen risk faktörleridir. Bu çalışmada kalbin duvar kalınlıkları ve koroner arter tıkanıklıklarının akut MI üzerinde bir etkisinin olup olmadığı araştırılmıştır. Yöntemler: Retrospektif olarak yapılan çalışmada otopsilerin patolojik incelemesinde akut MI tanısı almış 28 olgu ile ölüm nedeni kalp hastalığı olmayan ve kalp patolojisi tespit edilmeyen 28 olgu seçildi. İki grup oluşturuldu. Ağırlık, boy, vücut kitle indeksi ve yaş iki grup için de yakın olacak şekilde yapıldı. Sol ve sağ ventrikül duvar kalınlıkları ve sirkumfleks, ön inen, sağ ve sol koroner damaraların tıkanıklık dereceleri karşılaştırıldı. Bulgular: Sol ventrikül duvar kalınlığı akut MI grubunda ortalama 1,461±0,2767, kontrol grubunda ise 1,386±0,2460 olup istatistiksel olarak anlamlı değildi (p=0,289). Koroner arter tıkanıklıklarının derecelerinin de iki grup arasında farklı idi ve bu farkta istatistiksel olarak anlamlıydı. Sonuçlar: Kalbin duvar kalınlıkları ortalamaları, akut MI olgularında daha yüksek olsa da gruplar arasında anlamlı istatistiksel fark saptanmamıştır.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction. J Am Coll Cardiol. 2018;72:2231-64.
  • 2. Boateng S, Sanborn T. Acute Myocardial Infarction. Dis Mon. 2013;59:83-96.
  • 3. Maron BJ, Maron MS. Hypertrophic cardiomyopathy. Lancet. 2013;381:242-55.
  • 4. Maron BJ, Ommen SR, Semsarian C, Spirito P, Olivotto I, Maron MS. Hypertrophic cardiomyopathy: present and future, with translation into contemporary cardiovascular medicine. J Am Coll Cardiol. 2014;64:83-99.
  • 5. Maron BJ. Hypertrophic cardiomyopathy: a systematic review. JAMA. 2002;287:1308-20.
  • 6. Maron BJ. Hypertrophic cardiomyopathy: an important global disease. Am J Med. 2004;116:63-5.
  • 7. Cecchi F, Olivotto I, Gistri R, Lorenzoni R, Chiriatti G, Camici PG. Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy. N Engl J Med. 2003;349:1027-35.
  • 8. Panza JA, Maris TJ, Maron BJ. Development and determinants of dynamic obstruction to left ventricular outflow in young patients with hypertrophic cardiomyopathy. Circulation. 1992;85:1398- 405.
  • 9. Panza JA, Petrone RK, Fananapazir L, Maron BJ. Utility of continuous wave Doppler echocardiography in the noninvasive assessment of left ventricular outflow tract pressure gradient in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol. 1992;19:91-9.
  • 10. Geske JB, Sorajja P, Nishimura RA, Ommen SR. Evaluation of left ventricular filling pressures by Doppler echocardiography in patients with hypertrophic cardiomyopathy: correlation with direct left atrial pressure measurement at cardiac catheterization. Circulation. 2007;116:2702-8.
  • 11. Maron MS, Olivotto I, Maron BJ, et al. The case for myocardial ischemia in hypertrophic cardiomyopathy. J Am Coll Cardiol. 2009;54:866-75.
  • 12. Gori F, Basso C, Thiene G. Myocardial infarction in a patient with hypertrophic cardiomyopathy. N Engl J Med. 2000;342:593-4.
  • 13. Waller BF, Maron BJ, Epstein SE, Roberts WC. Transmural myocardial infarction in hypertrophic cardiomyopathy: a cause of conversion from left ventricular asymmetry to symmetry and from normal-sized to dilated left ventricular cavity. Chest. 1981;79:461-5.
  • 14. Maron BJ, Epstein SE, Roberts WC. Hypertrophic cardiomyopathy and transmural myocardial infarction without significant atherosclerosis of the extramural coronary arteries. Am J Cardiol. 1979;43:1086-102.
  • 15. Olivotto I, Cecchi F, Gistri R, et al. Relevance of coronary microvascular flow impairment to long-term remodeling and systolic dysfunction in hypertrophic cardiomyopathy. J Am Coll Cardiol. 2006;47:1043-8.
  • 16. Ismail TF, Hsu LY, Greve AM, et al. Coronary microvascular ischemia in hypertrophic cardiomyopathy - a pixel-wise quantitative cardiovascular magnetic resonance perfusion study. J Cardiovasc Magn Reson. 2014;16:49.
  • 17. Cokkinos DV, Krajcer Z, Leachman RD. Coronary artery disease in hypertrophic cardiomyopathy. Am J Cardiol. 1985;55:1437-8.
  • 18. Stewart S, Schreiner B. Coexisting idiopathic hypertrophic subaortic stenosis and coronary artery disease. Clinical implication and operative management. J Thorac Cardiovasc Surg. 1981;82:278-80.
  • 19. Harjai KJ, Cheirif J, Murgo JP. Ischemia and atherosclerotic coronary artery disease in patients with hypertrophic cardiomyopathy: a review of incidence, pathophysiological mechanisms, clinical implications and management strategies. Coron Artery Dis. 1996;7:183-7.
  • 20. Walston A 2nd, Behar VS. Spectrum of coronary artery disease in idiopathic hypertrophic subaortic stenosis. Am J Cardiol. 1976;38:12-6.
  • 21. Cui L, Suo Y, Zhao Y, Li G, Liu T. Mid-Ventricular Obstructive Hypertrophic Cardiomyopathy and Apical Aneurysm Mimicking Acute ST-Elevation Myocardial Infarction. Ann Noninvasive Electrocardiol. 2016;21:98-101.
  • 22. Patanè S, Marte F, Di Bella G, Chiribiri A. Acute myocardial infarction with diminutive right coronary artery and obstructive hypertrophic cardiomyopathy without significant coronary stenoses. Int J Cardiol. 2009;135:e73-5.
  • 23. Gupta T, Harikrishnan P, Kolte D, et al. Outcomes of Acute Myocardial Infarction in Patients with Hypertrophic Cardiomyopathy. Am J Med. 2015;128:879-87.
  • 24. Onat A, Dursunoğlu D, Kahraman G, et al. Türk Erişkinlerinde Ölüm ve Koroner Olaylar: TEKHARF Çalışması Kohortunun 5-yıllık Takibi. Türk Kardiyol Dern Arş. 1996;24:8-15.
APA ALTIN I, ORUÇ M, Celbiş O, Samdanci E (2022). Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. , 220 - 225. 10.4274/MMJ.galenos.2022.540
Chicago ALTIN ISMAIL,ORUÇ MUCAHIT,Celbiş Osman,Samdanci Emine Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. (2022): 220 - 225. 10.4274/MMJ.galenos.2022.540
MLA ALTIN ISMAIL,ORUÇ MUCAHIT,Celbiş Osman,Samdanci Emine Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. , 2022, ss.220 - 225. 10.4274/MMJ.galenos.2022.540
AMA ALTIN I,ORUÇ M,Celbiş O,Samdanci E Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. . 2022; 220 - 225. 10.4274/MMJ.galenos.2022.540
Vancouver ALTIN I,ORUÇ M,Celbiş O,Samdanci E Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. . 2022; 220 - 225. 10.4274/MMJ.galenos.2022.540
IEEE ALTIN I,ORUÇ M,Celbiş O,Samdanci E "Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes." , ss.220 - 225, 2022. 10.4274/MMJ.galenos.2022.540
ISNAD ALTIN, ISMAIL vd. "Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes". (2022), 220-225. https://doi.org/10.4274/MMJ.galenos.2022.540
APA ALTIN I, ORUÇ M, Celbiş O, Samdanci E (2022). Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. Medeniyet Medical Journal, 37(3), 220 - 225. 10.4274/MMJ.galenos.2022.540
Chicago ALTIN ISMAIL,ORUÇ MUCAHIT,Celbiş Osman,Samdanci Emine Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. Medeniyet Medical Journal 37, no.3 (2022): 220 - 225. 10.4274/MMJ.galenos.2022.540
MLA ALTIN ISMAIL,ORUÇ MUCAHIT,Celbiş Osman,Samdanci Emine Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. Medeniyet Medical Journal, vol.37, no.3, 2022, ss.220 - 225. 10.4274/MMJ.galenos.2022.540
AMA ALTIN I,ORUÇ M,Celbiş O,Samdanci E Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. Medeniyet Medical Journal. 2022; 37(3): 220 - 225. 10.4274/MMJ.galenos.2022.540
Vancouver ALTIN I,ORUÇ M,Celbiş O,Samdanci E Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes. Medeniyet Medical Journal. 2022; 37(3): 220 - 225. 10.4274/MMJ.galenos.2022.540
IEEE ALTIN I,ORUÇ M,Celbiş O,Samdanci E "Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes." Medeniyet Medical Journal, 37, ss.220 - 225, 2022. 10.4274/MMJ.galenos.2022.540
ISNAD ALTIN, ISMAIL vd. "Comparison of Cardiac Wall Thicknesses and Coronary Artery Obstructions Between Deaths Resulting From Acute Myocardial Infarction and Deaths From Other Causes". Medeniyet Medical Journal 37/3 (2022), 220-225. https://doi.org/10.4274/MMJ.galenos.2022.540