Yıl: 2022 Cilt: 33 Sayı: 9 Sayfa Aralığı: 803 - 807 Metin Dili: İngilizce DOI: 10.5152/tjg.2022.21944 İndeks Tarihi: 26-10-2022

Clinical Features and Outcomes of Gallbladder Polyps in Children

Öz:
Background: Gallbladder polyps are rare lesions protruding into the gallbladder lumen with variable clinical presentation. No standard treatment algorithm has been developed for pediatric gallbladders, and the malignant potential of the gallbladder is not clear in children. Therefore, a retrospective study was performed to evaluate the clinical features and treatment options of gallbladder polyps in children. Methods: Between 2014 and 2020, children diagnosed with gallbladder polyps were evaluated for age, gender, clinical features, results of follow-up with ultrasound findings, and treatment options retrospectively. Results: The records of 15 patients with a mean age of 13.2 years (2-20 years) were included. The male: female ratio was 7 : 8. Gallbladder polyps was detected incidentally in 73.3% (n = 11) of the patients. Four (20%) of the patients were symptomatic (26.7%) and complained about abdominal pain. Laboratory tests were normal except in 3 patients who showed slightly increased liver function tests. Two of the patients had 3 polyps on admission. The polyps were 2-10 mm in size. The size of the polyp increased in 5 patients (33.3%) and disappeared in 4 patients (26.6%) in follow-up ultrasound examinations. Five of the patients underwent cholecystectomy and 1 of them was scheduled for surgery. Five of the asymptomatic patients who have polyps less than 10 mm in size are still on follow-up. In patients with cholecystectomy, the histopathology of gallbladders revealed cholesterol polyps (n = 2) and hyperplastic polyps (n = 2). One of the patients with cholecystectomy showed no polyps in histopathological evaluation. Conclusion: Despite the lack of a standardized algorithm, our data suggested that multiple polyps, polyps with increased in size or greater than 10 mm, and the presence of symptoms might require cholecystectomy in children. Asymptomatic patients with small-sized polyps can be identified using ultrasound, and the polyps may disappear during the subsequent follow-up.
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  • 1. Demirbaş F, Çaltepe G, Comba A, et al. Gallbladder Polyps: rare lesions in childhood. JPGN. 2019;68:89-93.
  • 2. Ballouhey Q, Binet A, Varlet F, et al. Management of polypoid gallbladder lesions in children: A multicenter study. Eur J Pediatr Surg. 2018;28(1):6-11. [CrossRef]
  • 3. Jørgensen T, Jensen KH. Polyps in the gallbladder. A prevalence study. Scand J Gastroenterol. 1990;25(3):281-286. [CrossRef]
  • 4. Christensen AH, Ishak KG. Bening tumors and pseudotumors of the gallbladder. Report of 180 cases. Arch Pathol. 1970;90(5): 423-432.
  • 5. Elmasry M, Lindop D, Dunne DF, Malik H, Poston GJ, Fenwick SW. The risk of malignancy in ultrasound detected gallbladder polyps: a systematic review. Int J Surg. 2016;33(A):28-35. [CrossRef]
  • 6. Wiles R, Thoeni RF, Barbu ST, et al. Management and follow-up of gallbladder polyps : joint guidelines between the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), European Association for Endoscopic Surgery and other Interventional Techniques (EAES), International Society of Digestive Surgery - European Federation (EFISDS) and European Society of Gastrointestinal Endoscopy (ESGE). Eur Radiol. 2017;27(9):3856-3866. [CrossRef]
  • 7. Beck PL, Shaffer EA, Gall DG, Sherman PM. The natural history and significance of ultrasonographically defined polypoid lesions of the gallbladder in children. J Pediatr Surg. 2007;42(11):1907-1912. [CrossRef]
  • 8. Stringer MD, Ceylan H, Ward K, Wyatt JI. Gallbladder polyps in children– classification and management. J Pediatr Surg. 2003;38(11): 1680-1684. [CrossRef]
  • 9. Yang HL, Sun YG, Wang Z. Polypoid lesions of the gallbladder: diagnosis and indications for surgery. Br J Surg. 1992;79(3):227 -229. [CrossRef]
  • 10. Lee KF, Wong J, Li JC, Lai PBS. Polypoid lesions of gallbladder. Am J Surg. 2014;188:186-190.
  • 11. Koga A, Watanabe K, Fukuyama T, Takiguchi S, Nakayama F. Diagnosis and operative indications for polypoid lesions of the gallbladder. Arch Surg. 1988;123(1):26-29. [CrossRef]
  • 12. Csendes A, Burgos AM, Csendes P, Smok G, Rojas J. Late followup of polypoid lesions of the gallbladder smaller than 10 mm. Ann Surg. 2001;234(5):657-660. [CrossRef]
  • 13. Jeanty P, Ammann W, Cooperberg P, et al. Mobile intraluminal masses of the gallbladder. J Ultrasound Med. 1983;2(2):65-71. [CrossRef]
  • 14. Adsay V, Jang KT, Roa JC, et al. Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥ 1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases. Am J Surg Pathol. 2012;36(9):1279-1301. [CrossRef]
APA orkhan f, OGUZ B, Soyer T, Boybeyi Turer O, HALILOGLU M, Tanyel F (2022). Clinical Features and Outcomes of Gallbladder Polyps in Children. , 803 - 807. 10.5152/tjg.2022.21944
Chicago orkhan farzaliyev,OGUZ BERNA,Soyer Tutku,Boybeyi Turer Ozlem,HALILOGLU MITHAT,Tanyel Feridun Clinical Features and Outcomes of Gallbladder Polyps in Children. (2022): 803 - 807. 10.5152/tjg.2022.21944
MLA orkhan farzaliyev,OGUZ BERNA,Soyer Tutku,Boybeyi Turer Ozlem,HALILOGLU MITHAT,Tanyel Feridun Clinical Features and Outcomes of Gallbladder Polyps in Children. , 2022, ss.803 - 807. 10.5152/tjg.2022.21944
AMA orkhan f,OGUZ B,Soyer T,Boybeyi Turer O,HALILOGLU M,Tanyel F Clinical Features and Outcomes of Gallbladder Polyps in Children. . 2022; 803 - 807. 10.5152/tjg.2022.21944
Vancouver orkhan f,OGUZ B,Soyer T,Boybeyi Turer O,HALILOGLU M,Tanyel F Clinical Features and Outcomes of Gallbladder Polyps in Children. . 2022; 803 - 807. 10.5152/tjg.2022.21944
IEEE orkhan f,OGUZ B,Soyer T,Boybeyi Turer O,HALILOGLU M,Tanyel F "Clinical Features and Outcomes of Gallbladder Polyps in Children." , ss.803 - 807, 2022. 10.5152/tjg.2022.21944
ISNAD orkhan, farzaliyev vd. "Clinical Features and Outcomes of Gallbladder Polyps in Children". (2022), 803-807. https://doi.org/10.5152/tjg.2022.21944
APA orkhan f, OGUZ B, Soyer T, Boybeyi Turer O, HALILOGLU M, Tanyel F (2022). Clinical Features and Outcomes of Gallbladder Polyps in Children. Turkish Journal of Gastroenterology, 33(9), 803 - 807. 10.5152/tjg.2022.21944
Chicago orkhan farzaliyev,OGUZ BERNA,Soyer Tutku,Boybeyi Turer Ozlem,HALILOGLU MITHAT,Tanyel Feridun Clinical Features and Outcomes of Gallbladder Polyps in Children. Turkish Journal of Gastroenterology 33, no.9 (2022): 803 - 807. 10.5152/tjg.2022.21944
MLA orkhan farzaliyev,OGUZ BERNA,Soyer Tutku,Boybeyi Turer Ozlem,HALILOGLU MITHAT,Tanyel Feridun Clinical Features and Outcomes of Gallbladder Polyps in Children. Turkish Journal of Gastroenterology, vol.33, no.9, 2022, ss.803 - 807. 10.5152/tjg.2022.21944
AMA orkhan f,OGUZ B,Soyer T,Boybeyi Turer O,HALILOGLU M,Tanyel F Clinical Features and Outcomes of Gallbladder Polyps in Children. Turkish Journal of Gastroenterology. 2022; 33(9): 803 - 807. 10.5152/tjg.2022.21944
Vancouver orkhan f,OGUZ B,Soyer T,Boybeyi Turer O,HALILOGLU M,Tanyel F Clinical Features and Outcomes of Gallbladder Polyps in Children. Turkish Journal of Gastroenterology. 2022; 33(9): 803 - 807. 10.5152/tjg.2022.21944
IEEE orkhan f,OGUZ B,Soyer T,Boybeyi Turer O,HALILOGLU M,Tanyel F "Clinical Features and Outcomes of Gallbladder Polyps in Children." Turkish Journal of Gastroenterology, 33, ss.803 - 807, 2022. 10.5152/tjg.2022.21944
ISNAD orkhan, farzaliyev vd. "Clinical Features and Outcomes of Gallbladder Polyps in Children". Turkish Journal of Gastroenterology 33/9 (2022), 803-807. https://doi.org/10.5152/tjg.2022.21944