Yıl: 2022 Cilt: 23 Sayı: 3 Sayfa Aralığı: 355 - 360 Metin Dili: İngilizce DOI: 10.4274/meandros.galenos.2022.26986 İndeks Tarihi: 27-10-2022

Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience

Öz:
Objective: We evaluated the demographic and clinical characteristics, risk factors, involved vasculature, and prognosis in cerebral venous thrombosis. Materials and Methods: We included 53 patients with cerebral venous thrombosis (CVT) who were followed up in our neurology inpatient clinic and neurology intensive care unit in the study. The demographic and clinical characteristics on admission, risk factors, results of laboratory tests and neuroimaging studies, treatment, outcomes at discharge, and 6th-month follow-up were reviewed. Results: The mean age of the patients was 44.1±13.7 (19-71) years. Thirty-one (58.4%) of the patients were female. The most frequent symptom was headache (69.8%). Puerperium and malignancy were the most common risk factors for patients under 45 years of age; whereas anemia and malignancy were the most common risk factors for patients over 45 years of age. The most common localization of CVT was found to be the transverse sinus (69.8%). The modified Rankin scale (mRS) scores at discharge were 0 for 47 patients (88.6%), 1 for 4 patients (7.5%) and 4 for 2 patients. In the 6th-month follow-up, 48 (90.5 %) of the patients had an mRS score of 0 with normal neurological examination. Conclusion: Our study, representing the experience of a single tertiary referral center, showed that CVT mostly affected women of reproductive ages. More than 90% of patients in our study had an mRS score of 0 at the 6th-month follow- up. The results of our study suggest that early diagnosis of CVT with advanced neuroimaging techniques recently has improved the outcomes and reduced the disability.
Anahtar Kelime:

Serebral Ven Trombozunda Risk Faktörleri, Klinik Özellikler ve Prognozun Değerlendirilmesi: Üçüncü Basamak Tek Merkez Deneyimi

Öz:
Amaç: Bu çalışmada serebral ven trombozunun (SVT) demografik ve klinik özelliklerinin, risk faktörlerinin, tutulan damar sisteminin ve prognozun değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Nöroloji polikliniğimizde ve nöroloji yoğun bakım ünitemizde takip edilen SVT’li 53 hasta çalışmaya dahil edildi. Başvurudaki demografik ve klinik özellikler, risk faktörleri, laboratuvar testleri ve beyin görüntüleme çalışmalarının sonuçları, tedavi, taburculuk sonuçları ve 6. ay takipleri gözden geçirildi. Bulgular: Hastaların yaş ortalaması 44,1±13,7 (19-71) yıl idi. Hastaların 31’i (%58,4) kadındı. En sık görülen semptom baş ağrısıydı (%69,8). Kırk beş yaş altı hastalarda lohusalık ve malignite en sık görülen risk faktörleri iken, 45 yaş üstü hastalarda anemi ve malignite en sık görülen risk faktörleri idi. SVT’nin en sık yerleşim yeri transvers sinüs (%69,8) olarak bulundu. Taburculuk mRS skoru 47 hastada (%88,6) 0, 4 hastada (%7,5) 1 ve 2 hastada 4 idi. Altıncı ay takibinde hastaların 48’inde (%90,5) normal nörolojik muayene ile mRS skoru 0 olarak bulundu. Sonuç: Tek bir üçüncü basamak sevk merkezi deneyimini temsil eden çalışmamız, SVT’nin çoğunlukla üreme çağındaki kadınları etkilediğini göstermiştir. Çalışmamızdaki hastaların %90’ından fazlasının 6. ay takibinde mRS skoru 0 idi. Çalışmamızın sonuçları, son yıllarda gelişmiş nörogörüntüleme teknikleri ile SVT’nin erken teşhisinin sonuçları iyileştirdiğini ve özürlülüğü azalttığını göstermektedir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Mutlucan H, Batur Caglayan H, Nazliel B, TOKGOZ N, UCAR M (2022). Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. , 355 - 360. 10.4274/meandros.galenos.2022.26986
Chicago Mutlucan Havva meltem,Batur Caglayan Hale,Nazliel Bijen,TOKGOZ NIL,UCAR MURAT Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. (2022): 355 - 360. 10.4274/meandros.galenos.2022.26986
MLA Mutlucan Havva meltem,Batur Caglayan Hale,Nazliel Bijen,TOKGOZ NIL,UCAR MURAT Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. , 2022, ss.355 - 360. 10.4274/meandros.galenos.2022.26986
AMA Mutlucan H,Batur Caglayan H,Nazliel B,TOKGOZ N,UCAR M Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. . 2022; 355 - 360. 10.4274/meandros.galenos.2022.26986
Vancouver Mutlucan H,Batur Caglayan H,Nazliel B,TOKGOZ N,UCAR M Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. . 2022; 355 - 360. 10.4274/meandros.galenos.2022.26986
IEEE Mutlucan H,Batur Caglayan H,Nazliel B,TOKGOZ N,UCAR M "Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience." , ss.355 - 360, 2022. 10.4274/meandros.galenos.2022.26986
ISNAD Mutlucan, Havva meltem vd. "Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience". (2022), 355-360. https://doi.org/10.4274/meandros.galenos.2022.26986
APA Mutlucan H, Batur Caglayan H, Nazliel B, TOKGOZ N, UCAR M (2022). Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. Meandros Medical And Dental Journal, 23(3), 355 - 360. 10.4274/meandros.galenos.2022.26986
Chicago Mutlucan Havva meltem,Batur Caglayan Hale,Nazliel Bijen,TOKGOZ NIL,UCAR MURAT Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. Meandros Medical And Dental Journal 23, no.3 (2022): 355 - 360. 10.4274/meandros.galenos.2022.26986
MLA Mutlucan Havva meltem,Batur Caglayan Hale,Nazliel Bijen,TOKGOZ NIL,UCAR MURAT Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. Meandros Medical And Dental Journal, vol.23, no.3, 2022, ss.355 - 360. 10.4274/meandros.galenos.2022.26986
AMA Mutlucan H,Batur Caglayan H,Nazliel B,TOKGOZ N,UCAR M Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. Meandros Medical And Dental Journal. 2022; 23(3): 355 - 360. 10.4274/meandros.galenos.2022.26986
Vancouver Mutlucan H,Batur Caglayan H,Nazliel B,TOKGOZ N,UCAR M Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience. Meandros Medical And Dental Journal. 2022; 23(3): 355 - 360. 10.4274/meandros.galenos.2022.26986
IEEE Mutlucan H,Batur Caglayan H,Nazliel B,TOKGOZ N,UCAR M "Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience." Meandros Medical And Dental Journal, 23, ss.355 - 360, 2022. 10.4274/meandros.galenos.2022.26986
ISNAD Mutlucan, Havva meltem vd. "Evaluation of Risk Factors, Clinical Characteristics, and Prognosis in Cerebral Venous Thrombosis: A Single Tertiary Center Experience". Meandros Medical And Dental Journal 23/3 (2022), 355-360. https://doi.org/10.4274/meandros.galenos.2022.26986