The aim of this study was to determine infant deaths and causes of deaths in Sivas. In this descriptive study, infant deaths between 2013-2020 were analysed using Sivas Provincial Health Directorate data. Infant mortality rate, neonatal mortality rate, early neonatal, late neonatal and post neonatal mortality rates were calculated and their relationship with some maternal and infant characteristics were evaluated. Percentage distribution and Chi-square test were used for evaluation. The level of error p<0.05 was taken. In our study, it was determined that infant deaths in Sivas decreased between 2013-2020 and was 7.06 per thousand in 2020. Among the neonatal deaths, early neonatal deaths were the most common (54% in 2020) and it was found to have an increasing trend in recent years. In male babies (54.4%), babies of mothers under 35 years old (81.1%), 2nd and 3rd pregnancies (42.3%), 37 weeks and below 2500 g births (62.4%, respectively; 61.3%) infant deaths were higher. Congenital anomalies (10.6%), lung failure (9.5%), respiratory distress syndrome (7.9%), sepsis (7.4%) and prematurity (6.5%) were determined as the main causes of infant deaths. To detect congenital anomalies in the early period, to reduce prematurity, sepsis, and respiratory problems, it can be recommended to perform pregnancy and postnatal follow-up very well and not to delay the follow-up of the risky pregnant women.