TY  - JOUR
TI  - The association of new atherosclerosis markers with coronary collaterals in  chronic total occlusion patients
AB  - Objectives: In the present study, we investigated the relationship between mentioned markers and chronic total occlusion collateral  development. Patients and methods: A total of 243 patients (210 males, 33 females; mean age: 63.3±11.5; range, 51 to 76 years) who underwent  coronary angiography due to typical chest pain or myocardial ischemia detected in noninvasive stress tests and diagnosed with  ≥1 major coronary artery occlusion between January and September 2020 were included in the cross-sectional observational study.  The angiographic collateral index was determined according to the Cohen-Rentrop classification. The patients were divided into two  groups according to the sufficiency of collateral development: the well-developed collaterals group (n=155) and the poor-developed  collaterals group (n=88). Results: Statistically significant parameters in univariate logistic regression analysis were evaluated with multivariate (stepwise)  logistic regression analysis; as a result, presence of chronic total occlusion in left anterior descending artery (odds ratio [OR]=2.447;  95% confidence interval [CI], 1.160-5.162; p=0.019), total number of occlusions (OR=3.503; 95% CI, 1.445-8.494; p=0.006), left  ventricular ejection fraction (OR=1.056; 95% CI, 1.022-1.091; p=0.001), and the atherogenic index of plasma (OR=0.017; 95% CI,  1.022-1.091; p<0.001) were independently associated with well-developed collaterals. Although the triglyceride-glucose index  had statistical significance in the univariate analysis, it was not detected as an independent variable in the multivariate analysis.  The monocyte-lymphocyte ratio was not significant in the univariate analysis. Conclusion: Of the new atherosclerosis markers, only the atherogenic index of plasma had an independent association with poor collateral  development.
AU  - Öğütveren, Muhammed Mürsel
AU  - emlek, nadir
AU  - AYDIN, Cihan
AU  - Özyıldız, Ali Gökhan
AU  - Ergül, Elif
AU  - ÖZTÜRK, Muhammet
DO  - 10.5606/e-cvsi.2022.1368
PY  - 2022
JO  - Cardiovascular surgery and interventions
VL  - 9
IS  - 3
SN  - 2148-9211
SP  - 152
EP  - 158
DB  - TRDizin
UR  - http://search/yayin/detay/1135808
ER  -