Role of Endothelial Cells in Hematological Malignancies

da Costa Cacemiro, Maira; Barretto, Gabriel Dessotti; Pereira, Illy; Castro, Fab ola Atti de; Cominal, Juçara Gastaldi

doi:10.14744/ejmo.2022.67393

Role of Endothelial Cells in Hematological Malignancies

Illy Pereira, (Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil)

Maira da Costa Cacemiro, (Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil)

Juçara Gastaldi Cominal, (Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil)

Gabriel Dessotti Barretto, (Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil)

Fab ola Atti de Castro (Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil)

Eurasian Journal of Medicine and Oncology

3 0

Yıl: 2022 Cilt: 6 Sayı: 3 Sayfa Aralığı: 210 - 218 Metin Dili: İngilizce DOI: 10.14744/ejmo.2022.67393 İndeks Tarihi: 03-11-2022

Role of Endothelial Cells in Hematological Malignancies

Öz:

Endothelial cells (EC) are key elements of vascularized tissues that form a single-cell layer that connects the vessels to the surrounding tissues. EC participate in the regulation of blood hemostasis, leukocyte homing, acute inflammation, wound healing, and antigen presentation. EC subpopulations are characterized by diverse structures, functions, and molecular profiles. In bone marrow, EC are part of the hematopoietic stem cell vascular and endosteal niche, where they play well-defined roles in hematopoietic stem cell functioning and maintenance, and reside surrounding sinu- soids and blood vessels. In the past years, the clinical and pathophysiological roles of EC have been explored due to their contribution to neoangiogenesis and alterations in the vascular endothelium functions in hematological diseases. The present review discusses the EC contribution to pathogenesis of hematological malignancies and their potential use as therapeutic target in these diseases.

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APA	Pereira I, da Costa Cacemiro M, Cominal J, Barretto G, Castro F (2022). Role of Endothelial Cells in Hematological Malignancies. , 210 - 218. 10.14744/ejmo.2022.67393
Chicago	Pereira Illy,da Costa Cacemiro Maira,Cominal Juçara Gastaldi,Barretto Gabriel Dessotti,Castro Fab ola Atti de Role of Endothelial Cells in Hematological Malignancies. (2022): 210 - 218. 10.14744/ejmo.2022.67393
MLA	Pereira Illy,da Costa Cacemiro Maira,Cominal Juçara Gastaldi,Barretto Gabriel Dessotti,Castro Fab ola Atti de Role of Endothelial Cells in Hematological Malignancies. , 2022, ss.210 - 218. 10.14744/ejmo.2022.67393
AMA	Pereira I,da Costa Cacemiro M,Cominal J,Barretto G,Castro F Role of Endothelial Cells in Hematological Malignancies. . 2022; 210 - 218. 10.14744/ejmo.2022.67393
Vancouver	Pereira I,da Costa Cacemiro M,Cominal J,Barretto G,Castro F Role of Endothelial Cells in Hematological Malignancies. . 2022; 210 - 218. 10.14744/ejmo.2022.67393
IEEE	Pereira I,da Costa Cacemiro M,Cominal J,Barretto G,Castro F "Role of Endothelial Cells in Hematological Malignancies." , ss.210 - 218, 2022. 10.14744/ejmo.2022.67393
ISNAD	Pereira, Illy vd. "Role of Endothelial Cells in Hematological Malignancies". (2022), 210-218. https://doi.org/10.14744/ejmo.2022.67393

APA	Pereira I, da Costa Cacemiro M, Cominal J, Barretto G, Castro F (2022). Role of Endothelial Cells in Hematological Malignancies. Eurasian Journal of Medicine and Oncology, 6(3), 210 - 218. 10.14744/ejmo.2022.67393
Chicago	Pereira Illy,da Costa Cacemiro Maira,Cominal Juçara Gastaldi,Barretto Gabriel Dessotti,Castro Fab ola Atti de Role of Endothelial Cells in Hematological Malignancies. Eurasian Journal of Medicine and Oncology 6, no.3 (2022): 210 - 218. 10.14744/ejmo.2022.67393
MLA	Pereira Illy,da Costa Cacemiro Maira,Cominal Juçara Gastaldi,Barretto Gabriel Dessotti,Castro Fab ola Atti de Role of Endothelial Cells in Hematological Malignancies. Eurasian Journal of Medicine and Oncology, vol.6, no.3, 2022, ss.210 - 218. 10.14744/ejmo.2022.67393
AMA	Pereira I,da Costa Cacemiro M,Cominal J,Barretto G,Castro F Role of Endothelial Cells in Hematological Malignancies. Eurasian Journal of Medicine and Oncology. 2022; 6(3): 210 - 218. 10.14744/ejmo.2022.67393
Vancouver	Pereira I,da Costa Cacemiro M,Cominal J,Barretto G,Castro F Role of Endothelial Cells in Hematological Malignancies. Eurasian Journal of Medicine and Oncology. 2022; 6(3): 210 - 218. 10.14744/ejmo.2022.67393
IEEE	Pereira I,da Costa Cacemiro M,Cominal J,Barretto G,Castro F "Role of Endothelial Cells in Hematological Malignancies." Eurasian Journal of Medicine and Oncology, 6, ss.210 - 218, 2022. 10.14744/ejmo.2022.67393
ISNAD	Pereira, Illy vd. "Role of Endothelial Cells in Hematological Malignancies". Eurasian Journal of Medicine and Oncology 6/3 (2022), 210-218. https://doi.org/10.14744/ejmo.2022.67393