Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole

Gurgan, Muazzez; OZTURK, Ibrahim Ismet

doi:10.17350/HJSE19030000275

Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole

İbrahim İsmet ÖZTÜRK, (Tekirdağ Namık Kemal Üniversitesi, Kimya Bölümü, Tekirdağ, Türkiye)

Muazzez GÜRGAN (Tekirdağ Namık Kemal Üniversitesi, Biyoloji Bölümü, Tekirdağ, Türkiye)

Hittite Journal of Science and Engineering

5 3

Yıl: 2022 Cilt: 9 Sayı: 3 Sayfa Aralığı: 225 - 233 Metin Dili: İngilizce DOI: 10.17350/HJSE19030000275 İndeks Tarihi: 06-11-2022

Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole

Öz:

Bismuth, known as a heavy metal, is excluded from this class due to its low toxicity. Due to this feature, bismuth containing compounds have always been interesting compounds in the field of medicinal chemistry. For this reason, the discovery of new bismuth compounds and the investigation of their biological properties are very important for this field. In this study, three new bismuth(III) compounds formulated as [Bi(L)2X3] (L: 5-chloro-2-mercaptobenzothiazole (ClMBZT); X: Cl, Br, and I) were synthesized for the first time and, the molecular structure of them were elucidated by a series of spectroscopic techniques. Thermal stability and degradation steps of the title compounds were analyzed by Thermogravimetric-Differential Thermal Analysis (TG-DTA). The antibacterial study has been conducted against six strains bacteria, and the results indicated that bismuth(III) compounds generally showed more effective antibacterial activity than free ligand. The anti-inflammatory potential of bismuth(III) compounds was investigated through in vitro lipoxygenase enzyme inhibition studies. The results show that bismuth(III) compounds have higher anti-inflammatory potential than free ligand.

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APA	OZTURK I, Gurgan M (2022). Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. , 225 - 233. 10.17350/HJSE19030000275
Chicago	OZTURK Ibrahim Ismet,Gurgan Muazzez Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. (2022): 225 - 233. 10.17350/HJSE19030000275
MLA	OZTURK Ibrahim Ismet,Gurgan Muazzez Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. , 2022, ss.225 - 233. 10.17350/HJSE19030000275
AMA	OZTURK I,Gurgan M Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. . 2022; 225 - 233. 10.17350/HJSE19030000275
Vancouver	OZTURK I,Gurgan M Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. . 2022; 225 - 233. 10.17350/HJSE19030000275
IEEE	OZTURK I,Gurgan M "Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole." , ss.225 - 233, 2022. 10.17350/HJSE19030000275
ISNAD	OZTURK, Ibrahim Ismet - Gurgan, Muazzez. "Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole". (2022), 225-233. https://doi.org/10.17350/HJSE19030000275

APA	OZTURK I, Gurgan M (2022). Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. Hittite Journal of Science and Engineering, 9(3), 225 - 233. 10.17350/HJSE19030000275
Chicago	OZTURK Ibrahim Ismet,Gurgan Muazzez Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. Hittite Journal of Science and Engineering 9, no.3 (2022): 225 - 233. 10.17350/HJSE19030000275
MLA	OZTURK Ibrahim Ismet,Gurgan Muazzez Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. Hittite Journal of Science and Engineering, vol.9, no.3, 2022, ss.225 - 233. 10.17350/HJSE19030000275
AMA	OZTURK I,Gurgan M Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. Hittite Journal of Science and Engineering. 2022; 9(3): 225 - 233. 10.17350/HJSE19030000275
Vancouver	OZTURK I,Gurgan M Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole. Hittite Journal of Science and Engineering. 2022; 9(3): 225 - 233. 10.17350/HJSE19030000275
IEEE	OZTURK I,Gurgan M "Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole." Hittite Journal of Science and Engineering, 9, ss.225 - 233, 2022. 10.17350/HJSE19030000275
ISNAD	OZTURK, Ibrahim Ismet - Gurgan, Muazzez. "Synthesis, Characterization, Anti-bacterial and Antiinflammatory Activities of Bismuth(III) Complexes Based on 5-chloro-2-mercaptobenzothiazole". Hittite Journal of Science and Engineering 9/3 (2022), 225-233. https://doi.org/10.17350/HJSE19030000275