Assessment of auditory functions in patients with hepatic glycogen storage diseases

kılıç, ayşe; Tutar, Hakan; INCI, ASLI; özsaydı aktaşoğlu, ekin; Ezgu, Fatih Suheyl; emecen şanlı, merve; YILDIRIM GÖKAY, NURİYE; Gunduz, Bulent; OKUR, ILYAS; Tumer, Leyla

doi:10.24953/turkjped.2022.142

Assessment of auditory functions in patients with hepatic glycogen storage diseases

Merve EMECEN ŞANLI, (Gazi Üniversitesi, Tıp Fakültesi, Doğuştan Çocuklarda Metabolizma Hastalıkları Anabilim Dalı, Ankara, Türkiye)

Nuriye YILDIRIM GÖKAY, (Gazi Üniversitesi, Sağlık Bilimleri Fakültesi, Odyoloji Anabilim Dalı, Ankara, Türkiye)

Hakan TUTAR, (Gazi Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, Ankara, Türkiye)

Bulent Gunduz, (Gazi Üniversitesi, Sağlık Bilimleri Fakültesi, Odyoloji Anabilim Dalı, Ankara, Türkiye)

ekin özsaydı aktaşoğlu, (Gazi Üniversitesi, Tıp Fakültesi, Doğuştan Çocuklarda Metabolizma Hastalıkları Anabilim Dalı, Ankara, Türkiye)

Ayşe KILIÇ, (Gazi Üniversitesi, Tıp Fakültesi, Doğuştan Çocuklarda Metabolizma Hastalıkları Anabilim Dalı, Ankara, Türkiye)

ASLI INCI, (Gazi Üniversitesi, Tıp Fakültesi, Doğuştan Çocuklarda Metabolizma Hastalıkları Anabilim Dalı, Ankara, Türkiye)

İlyas OKUR, (Gazi Üniversitesi, Tıp Fakültesi, Doğuştan Çocuklarda Metabolizma Hastalıkları Anabilim Dalı, Ankara, Türkiye)

Fatih Süheyl EZGÜ, (Gazi Üniversitesi, Tıp Fakültesi, Doğuştan Çocuklarda Metabolizma Hastalıkları Anabilim Dalı, Ankara, Türkiye)

Leyla TÜMER (Gazi Üniversitesi, Tıp Fakültesi, Doğuştan Çocuklarda Metabolizma Hastalıkları Anabilim Dalı, Ankara, Türkiye)

Turkish Journal of Pediatrics

5 0

Yıl: 2022 Cilt: 64 Sayı: 4 Sayfa Aralığı: 658 - 670 Metin Dili: İngilizce DOI: 10.24953/turkjped.2022.142 İndeks Tarihi: 15-12-2022

Assessment of auditory functions in patients with hepatic glycogen storage diseases

Öz:

Background. Hepatic glycogen storage diseases are a group of diseases manifesting mainly with hypoglycemia and hepatomegaly. The patients require frequent daytime and nocturnal feedings. Hypoglycemia may cause sensorineural hearing loss and nocturnal feeding is a risk factor for the development of gastroesophageal reflux that may cause chronic otitis media and hearing loss consequently. We aimed to determine the prevalence and characteristics of hearing loss in hepatic glycogen storage diseases. Methods. A total of 24 patients with hepatic glycogen storage disease (15 glycogen storage disease type I and 9 non type I) and 24 age/sex matched healthy controls were enrolled in the study. Pure tone audiometer, immitansmetry, acoustic reflex measurement, otoacoustic emission test (OAE) and auditory brainstem response (ABR) tests were applied to all participants. Results. Hearing loss was determined in 17/24 patients (12 glycogen storage disease type I and 5 non type I) with pure tone audiometer. Interpretation of all the findings revealed a total of 8 patients had conductive and 9 had mixed hearing loss. All parameters were significantly different than the control group. Conclusions. This is the first study to comprehensively assess the auditory functions of patients with hepatic glycogen storage disease. Audiological findings determined a significantly increased prevalence of conductive/ mixed type hearing loss in the patient group which is a new finding in the literature. Further studies with extended patient numbers are required to enlighten the underlying pathophysiology.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	emecen şanlı m, YILDIRIM GÖKAY N, Tutar H, Gunduz B, özsaydı aktaşoğlu e, kılıç a, INCI A, OKUR I, Ezgu F, Tumer L (2022). Assessment of auditory functions in patients with hepatic glycogen storage diseases. , 658 - 670. 10.24953/turkjped.2022.142
Chicago	emecen şanlı merve,YILDIRIM GÖKAY NURİYE,Tutar Hakan,Gunduz Bulent,özsaydı aktaşoğlu ekin,kılıç ayşe,INCI ASLI,OKUR ILYAS,Ezgu Fatih Suheyl,Tumer Leyla Assessment of auditory functions in patients with hepatic glycogen storage diseases. (2022): 658 - 670. 10.24953/turkjped.2022.142
MLA	emecen şanlı merve,YILDIRIM GÖKAY NURİYE,Tutar Hakan,Gunduz Bulent,özsaydı aktaşoğlu ekin,kılıç ayşe,INCI ASLI,OKUR ILYAS,Ezgu Fatih Suheyl,Tumer Leyla Assessment of auditory functions in patients with hepatic glycogen storage diseases. , 2022, ss.658 - 670. 10.24953/turkjped.2022.142
AMA	emecen şanlı m,YILDIRIM GÖKAY N,Tutar H,Gunduz B,özsaydı aktaşoğlu e,kılıç a,INCI A,OKUR I,Ezgu F,Tumer L Assessment of auditory functions in patients with hepatic glycogen storage diseases. . 2022; 658 - 670. 10.24953/turkjped.2022.142
Vancouver	emecen şanlı m,YILDIRIM GÖKAY N,Tutar H,Gunduz B,özsaydı aktaşoğlu e,kılıç a,INCI A,OKUR I,Ezgu F,Tumer L Assessment of auditory functions in patients with hepatic glycogen storage diseases. . 2022; 658 - 670. 10.24953/turkjped.2022.142
IEEE	emecen şanlı m,YILDIRIM GÖKAY N,Tutar H,Gunduz B,özsaydı aktaşoğlu e,kılıç a,INCI A,OKUR I,Ezgu F,Tumer L "Assessment of auditory functions in patients with hepatic glycogen storage diseases." , ss.658 - 670, 2022. 10.24953/turkjped.2022.142
ISNAD	emecen şanlı, merve vd. "Assessment of auditory functions in patients with hepatic glycogen storage diseases". (2022), 658-670. https://doi.org/10.24953/turkjped.2022.142

APA	emecen şanlı m, YILDIRIM GÖKAY N, Tutar H, Gunduz B, özsaydı aktaşoğlu e, kılıç a, INCI A, OKUR I, Ezgu F, Tumer L (2022). Assessment of auditory functions in patients with hepatic glycogen storage diseases. Turkish Journal of Pediatrics, 64(4), 658 - 670. 10.24953/turkjped.2022.142
Chicago	emecen şanlı merve,YILDIRIM GÖKAY NURİYE,Tutar Hakan,Gunduz Bulent,özsaydı aktaşoğlu ekin,kılıç ayşe,INCI ASLI,OKUR ILYAS,Ezgu Fatih Suheyl,Tumer Leyla Assessment of auditory functions in patients with hepatic glycogen storage diseases. Turkish Journal of Pediatrics 64, no.4 (2022): 658 - 670. 10.24953/turkjped.2022.142
MLA	emecen şanlı merve,YILDIRIM GÖKAY NURİYE,Tutar Hakan,Gunduz Bulent,özsaydı aktaşoğlu ekin,kılıç ayşe,INCI ASLI,OKUR ILYAS,Ezgu Fatih Suheyl,Tumer Leyla Assessment of auditory functions in patients with hepatic glycogen storage diseases. Turkish Journal of Pediatrics, vol.64, no.4, 2022, ss.658 - 670. 10.24953/turkjped.2022.142
AMA	emecen şanlı m,YILDIRIM GÖKAY N,Tutar H,Gunduz B,özsaydı aktaşoğlu e,kılıç a,INCI A,OKUR I,Ezgu F,Tumer L Assessment of auditory functions in patients with hepatic glycogen storage diseases. Turkish Journal of Pediatrics. 2022; 64(4): 658 - 670. 10.24953/turkjped.2022.142
Vancouver	emecen şanlı m,YILDIRIM GÖKAY N,Tutar H,Gunduz B,özsaydı aktaşoğlu e,kılıç a,INCI A,OKUR I,Ezgu F,Tumer L Assessment of auditory functions in patients with hepatic glycogen storage diseases. Turkish Journal of Pediatrics. 2022; 64(4): 658 - 670. 10.24953/turkjped.2022.142
IEEE	emecen şanlı m,YILDIRIM GÖKAY N,Tutar H,Gunduz B,özsaydı aktaşoğlu e,kılıç a,INCI A,OKUR I,Ezgu F,Tumer L "Assessment of auditory functions in patients with hepatic glycogen storage diseases." Turkish Journal of Pediatrics, 64, ss.658 - 670, 2022. 10.24953/turkjped.2022.142
ISNAD	emecen şanlı, merve vd. "Assessment of auditory functions in patients with hepatic glycogen storage diseases". Turkish Journal of Pediatrics 64/4 (2022), 658-670. https://doi.org/10.24953/turkjped.2022.142