Cyclopentolate eye drops-induced anaphylaxis in an infant
Yıl: 2022 Cilt: 64 Sayı: 5 Sayfa Aralığı: 915 - 918 Metin Dili: İngilizce DOI: 10.24953/turkjped.2022.125 İndeks Tarihi: 15-12-2022
Cyclopentolate eye drops-induced anaphylaxis in an infant
Öz: Background. Cyclopentolate is frequently used as a mydriatic agent during ophthalmological examinations in childhood and hypersensitivity reactions associated with this drug are rare. We aim to report an infant who experienced anaphylaxis due to cyclopentolate eye drops. Case. A nine-month-old girl, who was being followed up with a diagnosis of retinoblastoma, presented for consultation for urticaria, cough, stridor, and dyspnea that developed after the administration of topical cyclopentolate to the eyes. The patient was diagnosed with anaphylaxis and treated with adrenaline. During the follow-up, tropicamide was used safely as an alternative drug. Conclusions. In children, hypersensitivity reactions due to cyclopentolate are very rare. Only four pediatric patients were reported in the literature to have developed an allergic reaction after the administration of cyclopentolate eye drops. We present here the youngest patient who developed anaphylaxis with cyclopentolate eye drops. Anaphylaxis due to cyclopentolate should be kept in mind, rapidly recognized, and treated when a reaction develops.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
- 1. Villarreal O. Reliability of diagnostic tests for contact allergy to mydriatic eyedrops. Contact Dermatitis 1998; 38: 150-154. https://doi. org/10.1111/j.1600-0536.1998.tb05682.x
- 2. Jones LW, Hodes DT. Possible allergic reactions to cyclopentolate hydrochloride: case reports with literature review of uses and adverse reactions. Ophthalmic Physiol Opt 1991; 11: 16-21. https://doi. org/10.1111/j.1475-1313.1991.tb00189.x
- 3. Tayman C, Mete E, Catal F, Akca H. Anaphylactic reaction due to cyclopentolate in a 4-year-old child. J Investig Allergol Clin Immunol 2010; 20: 347-348.
- 4. Diesner SC, Bannert C, Gruber S, Dehlink E, Eiwegger T, Szepfalusi Z. The mydriaticum cyclopentolate induces severe allergy in a 5-yearold child. Klin Padiatr 2014; 226: 252-253. https://doi. org/10.1055/s-0034-1375700
- 5. Rengstorff RH, Doughty CB. Mydriatic and cycloplegic drugs: a review of ocular and systemic complications. Am J Optom Physiol Opt 1982; 59: 162-177. https://doi.org/10.1097/00006324- 198202000-00008
- 6. Kaila T, Huupponen R, Salminen L, Iisalo E. Systemic absorption of ophthalmic cyclopentolate. Am J Ophthalmol 1989; 107: 562-564. https://doi. org/10.1016/0002-9394(89)90515-1
- 7. Loewen N, Barry JC. The use of cycloplegic agents. Results of a 1999 survey of Germanspeaking centers for pediatric ophthalmology and strabology. Strabismus 2000; 8: 91-99. https://doi. org/10.1076/0927-3972(200006)821-2FT091
- 8. van Minderhout HM, Joosse MV, Grootendorst DC, Schalij-Delfos NE. Adverse reactions following routine anticholinergic eye drops in a paediatric population: an observational cohort study. BMJ Open 2015; 5: e008798. https://doi.org/10.1136/ bmjopen-2015-008798
- 9. Brown SGA. Clinical features and severity grading of anaphylaxis. J Allergy Clin Immunol 2004; 114: 371-376. https://doi.org/10.1016/j.jaci.2004.04.029
- 10. Newman DK, Jordan K. Generalised urticaria induced by topical cyclopentolate. Eye (Lond) 1996; 10 (Pt 6): 750-751. https://doi.org/10.1038/ eye.1996.176
- 11. Muñoz-Bellido FJ, Beltrán A, Bellido J. Contact urticaria due to cyclopentolate hydrochloride. Allergy 2000; 55: 198-199. https://doi.org/10.1034/ j.1398-9995.2000.00447.x
- 12. Robenshtok E, Luria S, Tashma Z, Hourvitz A. Adverse reaction to atropine and the treatment of organophosphate intoxication. Isr Med Assoc J 2002; 4: 535-539.
- 13. Weiler CR, Austen KF, Akin C, et al. AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management. J Allergy Clin Immunol 2019; 144: 883-896. https://doi.org/10.1016/j.jaci.2019.08.023
- 14. McHugh K, Repanshek Z. Anaphylaxis: emergency department treatment. Emerg Med Clin North Am 2022; 40: 19-32. https://doi.org/10.1016/j. emc.2021.08.004
| APA | Polat Terece S, Ertoy Karagol H, Koken G, Atalay H, Topuz Türkcan B, vural ö, BAKIRTAS A (2022). Cyclopentolate eye drops-induced anaphylaxis in an infant. , 915 - 918. 10.24953/turkjped.2022.125 |
| Chicago | Polat Terece Sinem,Ertoy Karagol Hacer Ilbilge,Koken Gizem,Atalay Hatice Tuba,Topuz Türkcan Büşra,vural özge,BAKIRTAS ARZU Cyclopentolate eye drops-induced anaphylaxis in an infant. (2022): 915 - 918. 10.24953/turkjped.2022.125 |
| MLA | Polat Terece Sinem,Ertoy Karagol Hacer Ilbilge,Koken Gizem,Atalay Hatice Tuba,Topuz Türkcan Büşra,vural özge,BAKIRTAS ARZU Cyclopentolate eye drops-induced anaphylaxis in an infant. , 2022, ss.915 - 918. 10.24953/turkjped.2022.125 |
| AMA | Polat Terece S,Ertoy Karagol H,Koken G,Atalay H,Topuz Türkcan B,vural ö,BAKIRTAS A Cyclopentolate eye drops-induced anaphylaxis in an infant. . 2022; 915 - 918. 10.24953/turkjped.2022.125 |
| Vancouver | Polat Terece S,Ertoy Karagol H,Koken G,Atalay H,Topuz Türkcan B,vural ö,BAKIRTAS A Cyclopentolate eye drops-induced anaphylaxis in an infant. . 2022; 915 - 918. 10.24953/turkjped.2022.125 |
| IEEE | Polat Terece S,Ertoy Karagol H,Koken G,Atalay H,Topuz Türkcan B,vural ö,BAKIRTAS A "Cyclopentolate eye drops-induced anaphylaxis in an infant." , ss.915 - 918, 2022. 10.24953/turkjped.2022.125 |
| ISNAD | Polat Terece, Sinem vd. "Cyclopentolate eye drops-induced anaphylaxis in an infant". (2022), 915-918. https://doi.org/10.24953/turkjped.2022.125 |
| APA | Polat Terece S, Ertoy Karagol H, Koken G, Atalay H, Topuz Türkcan B, vural ö, BAKIRTAS A (2022). Cyclopentolate eye drops-induced anaphylaxis in an infant. Turkish Journal of Pediatrics, 64(5), 915 - 918. 10.24953/turkjped.2022.125 |
| Chicago | Polat Terece Sinem,Ertoy Karagol Hacer Ilbilge,Koken Gizem,Atalay Hatice Tuba,Topuz Türkcan Büşra,vural özge,BAKIRTAS ARZU Cyclopentolate eye drops-induced anaphylaxis in an infant. Turkish Journal of Pediatrics 64, no.5 (2022): 915 - 918. 10.24953/turkjped.2022.125 |
| MLA | Polat Terece Sinem,Ertoy Karagol Hacer Ilbilge,Koken Gizem,Atalay Hatice Tuba,Topuz Türkcan Büşra,vural özge,BAKIRTAS ARZU Cyclopentolate eye drops-induced anaphylaxis in an infant. Turkish Journal of Pediatrics, vol.64, no.5, 2022, ss.915 - 918. 10.24953/turkjped.2022.125 |
| AMA | Polat Terece S,Ertoy Karagol H,Koken G,Atalay H,Topuz Türkcan B,vural ö,BAKIRTAS A Cyclopentolate eye drops-induced anaphylaxis in an infant. Turkish Journal of Pediatrics. 2022; 64(5): 915 - 918. 10.24953/turkjped.2022.125 |
| Vancouver | Polat Terece S,Ertoy Karagol H,Koken G,Atalay H,Topuz Türkcan B,vural ö,BAKIRTAS A Cyclopentolate eye drops-induced anaphylaxis in an infant. Turkish Journal of Pediatrics. 2022; 64(5): 915 - 918. 10.24953/turkjped.2022.125 |
| IEEE | Polat Terece S,Ertoy Karagol H,Koken G,Atalay H,Topuz Türkcan B,vural ö,BAKIRTAS A "Cyclopentolate eye drops-induced anaphylaxis in an infant." Turkish Journal of Pediatrics, 64, ss.915 - 918, 2022. 10.24953/turkjped.2022.125 |
| ISNAD | Polat Terece, Sinem vd. "Cyclopentolate eye drops-induced anaphylaxis in an infant". Turkish Journal of Pediatrics 64/5 (2022), 915-918. https://doi.org/10.24953/turkjped.2022.125 |
