Yıl: 2021 Cilt: 21 Sayı: 1 Sayfa Aralığı: 1 - 7 Metin Dili: İngilizce DOI: 10.31467/uluaricilik.877301 İndeks Tarihi: 20-11-2022

Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES

Öz:
Propolis is a natural product, and it is of a great interest due to the possible uses of non-synthetic supplements in improving metabolic disorders. To support this claim, the current study was designed and presented. In this study, six propolis extracts obtained from different location of Turkey were investigated to prove the beneficial therapeutic properties such as inhibition potent against some enzymes and levels of antioxidant. IC50 results of α-glucosidase (0.208-0.426 mg/mL) and α-amylase (0.487-0.938 mg/mL) were found the variable range. Moreover, antioxidant results of them were given to support the inhibition degrees. According to the total phenolic (TPC) and antioxidant data, S4 was noted as the most efficient sample. Future studies are needed to investigate the biological effects of propolis, but the ultimate evaluating showed that it could be a significant source thanks to its nutritional and clinical potential.
Anahtar Kelime:

Metabolik bozuklukların iyileştirilmesinde sentetik olmayan takviyelerin olası kullanımı nedeniyle, doğal bir ürün olan propolis büyük ilgi görmektedir. Bu iddiayı desteklemek için mevcut çalışma planlandı ve ortaya kondu. Bu çalışmada, Türkiye'nin farklı bölgelerinden elde edilen altı propolis ekstratının tedavi amacıyla kullanılabilmesi adına faydalı özelliklerini ortaya koymak için bazı enzimlere karşı inhibisyon etkileri ve antioksidan seviyeleri araştırıldı. α-glukozidaz IC50 sonuçları 0,208-0,426 mg/mL ve α-amilaz IC50 sonuçları 0,487-0,938 mg / mL aralığında bulundu. Ayrıca, inhibisyon etki derecelerini desteklemek için antioksidan aktivite sonuçları da verildi. Toplam fenolik (TPC) ve antioksidan verilerine göre, S4 en verimli örnek olarak kaydedildi. Propolisin biyolojik etkilerini araştırmak için ileride yapılacak yeni çalışmalara ihtiyaç vardır, ancak sonuç olarak, propolisin beslenme ve klinik potansiyeli olarak dikkate değer bir kaynak olabileceğini göstermektedir.

Öz:
Metabolik bozuklukların iyileştirilmesinde sentetik olmayan takviyelerin olası kullanımı nedeniyle, doğal bir ürün olan propolis büyük ilgi görmektedir. Bu iddiayı desteklemek için mevcut çalışma planlandı ve ortaya kondu. Bu çalışmada, Türkiye'nin farklı bölgelerinden elde edilen altı propolis ekstratının tedavi amacıyla kullanılabilmesi adına faydalı özelliklerini ortaya koymak için bazı enzimlere karşı inhibisyon etkileri ve antioksidan seviyeleri araştırıldı. α-glukozidaz IC50 sonuçları 0,208-0,426 mg/mL ve α-amilaz IC50 sonuçları 0,487-0,938 mg / mL aralığında bulundu. Ayrıca, inhibisyon etki derecelerini desteklemek için antioksidan aktivite sonuçları da verildi. Toplam fenolik (TPC) ve antioksidan verilerine göre, S4 en verimli örnek olarak kaydedildi. Propolisin biyolojik etkilerini araştırmak için ileride yapılacak yeni çalışmalara ihtiyaç vardır, ancak sonuç olarak, propolisin beslenme ve klinik potansiyeli olarak dikkate değer bir kaynak olabileceğini göstermektedir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA BALTAŞ N (2021). Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. , 1 - 7. 10.31467/uluaricilik.877301
Chicago BALTAŞ Nimet Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. (2021): 1 - 7. 10.31467/uluaricilik.877301
MLA BALTAŞ Nimet Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. , 2021, ss.1 - 7. 10.31467/uluaricilik.877301
AMA BALTAŞ N Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. . 2021; 1 - 7. 10.31467/uluaricilik.877301
Vancouver BALTAŞ N Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. . 2021; 1 - 7. 10.31467/uluaricilik.877301
IEEE BALTAŞ N "Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES." , ss.1 - 7, 2021. 10.31467/uluaricilik.877301
ISNAD BALTAŞ, Nimet. "Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES". (2021), 1-7. https://doi.org/10.31467/uluaricilik.877301
APA BALTAŞ N (2021). Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. Uludağ Arıcılık Dergisi, 21(1), 1 - 7. 10.31467/uluaricilik.877301
Chicago BALTAŞ Nimet Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. Uludağ Arıcılık Dergisi 21, no.1 (2021): 1 - 7. 10.31467/uluaricilik.877301
MLA BALTAŞ Nimet Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. Uludağ Arıcılık Dergisi, vol.21, no.1, 2021, ss.1 - 7. 10.31467/uluaricilik.877301
AMA BALTAŞ N Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. Uludağ Arıcılık Dergisi. 2021; 21(1): 1 - 7. 10.31467/uluaricilik.877301
Vancouver BALTAŞ N Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES. Uludağ Arıcılık Dergisi. 2021; 21(1): 1 - 7. 10.31467/uluaricilik.877301
IEEE BALTAŞ N "Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES." Uludağ Arıcılık Dergisi, 21, ss.1 - 7, 2021. 10.31467/uluaricilik.877301
ISNAD BALTAŞ, Nimet. "Α-GLUCOSIDASE AND α-AMYLASE INHIBITION OF SOME ETHANOLIC PROPOLIS SAMPLES". Uludağ Arıcılık Dergisi 21/1 (2021), 1-7. https://doi.org/10.31467/uluaricilik.877301