Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil

Korkmaz, Büşra; SENER, SILA OZLEM; YAYLI, Nurettin; BOZDAL, Gözde; ERİK, İshak; Alpay Karaoğlu, Şengül; TERZİOĞLU, SALİH

doi:10.55730/1300-0527.3430

Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil

Ishak ERIK, (Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Trabzon, Türkiye)

Gözde KILIÇ, (Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Botanik Anabilim Dalı, Trabzon, Türkiye)

Sıla Özlem ŞENER, (Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Trabzon, Türkiye)

Büşra KORKMAZ, (Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Trabzon, Türkiye)

Şengül Alpay KARAOĞLU, (Recep Tayyip Erdoğan Üniversitesi, Fen Fakültesi, Biyoloji Bölümü, Rize, Türkiye)

Salih TERZİOĞLU, (Karadeniz Teknik Üniversitesi, Orman Fakültesi, Orman Botaniği Bölümü, Trabzon, Türkiye)

Nurettin YAYLI (Karadeniz Teknik Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Trabzon, Türkiye)

Turkish Journal of Chemistry

8 0

Yıl: 2022 Cilt: 46 Sayı: 4 Sayfa Aralığı: 1234 - 1244 Metin Dili: İngilizce DOI: 10.55730/1300-0527.3430 İndeks Tarihi: 06-12-2022

Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil

Öz:

The essential oil (EO) of Cota tinctoria var. tinctoria was analyzed using GC-FID / MS. A total of 51 compounds were determined from this taxon, accounting for 99.79% in hydrodistillation. Monoterpenes were the primary chemical class for the volatile organic compounds in the EO (36.1%, 13 compounds). Borneol (18.1%), camphor (14.9%), and β-pinene (11.3%) were the major components in the EO of C. tinctoria var. tinctoria. The antimicrobial activities of EO and n-hexane, acetonitrile, methanol, and water solvent extracts of the taxon were screened in vitro against ten microorganisms. The EO yielded the best activity (15 mm, 372.5 MIC, 59600 μg/μL) against Mycobacterium smegmatis. The acetonitrile extract was the most active against the Staphylococcus aureus and Bacillus cereus with 274 μg/mL MIC value. $IC_{50}$ values for the lipase enzyme inhibitory activity of EO and solvent extracts (n-hexane, acetonitrile, methanol, and water) were found to be 59.80 ± 4.3285 μg/mL 68.28 ± 3.1215 μg/mL, 52.60 ± 3.7526 μg/mL, 48.73 ± 2.8265 μg/mL, and 99.50 ± 5.5678 μg/mL, respectively.

Anahtar Kelime: Antimicrobial Cota tinctoria var. tinctoria GC-FID/MS lipase inhibition volatile compounds

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ERİK İ, BOZDAL G, SENER S, Korkmaz B, Alpay Karaoğlu Ş, TERZİOĞLU S, YAYLI N (2022). Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. , 1234 - 1244. 10.55730/1300-0527.3430
Chicago	ERİK İshak,BOZDAL Gözde,SENER SILA OZLEM,Korkmaz Büşra,Alpay Karaoğlu Şengül,TERZİOĞLU SALİH,YAYLI Nurettin Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. (2022): 1234 - 1244. 10.55730/1300-0527.3430
MLA	ERİK İshak,BOZDAL Gözde,SENER SILA OZLEM,Korkmaz Büşra,Alpay Karaoğlu Şengül,TERZİOĞLU SALİH,YAYLI Nurettin Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. , 2022, ss.1234 - 1244. 10.55730/1300-0527.3430
AMA	ERİK İ,BOZDAL G,SENER S,Korkmaz B,Alpay Karaoğlu Ş,TERZİOĞLU S,YAYLI N Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. . 2022; 1234 - 1244. 10.55730/1300-0527.3430
Vancouver	ERİK İ,BOZDAL G,SENER S,Korkmaz B,Alpay Karaoğlu Ş,TERZİOĞLU S,YAYLI N Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. . 2022; 1234 - 1244. 10.55730/1300-0527.3430
IEEE	ERİK İ,BOZDAL G,SENER S,Korkmaz B,Alpay Karaoğlu Ş,TERZİOĞLU S,YAYLI N "Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil." , ss.1234 - 1244, 2022. 10.55730/1300-0527.3430
ISNAD	ERİK, İshak vd. "Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil". (2022), 1234-1244. https://doi.org/10.55730/1300-0527.3430

APA	ERİK İ, BOZDAL G, SENER S, Korkmaz B, Alpay Karaoğlu Ş, TERZİOĞLU S, YAYLI N (2022). Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. Turkish Journal of Chemistry, 46(4), 1234 - 1244. 10.55730/1300-0527.3430
Chicago	ERİK İshak,BOZDAL Gözde,SENER SILA OZLEM,Korkmaz Büşra,Alpay Karaoğlu Şengül,TERZİOĞLU SALİH,YAYLI Nurettin Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. Turkish Journal of Chemistry 46, no.4 (2022): 1234 - 1244. 10.55730/1300-0527.3430
MLA	ERİK İshak,BOZDAL Gözde,SENER SILA OZLEM,Korkmaz Büşra,Alpay Karaoğlu Şengül,TERZİOĞLU SALİH,YAYLI Nurettin Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. Turkish Journal of Chemistry, vol.46, no.4, 2022, ss.1234 - 1244. 10.55730/1300-0527.3430
AMA	ERİK İ,BOZDAL G,SENER S,Korkmaz B,Alpay Karaoğlu Ş,TERZİOĞLU S,YAYLI N Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. Turkish Journal of Chemistry. 2022; 46(4): 1234 - 1244. 10.55730/1300-0527.3430
Vancouver	ERİK İ,BOZDAL G,SENER S,Korkmaz B,Alpay Karaoğlu Ş,TERZİOĞLU S,YAYLI N Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil. Turkish Journal of Chemistry. 2022; 46(4): 1234 - 1244. 10.55730/1300-0527.3430
IEEE	ERİK İ,BOZDAL G,SENER S,Korkmaz B,Alpay Karaoğlu Ş,TERZİOĞLU S,YAYLI N "Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil." Turkish Journal of Chemistry, 46, ss.1234 - 1244, 2022. 10.55730/1300-0527.3430
ISNAD	ERİK, İshak vd. "Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil". Turkish Journal of Chemistry 46/4 (2022), 1234-1244. https://doi.org/10.55730/1300-0527.3430