TY  - JOUR
TI  - Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil
AB  - The essential oil (EO) of Cota tinctoria var. tinctoria was analyzed using GC-FID / MS. A total of 51 compounds were determined from this taxon, accounting for 99.79% in hydrodistillation. Monoterpenes were the primary chemical class for the volatile organic compounds in the EO (36.1%, 13 compounds). Borneol (18.1%), camphor (14.9%), and β-pinene (11.3%) were the major components in the EO of C. tinctoria var. tinctoria. The antimicrobial activities of EO and n-hexane, acetonitrile, methanol, and water solvent extracts of the taxon were screened in vitro against ten microorganisms. The EO yielded the best activity (15 mm, 372.5 MIC, 59600 μg/μL) against Mycobacterium smegmatis. The acetonitrile extract was the most active against the Staphylococcus aureus and Bacillus cereus with 274 μg/mL MIC value. $IC_{50}$ values for the lipase enzyme inhibitory activity of EO and solvent extracts (n-hexane, acetonitrile, methanol, and water) were found to be 59.80 ± 4.3285 μg/mL 68.28 ± 3.1215 μg/mL, 52.60 ± 3.7526 μg/mL, 48.73 ± 2.8265 μg/mL, and 99.50 ± 5.5678 μg/mL, respectively.
AU  - Korkmaz, Büşra
AU  - SENER, SILA OZLEM
AU  - YAYLI, Nurettin
AU  - BOZDAL, Gözde
AU  - ERİK, İshak
AU  - Alpay Karaoğlu, Şengül
AU  - TERZİOĞLU, SALİH
DO  - 10.55730/1300-0527.3430
PY  - 2022
JO  - Turkish Journal of Chemistry
VL  - 46
IS  - 4
SN  - 1300-0527
SP  - 1234
EP  - 1244
DB  - TRDizin
UR  - http://search/yayin/detay/1142007
ER  -