TY  - JOUR
TI  - ISOLATED POLYMYALGIA RHEUMATICA: A CROSS-SECTIONAL, SINGLECENTER, RETROSPECTIVE COHORT STUDY
AB  - Objective: We aimed to review clinical, laboratory findings, disease progression and treatment response in patients with isolated polymyalgia rheumatica (PMR) and to investigate the effect of initial and maintenance corticosteroid dose on the disease progression. Methods: Nineteen isolated PMR patients were included in the study. Demographic data, anthropometric measurements, comorbidities, initial symptom, physical examination, clinical, laboratory findings, medications, changes in treatment status, cumulative corticosteroid dose were recorded. The medical data of first (1st month), second (4th month), third (7th month) visits were noted. Results: The initial corticosteroid dose was 21.5±8.9 mg. While the complaints regarding PMR decreased in 52.6% of patients in the first visit, those complaints regressed in 47.4% and 73.7% of patients in the second and third visit, respectively. In the first visit, the mean erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) values were 21.7±12.3 mm/h and 5.8±5.1 mg/dl. In the second and third visits, while the mean ESR was found as 36.5±27.3 mm/h and 27.3±18.6 mm/h, the mean CRP was 27.2±43.0 mg/dl and 17.6±30.2 mg/dl, respectively. Clinical remission was observed in 47.4% of patients in the second visit and in 31.6% of patients in the third visit. Median cumulative corticosteroid doses were 600 mg in first visit, 960 mg in second visit and 1346 mg in the third visit. Conclusion: The clinical characteristics and the initial corticosteroid dose were compatible with the literature. Even though cumulative corticosteroid doses were quite high, lower remission rates were observed in these patients.
AU  - Cefle, Ayse
AU  - Yazici, Ayten
AU  - Gokcen, Neslihan
AU  - Tuncer Kuru, Fatma
DO  - 10.53446/actamednicomedia.1109338
PY  - 2022
JO  - Acta Medica Nicomedia
VL  - 5
IS  - 3
SN  - 2717-8994
SP  - 181
EP  - 187
DB  - TRDizin
UR  - http://search/yayin/detay/1142052
ER  -