TY  - JOUR
TI  - L-(+)-Tryptophan methyl ester derived polymeric microbeads as an efficient heterogeneous catalyst for green synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3- carbonitriles
AB  - The cross-linked microbeads with average diameter of 106–300 μm, [poly(EGDMA-MATrp)], were obtained by copolymerization reaction of N-methacryloyl-L-(+)-tryptophan methyl ester (MATrp) with ethylene glycol dimethacrylate (EGDMA) and successfully applied as a heterogeneous catalyst in conjugate addition reaction of nitromethane to substituted 2-iminochromenes in aqueous media. A variety of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles has been synthesized in good yields. Polymeric microbeads were very durable and reused 5 times without a significant loss of activity. DFT calculations and experimental results revealed the significant role of π-π interactions as well as hydrogen bonding in the reaction mechanism.
AU  - KOZ, ÖMER
AU  - Kaya, Yunus
AU  - Osman, Bilgen
AU  - HALIÇ, AYSE
AU  - KOZ, GAMZE
DO  - 10.55730/1300-0527.3467
PY  - 2022
JO  - Turkish Journal of Chemistry
VL  - 46
IS  - 5
SN  - 1300-0527
SP  - 1642
EP  - 1650
DB  - TRDizin
UR  - http://search/yayin/detay/1142249
ER  -