CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE
Yıl: 2022 Cilt: 28 Sayı: 3 Sayfa Aralığı: 165 - 171 Metin Dili: İngilizce DOI: 10.5505/tbdhd.2022.25483 İndeks Tarihi: 27-12-2022
CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE
Öz: INTRODUCTION: Certain female sex specific factors (SSFs) including pregnancy, puerperium and oral contraceptive (OC) use have been associated with cerebral venous thrombosis (CVT). We aimed to determine if there are differences between female patients with and without SSFs regarding the clinical characteristics, neuroimaging findings and the prognosis of CVT. METHODS: This is a retrospective study that included consecutive female inpatients with CVT admitted to our hospital between January 1, 2012 and December 31, 2021. The demographic and clinical characteristics, neuroimaging findings and the outcome data were collected from the patient files. RESULTS: Fifty-three female patients were included into the study. Thirty-one (58.5%) of the patients had SSFs including pregnancy (n=2), puerperium (n=20), and OC use (n=9). The mean age of patients with SSFs was lower than that of the patients without SSFs (30.7 and 44.0, respectively, p=0.002). The mode of disease onset, clinical manifestations, epileptic seizures, parenchymal lesions, thrombosed veins, length of hospital stay did not differ between the patients with and without SSFs. Predisposing factors, including cancer, were more common in the patients without SSFs. The median of the modified Ranskin scale score of the patients with SSFs was lower than that of the patients without SSFs. The OC users were older and had a more slow disease onset than the postpartum patients. All patients were treated with anticoagulants, decompressive surgery was performed in one patient. DISCUSSION AND CONCLUSION: The majority of the female CVT patients had SSFs, most commonly puerperium. The mean age is lower and prognosis is better in the patients with SSFs.
Anahtar Kelime: KADIN CINSİYETE ÖZGÜ FAKTÖRLERİ OLAN VE OLMAYAN HASTALARDA SEREBRAL VENÖZ TROMBOZ - TEK MERKEZ DENEYİMİ
Öz: GİRİŞ ve AMAÇ: Gebelik, puerperium ve oral kontraseptif (OK) kullanımından oluşan, kadın cinsiyete özgü faktörler (CÖF) serebral venöz trombozla (SVT) ilişkilendirilmiştir. Bu çalışmada, CÖF’lerine sahip olan ve olmayan kadın SVT hastaları arasında klinik ve nörogörüntüleme özellikleri ve prognoz açısından fark olup olmadığını araştırmayı hedefledik. YÖNTEM ve GEREÇLER: Bu retrospektif çalışmaya, 1 Ocak 2012 ve 31 Aralık 2021 tarihleri arasında kliniğimize başvuran ve hospitalize edilen ardışık kadın SVT hastaları dahil edildi. Demografik ve klinik özellikler, nörogörüntüleme bulguları ve sonlanım verileri hasta dosyalarından elde edildi. BULGULAR: Çalışmaya 53 kadın hasta dahil edildi. Otuz bir hastada (%58,5) CÖF mevcuttu: gebelik (n=2), puerperium (n=20) ve OK kullanımı (n=9). CÖF olan hastaların ortalama yaşı, CÖF olmayan hastalardan daha düşüktü (sırasıyla 30,7 ve 44,0, p=0.002). Hastalık başlangıç şekli, klinik özellikleri epileptik nöbetler, parankimal lezyonlar, tromboze venler ve hospitalizasyon süresi açısından CÖF olan ve olmayan hastalar arasında fark yoktu. Kanser dahil predispozan faktörler CÖF olmayan hastalarda daha sıktı. CÖF olan hastalarda ortanca modifiye Rankin skoru daha düşüktü. OK kullananların yaş ortalaması postpartum hastalardan daha yüksekti ve hastalık başlangıcı daha yavaştı. Tüm hastalar antikoagülanlarla tedavi edildiler, bir hastaya dekompresif cerrahi uygulandı. TARTIŞMA ve SONUÇ: Kadın SVT hastalarının büyük kısmında, en sık puerperium olmak üzere CÖF vardır. CÖF olan hastalarda ortalama yaş daha düşük ve prognoz daha iyidir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | yildiz c, Kayim Yildiz O (2022). CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. , 165 - 171. 10.5505/tbdhd.2022.25483 |
| Chicago | yildiz caglar,Kayim Yildiz Ozlem CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. (2022): 165 - 171. 10.5505/tbdhd.2022.25483 |
| MLA | yildiz caglar,Kayim Yildiz Ozlem CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. , 2022, ss.165 - 171. 10.5505/tbdhd.2022.25483 |
| AMA | yildiz c,Kayim Yildiz O CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. . 2022; 165 - 171. 10.5505/tbdhd.2022.25483 |
| Vancouver | yildiz c,Kayim Yildiz O CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. . 2022; 165 - 171. 10.5505/tbdhd.2022.25483 |
| IEEE | yildiz c,Kayim Yildiz O "CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE." , ss.165 - 171, 2022. 10.5505/tbdhd.2022.25483 |
| ISNAD | yildiz, caglar - Kayim Yildiz, Ozlem. "CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE". (2022), 165-171. https://doi.org/10.5505/tbdhd.2022.25483 |
| APA | yildiz c, Kayim Yildiz O (2022). CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. Türk Beyin Damar Hastalıkları Dergisi, 28(3), 165 - 171. 10.5505/tbdhd.2022.25483 |
| Chicago | yildiz caglar,Kayim Yildiz Ozlem CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. Türk Beyin Damar Hastalıkları Dergisi 28, no.3 (2022): 165 - 171. 10.5505/tbdhd.2022.25483 |
| MLA | yildiz caglar,Kayim Yildiz Ozlem CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. Türk Beyin Damar Hastalıkları Dergisi, vol.28, no.3, 2022, ss.165 - 171. 10.5505/tbdhd.2022.25483 |
| AMA | yildiz c,Kayim Yildiz O CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. Türk Beyin Damar Hastalıkları Dergisi. 2022; 28(3): 165 - 171. 10.5505/tbdhd.2022.25483 |
| Vancouver | yildiz c,Kayim Yildiz O CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE. Türk Beyin Damar Hastalıkları Dergisi. 2022; 28(3): 165 - 171. 10.5505/tbdhd.2022.25483 |
| IEEE | yildiz c,Kayim Yildiz O "CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE." Türk Beyin Damar Hastalıkları Dergisi, 28, ss.165 - 171, 2022. 10.5505/tbdhd.2022.25483 |
| ISNAD | yildiz, caglar - Kayim Yildiz, Ozlem. "CEREBRAL VENOUS THROMBOSIS IN PATEINTS WITH AND WITHOUT FEMALE SPECIFIC SEX FACTORS - A SINGLE-CENTER EXPERIENCE". Türk Beyin Damar Hastalıkları Dergisi 28/3 (2022), 165-171. https://doi.org/10.5505/tbdhd.2022.25483 |
