All aspects of sciatic nerve injection injury: an experiment with 78 rats
Yıl: 2022 Cilt: 52 Sayı: 5 Sayfa Aralığı: 1591 - 1599 Metin Dili: İngilizce DOI: 10.55730/1300-0144.5499 İndeks Tarihi: 27-12-2022
All aspects of sciatic nerve injection injury: an experiment with 78 rats
Öz: Background/aim: In this study, we evaluate sciatic nerve injuries due to intramuscular injections, which is an important medicolegal problem frequently encountered in medical practice, with an extended experimental rat model of peripheral nerve injury. Materials and methods: A total of 78 male Wistar albino rats were divided into five main groups, including a control group, a sham saline group, and groups that received benzathine penicillin G, diclofenac sodium, and dexamethasone, respectively. These pharmaceutical agents were applied to the sciatic nerves of all rats after exploration in the epineurial, endoneurial, and intrafascicular compartments, excluding the control group. Outcomes were evaluated for all rats and their sciatic nerves according to functional, electrophysiological, and histopathological results. Results: Injuries were most evident in the groups that received penicillin G and diclofenac sodium, and this finding was statistically significant. It was also found that endoneurial and intrafascicular injections may cause more harm than epineurial injections. Conclusion: We have demonstrated that any medical injections applied to the epineurial, endoneurial, or intrafascicular compartments of the sciatic nerve may cause functional and electrophysiological loss with or without deterioration of the peripheral nerve architecture.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Zeynal M, Kadioglu H (2022). All aspects of sciatic nerve injection injury: an experiment with 78 rats. , 1591 - 1599. 10.55730/1300-0144.5499 |
| Chicago | Zeynal Mete,Kadioglu Hakan Hadi All aspects of sciatic nerve injection injury: an experiment with 78 rats. (2022): 1591 - 1599. 10.55730/1300-0144.5499 |
| MLA | Zeynal Mete,Kadioglu Hakan Hadi All aspects of sciatic nerve injection injury: an experiment with 78 rats. , 2022, ss.1591 - 1599. 10.55730/1300-0144.5499 |
| AMA | Zeynal M,Kadioglu H All aspects of sciatic nerve injection injury: an experiment with 78 rats. . 2022; 1591 - 1599. 10.55730/1300-0144.5499 |
| Vancouver | Zeynal M,Kadioglu H All aspects of sciatic nerve injection injury: an experiment with 78 rats. . 2022; 1591 - 1599. 10.55730/1300-0144.5499 |
| IEEE | Zeynal M,Kadioglu H "All aspects of sciatic nerve injection injury: an experiment with 78 rats." , ss.1591 - 1599, 2022. 10.55730/1300-0144.5499 |
| ISNAD | Zeynal, Mete - Kadioglu, Hakan Hadi. "All aspects of sciatic nerve injection injury: an experiment with 78 rats". (2022), 1591-1599. https://doi.org/10.55730/1300-0144.5499 |
| APA | Zeynal M, Kadioglu H (2022). All aspects of sciatic nerve injection injury: an experiment with 78 rats. Turkish Journal of Medical Sciences, 52(5), 1591 - 1599. 10.55730/1300-0144.5499 |
| Chicago | Zeynal Mete,Kadioglu Hakan Hadi All aspects of sciatic nerve injection injury: an experiment with 78 rats. Turkish Journal of Medical Sciences 52, no.5 (2022): 1591 - 1599. 10.55730/1300-0144.5499 |
| MLA | Zeynal Mete,Kadioglu Hakan Hadi All aspects of sciatic nerve injection injury: an experiment with 78 rats. Turkish Journal of Medical Sciences, vol.52, no.5, 2022, ss.1591 - 1599. 10.55730/1300-0144.5499 |
| AMA | Zeynal M,Kadioglu H All aspects of sciatic nerve injection injury: an experiment with 78 rats. Turkish Journal of Medical Sciences. 2022; 52(5): 1591 - 1599. 10.55730/1300-0144.5499 |
| Vancouver | Zeynal M,Kadioglu H All aspects of sciatic nerve injection injury: an experiment with 78 rats. Turkish Journal of Medical Sciences. 2022; 52(5): 1591 - 1599. 10.55730/1300-0144.5499 |
| IEEE | Zeynal M,Kadioglu H "All aspects of sciatic nerve injection injury: an experiment with 78 rats." Turkish Journal of Medical Sciences, 52, ss.1591 - 1599, 2022. 10.55730/1300-0144.5499 |
| ISNAD | Zeynal, Mete - Kadioglu, Hakan Hadi. "All aspects of sciatic nerve injection injury: an experiment with 78 rats". Turkish Journal of Medical Sciences 52/5 (2022), 1591-1599. https://doi.org/10.55730/1300-0144.5499 |
