Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species

Ahmet CEYLAN, (Erciyes Üniversitesi, Eczacılık Fakültesi, Farmasötik Biyoteknoloji Anabilim Dalı, Kayseri, Türkiye)
Gökçe ŞEKER KARATOPRAK, (Erciyes Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, Kayseri, Türkiye)
Zekiye KOCAKAYA, (Kayseri Üniversitesi, Safiye Çıkrıkçıoğlu Meslek Yüksekokulu, Bitkisel ve Hayvansal Üretim Bölümü, Kayseri, Türkiye)
Mustafa KOCAKAYA (Yozgat Bozok Üniversitesi, Boğazlıyan Meslek Yüksekokulu, Bitkisel ve Hayvansal Üretim Bölümü, Yozgat, Türkiye)
Cumhuriyet Science Journal
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Yıl: 2022 Cilt: 43 Sayı: 4 Sayfa Aralığı: 550 - 555 Metin Dili: İngilizce DOI: 10.17776/csj.1141849 İndeks Tarihi: 09-01-2023

Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species

Öz:
The present study evaluated the DNA protective properties and antimicrobial activities of the methanol extracts of nine Cladonia species, namely C. pocillum, C. subulata, C. pyxidata, C. coniocraea, C. foliacea, C. firma, C. furcata, C. fimbriata and C. rangiformis collected in Turkey. DNA protection properties efficiency of Cladonia extracts was evaluated using pBR322 plasmid DNA. In vitro antimicrobial activities of methanol extracts against two Gram-negative bacteria (Escherichia coli and Proteus mirabilis), three Gram-positive bacteria (Staphylococcus aureus, Micrococcus luteus and Bacillus subtilis) and two fungal strains (Candida glabrata and Candida albicans) were examined using the disc diffusion method and through the determination of minimal inhibitory concentrations (MIC). DNA protective studies, all Cladonia extracts protected pBR322 plasmid DNA against damage caused by the hydrogen peroxide (H2O2) with ultraviolet (UV). The results demonstrated that the inhibition zones in the disc diffusion method ranged from 6.5 to 19.0 mm. MIC results were ranged from 3.12 to 6.25 mg/mL. Cladonia extracts show a better antimicrobial effect against bacterial strains than fungal strains. The highest antimicrobial effect among lichen species was demonstrated by Cladonia pocillum. Our results demonstrated that tested Cladonia extracts had strong antibacterial and DNA protective effects. This is the first comprehensive study to evaluate the DNA protective properties activity of Cladonia extracts.
Anahtar Kelime: Antimicrobial activity Cladonia DNA protective properties Lichen

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA CEYLAN A, Şeker Karatoprak G, KOCAKAYA Z, kocakaya m (2022). Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. , 550 - 555. 10.17776/csj.1141849
Chicago CEYLAN AHMET,Şeker Karatoprak Gökçe,KOCAKAYA ZEKİYE,kocakaya mustafa Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. (2022): 550 - 555. 10.17776/csj.1141849
MLA CEYLAN AHMET,Şeker Karatoprak Gökçe,KOCAKAYA ZEKİYE,kocakaya mustafa Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. , 2022, ss.550 - 555. 10.17776/csj.1141849
AMA CEYLAN A,Şeker Karatoprak G,KOCAKAYA Z,kocakaya m Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. . 2022; 550 - 555. 10.17776/csj.1141849
Vancouver CEYLAN A,Şeker Karatoprak G,KOCAKAYA Z,kocakaya m Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. . 2022; 550 - 555. 10.17776/csj.1141849
IEEE CEYLAN A,Şeker Karatoprak G,KOCAKAYA Z,kocakaya m "Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species." , ss.550 - 555, 2022. 10.17776/csj.1141849
ISNAD CEYLAN, AHMET vd. "Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species". (2022), 550-555. https://doi.org/10.17776/csj.1141849
APA CEYLAN A, Şeker Karatoprak G, KOCAKAYA Z, kocakaya m (2022). Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. Cumhuriyet Science Journal, 43(4), 550 - 555. 10.17776/csj.1141849
Chicago CEYLAN AHMET,Şeker Karatoprak Gökçe,KOCAKAYA ZEKİYE,kocakaya mustafa Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. Cumhuriyet Science Journal 43, no.4 (2022): 550 - 555. 10.17776/csj.1141849
MLA CEYLAN AHMET,Şeker Karatoprak Gökçe,KOCAKAYA ZEKİYE,kocakaya mustafa Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. Cumhuriyet Science Journal, vol.43, no.4, 2022, ss.550 - 555. 10.17776/csj.1141849
AMA CEYLAN A,Şeker Karatoprak G,KOCAKAYA Z,kocakaya m Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. Cumhuriyet Science Journal. 2022; 43(4): 550 - 555. 10.17776/csj.1141849
Vancouver CEYLAN A,Şeker Karatoprak G,KOCAKAYA Z,kocakaya m Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species. Cumhuriyet Science Journal. 2022; 43(4): 550 - 555. 10.17776/csj.1141849
IEEE CEYLAN A,Şeker Karatoprak G,KOCAKAYA Z,kocakaya m "Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species." Cumhuriyet Science Journal, 43, ss.550 - 555, 2022. 10.17776/csj.1141849
ISNAD CEYLAN, AHMET vd. "Evaluation of DNA Protective and Antimicrobial Properties of some Cladonia Species". Cumhuriyet Science Journal 43/4 (2022), 550-555. https://doi.org/10.17776/csj.1141849
Sayfa Oluşturulma Tarihi
24-04-2024 18:45

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