CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES

Çava, Kutay; YERLİ, Hatice Kübra; aslan, mustafa

doi:10.46519/ij3dptdi.1172937

CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES

Hatice Kübra YERLİ, (Karadeniz Teknik Üniversitesi, Metalurji ve Malzeme Mühendisliği Bölümü, Trabzon, Türkiye)

Kutay Çava, (Karadeniz Teknik Üniversitesi, Tıbbi Cihaz Tasarım ve İmalat Araştırma ve Uygulama Merkezi, Trabzon, Türkiye)

Mustafa ASLAN (Karadeniz Teknik Üniversitesi, Tıbbi Cihaz Tasarım ve İmalat Araştırma ve Uygulama Merkezi, Trabzon, Türkiye)

International Journal of 3D Printing Technologies and Digital Industry

6 1

Yıl: 2022 Cilt: 6 Sayı: 3 Sayfa Aralığı: 540 - 547 Metin Dili: İngilizce DOI: 10.46519/ij3dptdi.1172937 İndeks Tarihi: 11-01-2023

CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES

Öz:

Biomaterials are used in the treatment of advanced orthopedic diseases. Hydroxyapatite (HAp), a bio ceramic material, has an important place in the calcium phosphate family. Since HAp exhibits low mechanical properties, it is used together with polylactic acid (PLA), which has biodegradable properties. In this study, HAp was obtained by the combustion method and its morphological properties were analyzed by scanning electron microscope (SEM) and chemical analyzes by X-ray spectrometry. 3D mechanical test specimens were produced by Fused Deposition Melting (FDM) technique using Hap powder filled PLA filaments. Thermoplastic elastomer (TPE) was used to examine the effect of compatibilizer in PLA-HAp composite materials. Physical, thermal (thermogravemetric analysis, TGA), tensile and compression properties of PLA-HAp composite materials were investigated. Results indicated that TPE improved the interaction between between PLA and HAp powder. With the improved compability the regular distribution of HAp and the interfacial bond in PLA-HAp-TPE composite are better than the other test samples. When the mechanical properties are examined, the tensile and compressive strength values of PLA-HAp-TPE composites are 29.2% and 12.5% higher than those values of PLA-HAp composites, respectively. On the other hand, thermal stability of PLA-HAp-TPE composites composite showed higher thermal stability than those of PLA-HAp composites and gives lower percentage weight loss.

Anahtar Kelime: PLA HAp Physical Mechanical Thermal Properties 3D Printed Samples.

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Navarro, M., Michiardi, A., Castano, O., Planell, J.A., “Biomaterials in orthopaedics”, J R Soc Interface, Vol. 5, Pages 1137–1158, 2008.
2. Takahashi, Y., Yamamoto, M., Tabata Y., “Osteogenic differentiation of mesenchymal stem cells in biodegradable sponges composed of gelatin and β-tricalcium phosphate”, Biomaterials, Vol. 26, Issue 17, Pages 3587–3596, 2005.
3. Fu C., et al. “Antimicrobial silver-HAp composite coatings through two-stage electrochemical synthesis”, Surf Coat Technol, Vol. 301, Pages 13–19, 2016.
4. Dorozhkin, SV., “Calcium orthophosphate deposits: preparation, properties and biomedical applications”. Mater Sci. Eng. C., Vol. 55, Pages 272–326, 2015.
5. Akindoyo, J.O., Beg, M.D.H., Ghazali, S., Heim, H.P., Feldmann, M., “Effects of surface modification on dispersion, mechanical, thermal and dynamic mechanical properties of injection molded PLA-hydroxyapatite composites” Composites: Part A, Vol. 103, Pages 96-105, 2017.
6. Sun, F., Zhou, H., Lee, J., “Various preparation methods of highly porous hydroxyapatite/polymer nanoscale biocomposites for bone regeneration”, Acta Biomater 2011, Vol. 7, Issue 11, Pages 3813–3828, 2011.
7. Auras, R., Lim, L.T., Selk, S.E.M., Tsuji, H. “Polylactic Acid, Synthesis, Structures, Properties, Processing and Applications”, Wıley, NewYork, 2010.
8. Wang, T., Chow, L.C., Frukhtbeyn, S.A., Ting, A.H., Dong, Q., Yang, M., Mitchell, J.W., “Improve the strength of PLA-HA composite through the use of surface initiated polymerization and phosphonic acid coupling agent”, Journal of Research of the National Institute of Standards and Technology, Vol. 116 Issue 5, Pages 785–796, 2011.
9. Reverchon, E., Pisanti, P., Cardea, S., “Nanostructured pllahydroxyapatite scaffolds produced by a supercritical assisted technique”, Industrial and Engineering Chemistry Research, Vol.48, Issue 11, Pages 5310-5316, 2009.
10. Talal, A., McKay, I., Tanner K., Hughes, F.J., “Effects of hydroxyapatite and PDGF concentrations on osteoblast growth in a nanohydroxyapatite-polylactic acid composite for guided tissue regeneration" Journal of Materials Science: Materials in Medicine, Vol. 24, Issue 9, Pages 2211-2221, 2013.
11. Cui, Y., Liu, Y., Cui, Y., Jing, X., Zhang, P., Chen, X., “The nanocomposite scaffold of polylactide-co-glycolide and hydroxyapatite surface-grafted with l-lactic acid oligomer for bone repair”, Acta Biomaterialia, Vol. 5 Issıe 7, Pages 2680–2692, 2009.
12. Baird, D.G., “Polimer İşleme, Fiziksel Bilim ve Teknoloji Ansiklopedisi”, Üçüncü Baskı, 2003.
13. Hoy, M.B., “3D printing: making things at the library”, Med. Ref. Serv. Q., Vol. 32, Pages, 94–99, 2013.
14. Esposito, C.C., Gervaso, F., Scalera, F., Montagna, F., Maiullaro, T., Maffezzoli, S.A., “3D printing of hydroxyapatite polymer-based composites for bone tissue engineering”, J. Polym. Eng. Vol. 37, Pages 741–746, 2017.
15. Youssef, A., Hollister, S.J., Dalton, P.D., “Additive manufacturing of polymer melts for implantable medical devices and scaffolds”, Biofabrication, Vol. 9, Pages 1-29, 2017.
16. Wu, D., Spanou, A., Diez-Escuder, A., Persson, C., “3D-printed PLA HA composite structures as synthetic trabecular bone: A feasibility study using fused deposition modeling”, Journal of the mechanical behavior of biomedical materials, Vol. 103, Issue 103608, Pages 1-10, 2020.
17. Rizzi, S.C., Heath, D., Coombes, A., Bock, N., Textor, M., Downes, S., “Biodegradable polymer hydroxyapatite composites: Surface analysis and initial attachment of human osteoblasts” J. Biomed. Mater. Res., Vol. 55, Pages 475 482, 2001.
18. Wang, H., Li, Y., Zuo, Y., Li J., Ma, S., Cheng, L., “Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite polyamide composite scaffolds for bone tissue engineering”, Biomaterials, Vol. 28, Pages 3338–3348, 2007.
19. Khoo, W., Nor, F.M., Ardhyananta, H., Kurniawan, D., “Preparation of Natural Hydroxyapatite from Bovine Femur Bones Using Calcination at Various Temperatures” 2nd. International Materials Industrial and Manufacturing Engineering Conference, MIMEC2015, Procedia Manufacturing, Vol. 2, Pages 196 – 201, 2015.
20. Mahmud, K., Azharul Islam, M.D., Mitsionis, A., Albanis, T., Vaimakis, T., “Adsorption of direct yellow 27 from water by poorly crystalline hydroxyapatite prepared via precipitation method” Desalination and Water Treatment, Vol.41, Issue 1-3, Pages 170-178, 2012.
21. Yee, Y.Y., Ching, Y.C., Rozali, S., Hashim, N.A., Singh, R. “Preparation and characterization of poly (lactic acid)-based composites reinforced with poly dimethyl siloxane/ultrasound-treated oil palm empty fruit bunch” Polymer Technology Engineering, Vol. 54, Issue 13, Pages 1321–33, 2015.
22. Oguz, H., Dogan, C., Kara, D., Ozen, Z. T., Oavli, D. and Nofar, M., “Development of PLA-PBAT and PLA-PBSA bio-blends: Effects of processing type and PLA crystallinity on morphology and mechanical properties”, A.I.P. Conference Proceedings 2055, 030003 January 2019.

APA	YERLİ H, Çava K, aslan m (2022). CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. , 540 - 547. 10.46519/ij3dptdi.1172937
Chicago	YERLİ Hatice Kübra,Çava Kutay,aslan mustafa CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. (2022): 540 - 547. 10.46519/ij3dptdi.1172937
MLA	YERLİ Hatice Kübra,Çava Kutay,aslan mustafa CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. , 2022, ss.540 - 547. 10.46519/ij3dptdi.1172937
AMA	YERLİ H,Çava K,aslan m CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. . 2022; 540 - 547. 10.46519/ij3dptdi.1172937
Vancouver	YERLİ H,Çava K,aslan m CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. . 2022; 540 - 547. 10.46519/ij3dptdi.1172937
IEEE	YERLİ H,Çava K,aslan m "CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES." , ss.540 - 547, 2022. 10.46519/ij3dptdi.1172937
ISNAD	YERLİ, Hatice Kübra vd. "CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES". (2022), 540-547. https://doi.org/10.46519/ij3dptdi.1172937

APA	YERLİ H, Çava K, aslan m (2022). CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. International Journal of 3D Printing Technologies and Digital Industry, 6(3), 540 - 547. 10.46519/ij3dptdi.1172937
Chicago	YERLİ Hatice Kübra,Çava Kutay,aslan mustafa CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. International Journal of 3D Printing Technologies and Digital Industry 6, no.3 (2022): 540 - 547. 10.46519/ij3dptdi.1172937
MLA	YERLİ Hatice Kübra,Çava Kutay,aslan mustafa CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. International Journal of 3D Printing Technologies and Digital Industry, vol.6, no.3, 2022, ss.540 - 547. 10.46519/ij3dptdi.1172937
AMA	YERLİ H,Çava K,aslan m CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. International Journal of 3D Printing Technologies and Digital Industry. 2022; 6(3): 540 - 547. 10.46519/ij3dptdi.1172937
Vancouver	YERLİ H,Çava K,aslan m CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES. International Journal of 3D Printing Technologies and Digital Industry. 2022; 6(3): 540 - 547. 10.46519/ij3dptdi.1172937
IEEE	YERLİ H,Çava K,aslan m "CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES." International Journal of 3D Printing Technologies and Digital Industry, 6, ss.540 - 547, 2022. 10.46519/ij3dptdi.1172937
ISNAD	YERLİ, Hatice Kübra vd. "CHARACTERISATION OF 3D PRINTED HYDROXYAPITATE POWDER (HAp) FILLED POLYLACTIC ACID (PLA) COMPOSITES". International Journal of 3D Printing Technologies and Digital Industry 6/3 (2022), 540-547. https://doi.org/10.46519/ij3dptdi.1172937