TY  - JOUR
TI  - Investigation of the relationship between placenta trace element levels and methylated arginines
AB  - Aim: Environmental exposure and maternal nutrition are vital for placental and fetal development during pregnancy. Essential elements such as zinc, copper and selenium are important elements that are needed for human growth and development. Research indicates that methylated arginines play a key role in pregnancy and offspring outcomes. The aim of the study was to compare the placental tissue levels of trace elements and methylated arginines. In addition, we aimed to evaluate this placental trace elements and methylated arginine levels in terms of placental and birth weight. Material and Method: This is a case-control study with 133 pregnant women. Two groups were formed: women with higher risk of exposure to chemicals (working in chemistry, metal and other industrial sectors) and those with no risk of exposure to hazardous chemicals (house wives and working in other non-hazardous workplaces). Placenta zinc, copper and selenium and asymmetric dimethylarginine, symmetric dimethylarginine, arginine, citrulline, homoarginine and L-N-monomethyl arginine levels were investigated. Results: There was a positive correlation between birth weight with copper, L-N-monomethyl arginine, total methylarginines; there was a negative relationship between birth weight and asymmetric dimethylarginine, symmetric dimethylarginine, arginine, citrulline. However, no statistically significant relationship was found between trace elements such as zinc, copper and selenium with methylated arginines, except for L-N-monomethyl arginine (r=0.178; p<0.05). Conclusion: Zinc, copper and selenium levels are not related to processes that reduce birth weight and vascular factors.
AU  - TUTKUN, Lütfiye
AU  - Hocaoglu, Asım
AU  - SİMSİR, COSKUN
AU  - alagüney, mehmet
AU  - öztan, özgür
AU  - Deniz, Serdar
AU  - TURKSOY, Vugar Ali
DO  - 10.32322/jhsm.962489
PY  - 2021
JO  - Journal of  health sciences and medicine (Online)
VL  - 4
IS  - 5
SN  - 2636-8579
SP  - 746
EP  - 751
DB  - TRDizin
UR  - http://search/yayin/detay/1154687
ER  -