Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.

kabadere, selda; UYAR, Ruhi; SAVAROĞLU, Filiz; İlhan, Semra; FİLİK İŞÇEN, Cansu; VATAN, Ayşe Pınar Öztopcu

Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.

Filiz SAVAROĞLU, (Eskişehir Osmangazi Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Eskişehir, Türkiye)

Cansu FİLİK İŞÇEN, (Eskişehir Osmangazi Üniversitesi, Fen Edebiyat Fakültesi, Eğitim Bölümü, Eskişehir, Türkiye)

Ayşe Pınar Öztopcu VATAN, (Eskişehir Osmangazi Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Eskişehir, Türkiye)

Selda KABADERE, (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Eskişehir, Türkiye)

Semra İLHAN, (Eskişehir Osmangazi Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Bölümü, Eskişehir, Türkiye)

Ruhi UYAR (Eskişehir Osmangazi Üniversitesi, Tıp Fakültesi, Fizyoloji Anabilim Dalı, Eskişehir, Türkiye)

Turkish Journal of Biology

6 0

Yıl: 2011 Cilt: 35 Sayı: 3 Sayfa Aralığı: 361 - 369 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.

Öz:

The purpose of the current study was to investigate the possible antimicrobial and anticancer properties of theaquatic moss Fontinalis antipyretica Hedw. (Fontinalaceae). We first obtained 8 different extracts (methanol; chloroform;acetone; ethyl acetate A, B, C, and D) by two dif erent extraction processes. The antimicrobial activity of these extractswas then assessed by using the well diffusion method against 8 bacterial and 7 fungal strains. The results of antimicrobialstudies showed that extracts of chloroform, acetone, and ethyl acetate A and C were active against almost all the speciestested. The most effective extract was C, which was then screened through a preparative TLC (bioautography) for itsactive components. Spot 4 of extract C exhibited the highest antimicrobial activity against 5 bacterial strains (B. cereus,B. subtilis, E. faecalis, E. aerogenes, and Y. enterocolitica) and 3 fungal strains (A. l avus, F. solani, and F. g raminearum),with MIC values of 93.8-375.0 μg/mL and 187.5-375.0 μg/mL, respectively. In addition, in vitro toxicity of the activecomponent of extract C at the concentrations of 0.16, 1.6, 16, 80, and 160 μg/mL was tested. Depending on dose andtime, only 80 and 160 μg/mL decreased rat glioma (C6) cell viability at er 24 or 48 h. The present study suggests thepossibility that Fontinalis antipyretica possesses antimicrobial and anticancer agent(s)

Anahtar Kelime: mosses toxicity antineoplastic agents Bryophyta antifungal properties antibacterial properties aquatic plants plant extracts

Konular: Biyoloji

Sucul karayosunu Fontinalis antipyretica Hedw.’ nin antimikrobiyal ve antikanser aktivitesinin belirlenmesi

Öz:

Anahtar Kelime: antifungal özellikler antibakteriyel özellikler sucul bitkiler bitki özütü karayosunu toksisite antineoplastik ajanlar Bryophyta

Konular: Biyoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SAVAROĞLU F, FİLİK İŞÇEN C, VATAN A, kabadere s, İlhan S, UYAR R (2011). Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. , 361 - 369.
Chicago	SAVAROĞLU Filiz,FİLİK İŞÇEN Cansu,VATAN Ayşe Pınar Öztopcu,kabadere selda,İlhan Semra,UYAR Ruhi Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. (2011): 361 - 369.
MLA	SAVAROĞLU Filiz,FİLİK İŞÇEN Cansu,VATAN Ayşe Pınar Öztopcu,kabadere selda,İlhan Semra,UYAR Ruhi Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. , 2011, ss.361 - 369.
AMA	SAVAROĞLU F,FİLİK İŞÇEN C,VATAN A,kabadere s,İlhan S,UYAR R Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. . 2011; 361 - 369.
Vancouver	SAVAROĞLU F,FİLİK İŞÇEN C,VATAN A,kabadere s,İlhan S,UYAR R Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. . 2011; 361 - 369.
IEEE	SAVAROĞLU F,FİLİK İŞÇEN C,VATAN A,kabadere s,İlhan S,UYAR R "Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.." , ss.361 - 369, 2011.
ISNAD	SAVAROĞLU, Filiz vd. "Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.". (2011), 361-369.

APA	SAVAROĞLU F, FİLİK İŞÇEN C, VATAN A, kabadere s, İlhan S, UYAR R (2011). Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. Turkish Journal of Biology, 35(3), 361 - 369.
Chicago	SAVAROĞLU Filiz,FİLİK İŞÇEN Cansu,VATAN Ayşe Pınar Öztopcu,kabadere selda,İlhan Semra,UYAR Ruhi Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. Turkish Journal of Biology 35, no.3 (2011): 361 - 369.
MLA	SAVAROĞLU Filiz,FİLİK İŞÇEN Cansu,VATAN Ayşe Pınar Öztopcu,kabadere selda,İlhan Semra,UYAR Ruhi Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. Turkish Journal of Biology, vol.35, no.3, 2011, ss.361 - 369.
AMA	SAVAROĞLU F,FİLİK İŞÇEN C,VATAN A,kabadere s,İlhan S,UYAR R Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. Turkish Journal of Biology. 2011; 35(3): 361 - 369.
Vancouver	SAVAROĞLU F,FİLİK İŞÇEN C,VATAN A,kabadere s,İlhan S,UYAR R Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.. Turkish Journal of Biology. 2011; 35(3): 361 - 369.
IEEE	SAVAROĞLU F,FİLİK İŞÇEN C,VATAN A,kabadere s,İlhan S,UYAR R "Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.." Turkish Journal of Biology, 35, ss.361 - 369, 2011.
ISNAD	SAVAROĞLU, Filiz vd. "Determination of antimicrobial and antiproliferative activities of the aquatic moss Fontinalis antipyretica Hedw.". Turkish Journal of Biology 35/3 (2011), 361-369.