Assessment of serum galectin-3 levels in acute rheumatic fever

Epçaçan, Serdar; RAMOĞLU, Mehmet Gökhan; Karakuş Epçaçan, Zerrin; BASKIN, A.Kubra

doi:10.24953/turkjped.2022.79

Assessment of serum galectin-3 levels in acute rheumatic fever

Serdar EPCACAN, (Sağlık Bilimleri Üniversitesi, Van Eğitim ve Araştırma Hastanesi, Çocuk Kardiyolojisi Bölümleri, Van, Türkiye)

Mehmet RAMOĞLU, (Ankara Üniversitesi, Tıp Fakültesi, Çocuk Kardiyolojisi Anabilim Dalı, Ankara, Türkiye)

Zerrin Karakuş Epçaçan, (Sağlık Bilimleri Üniversitesi, Van Eğitim ve Araştırma Hastanesi, Çocuk Hastalıkları Kliniği, Van, Türkiye)

Avniye Kübra Baskın (Sağlık Bilimleri Üniversitesi, Van Eğitim ve Araştırma Hastanesi, Çocuk Allerji ve İmmünoloji Bölümleri, Van, Türkiye)

Turkish Journal of Pediatrics

4 0

Yıl: 2022 Cilt: 64 Sayı: 6 Sayfa Aralığı: 1050 - 1057 Metin Dili: İngilizce DOI: 10.24953/turkjped.2022.79 İndeks Tarihi: 09-02-2023

Assessment of serum galectin-3 levels in acute rheumatic fever

Öz:

Background. Galectin-3 is a biomarker which takes a role in both acute and chronic inflammation as well as fibrosis and oxidative stress. Increased levels of it are associated with cardiovascular diseases. This study was performed to investigate the levels of galectin-3 in acute rheumatic fever (ARF). Methods. 30 patients with ARF and 26 healthy children were included. Galectin-3 levels of the patients were compared with the controls, as well as within the patients before and after the treatment. Results. The patients had significantly lower galectin-3 levels on admission than the control (p=0.02), but its levels were not significantly different between these groups at the end of treatment (p=0.714). The mean galectin-3 levels of the patients were increased after the treatment (p<0.001). Severity of carditis and galectin-3 levels were negatively correlated (r=-539, p=0.02). Conclusions. Children with ARF have significantly reduced levels of galectin-3 and there is a negative correlation between the severity of the carditis and galectin-3 levels. Studies with larger sample sizes may give more accurate data about the role of galectin-3 in ARF.

Anahtar Kelime: galectin-3 acute rheumatic fever children.

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Epçaçan S, RAMOĞLU M, Karakuş Epçaçan Z, BASKIN A (2022). Assessment of serum galectin-3 levels in acute rheumatic fever. , 1050 - 1057. 10.24953/turkjped.2022.79
Chicago	Epçaçan Serdar,RAMOĞLU Mehmet Gökhan,Karakuş Epçaçan Zerrin,BASKIN A.Kubra Assessment of serum galectin-3 levels in acute rheumatic fever. (2022): 1050 - 1057. 10.24953/turkjped.2022.79
MLA	Epçaçan Serdar,RAMOĞLU Mehmet Gökhan,Karakuş Epçaçan Zerrin,BASKIN A.Kubra Assessment of serum galectin-3 levels in acute rheumatic fever. , 2022, ss.1050 - 1057. 10.24953/turkjped.2022.79
AMA	Epçaçan S,RAMOĞLU M,Karakuş Epçaçan Z,BASKIN A Assessment of serum galectin-3 levels in acute rheumatic fever. . 2022; 1050 - 1057. 10.24953/turkjped.2022.79
Vancouver	Epçaçan S,RAMOĞLU M,Karakuş Epçaçan Z,BASKIN A Assessment of serum galectin-3 levels in acute rheumatic fever. . 2022; 1050 - 1057. 10.24953/turkjped.2022.79
IEEE	Epçaçan S,RAMOĞLU M,Karakuş Epçaçan Z,BASKIN A "Assessment of serum galectin-3 levels in acute rheumatic fever." , ss.1050 - 1057, 2022. 10.24953/turkjped.2022.79
ISNAD	Epçaçan, Serdar vd. "Assessment of serum galectin-3 levels in acute rheumatic fever". (2022), 1050-1057. https://doi.org/10.24953/turkjped.2022.79

APA	Epçaçan S, RAMOĞLU M, Karakuş Epçaçan Z, BASKIN A (2022). Assessment of serum galectin-3 levels in acute rheumatic fever. Turkish Journal of Pediatrics, 64(6), 1050 - 1057. 10.24953/turkjped.2022.79
Chicago	Epçaçan Serdar,RAMOĞLU Mehmet Gökhan,Karakuş Epçaçan Zerrin,BASKIN A.Kubra Assessment of serum galectin-3 levels in acute rheumatic fever. Turkish Journal of Pediatrics 64, no.6 (2022): 1050 - 1057. 10.24953/turkjped.2022.79
MLA	Epçaçan Serdar,RAMOĞLU Mehmet Gökhan,Karakuş Epçaçan Zerrin,BASKIN A.Kubra Assessment of serum galectin-3 levels in acute rheumatic fever. Turkish Journal of Pediatrics, vol.64, no.6, 2022, ss.1050 - 1057. 10.24953/turkjped.2022.79
AMA	Epçaçan S,RAMOĞLU M,Karakuş Epçaçan Z,BASKIN A Assessment of serum galectin-3 levels in acute rheumatic fever. Turkish Journal of Pediatrics. 2022; 64(6): 1050 - 1057. 10.24953/turkjped.2022.79
Vancouver	Epçaçan S,RAMOĞLU M,Karakuş Epçaçan Z,BASKIN A Assessment of serum galectin-3 levels in acute rheumatic fever. Turkish Journal of Pediatrics. 2022; 64(6): 1050 - 1057. 10.24953/turkjped.2022.79
IEEE	Epçaçan S,RAMOĞLU M,Karakuş Epçaçan Z,BASKIN A "Assessment of serum galectin-3 levels in acute rheumatic fever." Turkish Journal of Pediatrics, 64, ss.1050 - 1057, 2022. 10.24953/turkjped.2022.79
ISNAD	Epçaçan, Serdar vd. "Assessment of serum galectin-3 levels in acute rheumatic fever". Turkish Journal of Pediatrics 64/6 (2022), 1050-1057. https://doi.org/10.24953/turkjped.2022.79