Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode

kılıç, esma; Öztürk, Funda; YÜKSEL, ELİF; Erden, Pınar Esra

doi:10.55730/1300-0527.3523

Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode

Funda ÖZTÜRK, (Tekirdağ Namık Kemal Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü, Tekirdağ, Türkiye)

Elif YÜKSEL, (Tekirdağ Namık Kemal Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü, Tekirdağ, Türkiye)

Pınar Esra ERDEN, (Ankara Hacı Bayram Veli Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü, Ankara, Türkiye)

Esma KILIÇ (Ankara Üniversitesi, Fen Fakültesi, Kimya Bölümü, Ankara, Türkiye)

Turkish Journal of Chemistry

7 0

Yıl: 2023 Cilt: 47 Sayı: 1 Sayfa Aralığı: 126 - 136 Metin Dili: İngilizce DOI: 10.55730/1300-0527.3523 İndeks Tarihi: 13-03-2023

Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode

Öz:

The electrochemical oxidation of aripiprazole was explored at a carbon paste electrode modified with aluminium oxide nanoparticles by cyclic voltammetry and square-wave anodic adsorptive stripping voltammetry. Experimental parameters such as carbon paste composition, scan rate, buffer pH, accumulation time, and accumulation potential were optimized in order to obtain high analytical performance. The incorporation of aluminium oxide nanoparticles into the carbon paste matrix enhanced the effective surface area of the carbon paste electrode and improved the sensitivity. On the aluminium oxide nanoparticles modified carbon paste electrode, aripiprazole exhibited an irreversible anodic peak at +1.17 V in pH 1.8 BR buffer solution. Under optimum conditions, the peak current exhibited a linear dependence with aripiprazole concentration between 0.03 and 8.0 μM with a detection limit of 0.006 μM. The analytical applicability of the voltammetric method was evaluated by quantification of ARP in human serum samples and pharmaceutical formulations.

Anahtar Kelime: Aripiprazole square wave voltammetry aluminium oxide nanoparticles carbon paste electrode pharmaceutical formulation biological fluid

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Öztürk F, YÜKSEL E, Erden P, kılıç e (2023). Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. , 126 - 136. 10.55730/1300-0527.3523
Chicago	Öztürk Funda,YÜKSEL ELİF,Erden Pınar Esra,kılıç esma Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. (2023): 126 - 136. 10.55730/1300-0527.3523
MLA	Öztürk Funda,YÜKSEL ELİF,Erden Pınar Esra,kılıç esma Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. , 2023, ss.126 - 136. 10.55730/1300-0527.3523
AMA	Öztürk F,YÜKSEL E,Erden P,kılıç e Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. . 2023; 126 - 136. 10.55730/1300-0527.3523
Vancouver	Öztürk F,YÜKSEL E,Erden P,kılıç e Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. . 2023; 126 - 136. 10.55730/1300-0527.3523
IEEE	Öztürk F,YÜKSEL E,Erden P,kılıç e "Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode." , ss.126 - 136, 2023. 10.55730/1300-0527.3523
ISNAD	Öztürk, Funda vd. "Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode". (2023), 126-136. https://doi.org/10.55730/1300-0527.3523

APA	Öztürk F, YÜKSEL E, Erden P, kılıç e (2023). Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. Turkish Journal of Chemistry, 47(1), 126 - 136. 10.55730/1300-0527.3523
Chicago	Öztürk Funda,YÜKSEL ELİF,Erden Pınar Esra,kılıç esma Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. Turkish Journal of Chemistry 47, no.1 (2023): 126 - 136. 10.55730/1300-0527.3523
MLA	Öztürk Funda,YÜKSEL ELİF,Erden Pınar Esra,kılıç esma Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. Turkish Journal of Chemistry, vol.47, no.1, 2023, ss.126 - 136. 10.55730/1300-0527.3523
AMA	Öztürk F,YÜKSEL E,Erden P,kılıç e Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. Turkish Journal of Chemistry. 2023; 47(1): 126 - 136. 10.55730/1300-0527.3523
Vancouver	Öztürk F,YÜKSEL E,Erden P,kılıç e Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode. Turkish Journal of Chemistry. 2023; 47(1): 126 - 136. 10.55730/1300-0527.3523
IEEE	Öztürk F,YÜKSEL E,Erden P,kılıç e "Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode." Turkish Journal of Chemistry, 47, ss.126 - 136, 2023. 10.55730/1300-0527.3523
ISNAD	Öztürk, Funda vd. "Electrochemical determination of aripiprazole based on aluminium oxide nanoparticles modified carbon paste electrode". Turkish Journal of Chemistry 47/1 (2023), 126-136. https://doi.org/10.55730/1300-0527.3523