EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM
Yıl: 2023 Cilt: 30 Sayı: 1 Sayfa Aralığı: 97 - 105 Metin Dili: İngilizce DOI: 10.17343/sdutfd.1229962 İndeks Tarihi: 22-03-2023
EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM
Öz: Objective To investigate the success of imaging methods and the effect of preoperative findings on postoperative results in patients who underwent surgery for primary hyperparathyroidism (p-HPT). Material and Method In this study, the data of 50 consecutive patients who underwent p-HPT surgery at the General Surgery Clinic of Yuzuncu Yil University Faculty of Medicine between January 2008 and December 2010 were prospectively analyzed. During the study period, the patients’ demographic data, clinical findings, preoperative and postoperative laboratory results, findings of ultrasonography, scintigraphy, and computed tomography performed for localization in the preoperative period, and surgery and pathology reports were evaluated and recorded. The obtained data were statistically analyzed. Results Musculoskeletal pain was the most common (80%) reason for the patients’ presentation to the hospital. In the operated patients, the serum parathormone and calcium levels significantly decreased compared to the preoperative period (p
Anahtar Kelime: PRİMER HİPERPARATİROİDİ CERRAHİSİ GEÇİREN HASTALARDA PREOPERATİF VE PEROPERATİF PARAMETRELERİN KARŞILAŞTIRILMASI, PREOPERATİF PARAMETRELERİN POSTOPERATİF SEYRİ ÜZERİNE ETKİSİ
Öz: Amaç Çalışmamızda, primer hiperparatiroidi (p-HPT) nedeni ile opere edilen hastalarda görüntüleme yöntemlerinin başarısı ve preoperatif bulguların postoperatif sonuçlara etkisi araştırıldı. Gereç ve Yöntem Bu çalışmada Ocak 2008 ile Aralık 2010 tarihleri arasında Yüzüncü Yıl Üniversitesi Tıp Fakültesi Genel Cerrahi kliniği tarafından p-HPT nedeni ile opere edilen 50 ardışık olgunun verileri prospektif olarak incelendi. Çalışma süresi boyunca hastaların demografik verileri, klinik bulguları, ameliyat öncesi ve sonrası laboratuvar sonuçları, ameliyat öncesi dönemde lokalizasyon amacıyla yapılan ultrasonografi (USG), sintigrafi ve bilgisayarlı tomografi (BT) bulguları, ameliyat ve patoloji raporları incelendi ve kaydedildi. Elde edilen veriler istatistiksel olarak analiz edildi. Bulgular Kas iskelet sistemi ağrılarının en sık (%80) hastaneye başvuru nedeni olduğu görüldü. Opere edilen hastalarda ameliyat sonrası serum parathormon (PTH) ve kalsiyum seviyelerinin ameliyat öncesi döneme göre anlamlı oranda düştüğü tespit edildi (p
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- 1. Silverberg SJ BJ. The Parathyroids: Basic and Clinical Concepts. Orlando, ABD; 2001. 349–60.
- 2. Uruno T, Kebebew E. How to localize parathyroid tumors in primary hyperparathyroidism? J Endocrinol Invest. 2006; 29(9):840-7.
- 3. Wells SA, Debendetti MK DG. Recurrent or persistent hyperparathyroidism. J Bone Min Res. 2002;158–62.
- 4. Rodriquez JM, Tezelman S, Siperstein AE, Duh QY, Higgins C, Morita E, Dowd CF CO. Localization procedures in patients with persistent or recurrent hyperparathyroidism. Arch Surg. 1994, 129(8):870-5.
- 5. Mitchell BK, Kinder BK, Merrell RC. Localization Studies in Patients with Hyperparathyroidism. Surg Clin North Am. 1995; 75(3):483–98.
- 6. Mariani G1, Gulec SA, Rubello D, Boni G, Puccini M, Pelizzo MR, Manca G, Casara D, Sotti G, Erba P, Volterrani D GA. Preoperative localization and radioguided parathyroid surgery. J Nucl Med. 1995;1443–58.
- 7. Frasoldati A, Valcavi R. Challenges in neck ultrasonography: Lymphadenopathy and parathyroid glands. Endocrine Practice. 2004, 10(3):261-8.
- 8. Scheiner JD, Dupuy DE, Monchik JM, Noto RB, Cronan JJ. Pre-operative localization of parathyroid adenomas: A comparison of power and colour Doppler ultrasonography with nuclear medicine scintigraphy. Clin Radiol. 2001; 56(12):984-8.
- 9. Ohe MN, Santos RO, Barros ER, Lage A, Kunii IS, Abrahão M, et al. Changes in clinical and laboratory findings at the time of diagnosis of primary hyperparathyroidism in a University Hospital in São Paulo from 1985 to 2002. Brazilian J Med Biol Res. 2005; 38(9):1383–7.
- 10. Bilezikian JP, Brandi ML, Rubin M, Silverberg SJ. Primary hyperparathyroidism: New concepts in clinical, densitometric and biochemical features. Journal of Internal Medicine. 2005, 257(1):6-17.
- 11. Sywak MS, Knowlton ST, Pasieka JL, Parsons LL, Jones J. Do the National Institutes of Health consensus guidelines for parathyroidectomy predict symptom severity and surgical outcome in patients with primary hyperparathyroidism? Surgery, 2002; 132(6): 1013–20.
- 12. Suliburk JW, Perrier ND. Primary hyperparathyroidism. Oncologist. 2007 Jun;12(6):644-53.
- 13. Silverberg SJ BJ. Principles and Practice of Endocrinology and Metabolism Primary hyperparathyroidism. Philadelphia: Lippincott Willliams & Wilkins; 2001. 564–573 p.
- 14. Bussey AD, Bruder JM. Urinary calcium excretion in primary hyperparathyroidism: Relationship to 25-hydroxyvitamin d status. Endocr Pract. 2005 Jan;11(1):37–42.
- 15. Livolsi VA. Parathyroids IN: Bilezikian JP, Marcus R LM (Eds). The Parathyroids Basic and Clinical Concepts Orlando: Acad Press; 2001;4–10.
- 16. Denham DW, Norman J. Cost-effectiveness of preoperative sestamibi scan for primary hyperparathyroidism is dependent solely upon the surgeon’s choice of operative procedure. J Am Coll Surg. 1998; 186(3):293-305.
- 17. Tziakouri C, Eracleous E, Skannavis S, Pierides A, Symeonides P, Gourtsoyiannis N. Value of Ultrasonography, CT and MR Imaging in the Diagnosis of Primary Hyperparathyroidism. Acta radiol. 1996 May;37(3P2):720–6.
- 18. Gofrit ON, Lebensart PD, Pikarsky A, Lackstein D, Gross DJ, Shiloni E. High-resolution ultrasonography: Highly sensitive, specific technique for preoperative localization of parathyroid adenoma in the absence of multinodular thyroid disease. World J Surg. 1997; 21(3):287-91
- 19. Chapuis Y, Fulla Y, Bonnichon P, Tarla E, Abboud B, Pitre J, et al. Values of ultrasonography, sestamibi scintigraphy, and intraoperative measurement of 1-84 PTH for unilateral neck exploration of primary hyperparathyroidism. World Journal of Surgery. 1996. 20(7):835-40
- 20. Mazzeo S, Caramella D, Lencioni R, Molea N, De Liperi A, Marcocci C, et al. Comparison among sonography, double-tracer subtraction scintigraphy, and double-phase scintigraphy in the detection of parathyroid lesions. Am J Roentgenol. 1996; 166(6):1465-70.
- 21. De Feo ML, Colagrande S, Biagini C, Tonarelli A, Bisi G, Vaggelli L, et al. Parathyroid glands: Combination of 99mTc MIBI scintigraphy and US for demonstration of parathyroid glands and nodules. Radiology. 2000; 214(2):393-402.
- 22. Brennan MF, Doppman JL, Kurdy AG, Marx SJ, Spiegel AM, Aurbach GD. Assessment of techniques for preoperative parathyroid gland localization in patients undergoing reoperation for hyperparathyroidism. Surgery. 1982; 91(1):6-11.
- 23. Lo CY, van Heerden JA P reoperations. Textbook of Endocrine Surgery. Philadelphia: Saunders; 2005. 418–525
- 24. Gaz RD. Surgery of the Thyroid and Parathyroid Glands. Philadelphia: Saunders; 2003. 564–570
- 25. De Beur SMJ, Streeten EA LM. Principles and Practice of Endocrinology and Metabolism. Philadelphia: Lippincott Williams&Wilkins; 2001. 586–602 p.
- 26. Pavlov A V. Regeneration of the parathyroid glands after partial resection. Arkh Anat Gistol Embriol. 1986; 77-80.
- 27. Parfitt AM. Parathyroid growth: The Parathyroids: Basic and Clinical Concepts. NewYork: Raven Press; 1994. 373–405 p.
- 28. Mallette LE, Bilezikian JP, Heath DA AG. Manual of Endocrine Surgery. 1974. 127–146 p.
- 29. Rao SD, Honasoge MD, Divine GW, Phillips ER, Lee MW, Ansari MR, Talpos GB PA. Effect of vitamin D nutrition on parathyroid adenoma weight: Pathogenetic and clinical implications. J Clin Endocrinol Metab. 2000; 85(3), 1054–8.
- 30. Kösem M, Algün E, Kotan Ç, Harman M, Öztürk M. Coexistent thyroid pathologies and high rate of papillary cancer in patients with primary hyperparathyroidism: Controversies about minimal invasive parathyroid surgery. Acta Chir Belg. 2004; 104(5):568-71
- 31. Gul K, Ozdemir D, Korukluoglu B, Ersoy PE, Aydin R, Ugras SN, et al. Preoperative and postoperative evaluation of thyroid disease in patients undergoing surgical treatment of primary hyperparathyroidism. Endocr Pract. 2010; 16(1):7-13.
- 32. Monroe DP, Edeiken-Monroe BS, Lee JE, Evans DB, Perrier ND. Impact of preoperative thyroid ultrasonography on the surgical management of primary hyperparathyroidism. Br J Surg. 2008; 95(8):957-60.
| APA | HASIRCI I, kotan ç (2023). EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. , 97 - 105. 10.17343/sdutfd.1229962 |
| Chicago | HASIRCI ISMAIL,kotan çetin EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. (2023): 97 - 105. 10.17343/sdutfd.1229962 |
| MLA | HASIRCI ISMAIL,kotan çetin EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. , 2023, ss.97 - 105. 10.17343/sdutfd.1229962 |
| AMA | HASIRCI I,kotan ç EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. . 2023; 97 - 105. 10.17343/sdutfd.1229962 |
| Vancouver | HASIRCI I,kotan ç EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. . 2023; 97 - 105. 10.17343/sdutfd.1229962 |
| IEEE | HASIRCI I,kotan ç "EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM." , ss.97 - 105, 2023. 10.17343/sdutfd.1229962 |
| ISNAD | HASIRCI, ISMAIL - kotan, çetin. "EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM". (2023), 97-105. https://doi.org/10.17343/sdutfd.1229962 |
| APA | HASIRCI I, kotan ç (2023). EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, 30(1), 97 - 105. 10.17343/sdutfd.1229962 |
| Chicago | HASIRCI ISMAIL,kotan çetin EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi 30, no.1 (2023): 97 - 105. 10.17343/sdutfd.1229962 |
| MLA | HASIRCI ISMAIL,kotan çetin EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, vol.30, no.1, 2023, ss.97 - 105. 10.17343/sdutfd.1229962 |
| AMA | HASIRCI I,kotan ç EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi. 2023; 30(1): 97 - 105. 10.17343/sdutfd.1229962 |
| Vancouver | HASIRCI I,kotan ç EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM. Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi. 2023; 30(1): 97 - 105. 10.17343/sdutfd.1229962 |
| IEEE | HASIRCI I,kotan ç "EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM." Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, 30, ss.97 - 105, 2023. 10.17343/sdutfd.1229962 |
| ISNAD | HASIRCI, ISMAIL - kotan, çetin. "EFFECTS OF PREOPERATIVE FINDINGS ON POSTOPERATIVE RESULTS IN PATIENTS UNDERGOING SURGERY FOR PRIMARY HYPERPARATHYROIDISM". Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi 30/1 (2023), 97-105. https://doi.org/10.17343/sdutfd.1229962 |
