The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors
Yıl: 2022 Cilt: 2 Sayı: 1 Sayfa Aralığı: 1 - 7 Metin Dili: İngilizce DOI: 10.5505/GJU.2022.41636 İndeks Tarihi: 21-03-2023
The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors
Öz: Objective: In this study, histological, pathological and clinical characteristics that may affect multifocality rate and multifocality in renal tumors were investigated. Materials and Methods: A total of 162 patients who underwent radical nephrectomy with the diagnosis of renal tumor from our urology clinic and urology clinics in two other hospitals between May 2002 and April 2006 and whose results were available were included in the study. Kidney samples were evaluated regarding multifocality through sections made macroscopically at an interval of 3 mm. Results: Of the patients included in the study, 92 (56.8%) were male and 70 (43.2%) were female. The mean age of the patients was 59.98 years (22-87). In 11 (6.7%) of 162 patients, a multifocality focus was pathologically observed. Satellite lesions were radiologically identified in two (18.2%) of the patients with multifocality. On the other hand, satellite lesions could not be identified radiologically in nine patients (5.5%). Univariate and multivariate analyzes were performed to determine the relation between pathological, histological, and clinical characteristics and multifocality. There was no significant relation between age, gender, smoking, the location of the tumor, pathological stage, lymph node involvement, the presence of metastasis, the size of the tumor, and histology of the tumor. Univariate analysis results showed a statistically significant relation between renal capsule involvement and renal vein involvement and multifocality (p=0.015 and p=0.004, respectively); however, only renal capsule involvement was found to be associated with multifocality in multiple logistic regression analysis (p=0.008). Conclusion: In our multicentric study including 162 patients, the multifocality rate in renal tumors was 6.7% (11 patients). There was a significant relationship between capsule involvement and multifocality (p=0.015 – p=0.008). Meta analysis is required to determine the rate of multifocality in renal tumors and identify with which clinical, pathological, and histological characteristics it is associated.
Anahtar Kelime: Böbrek Tümörlerinde Multifokalitenin Klinik, Patolojik ve Histolojik Bulgularla İlişkisi
Öz: Amaç: Biz bu çalışmamızda, böbrek tümörlerinde multifokalite oranını ve multifokaliteyi etkileyebilecek histolojik, patolojik ve klinik özellikleri araştırdık. Gereçler ve Yöntemler: Mayıs 2002- Nisan 2006 tarihleri arasında üroloji kliniğimiz ve diğer iki hastanedeki üroloji kliniklerinden böbrek tümörü tanısı ile radikal nefrektomi yapılan ve bulgularına ulaşılan 162 hasta çalışmaya alındı. Böbrek spesmenleri makroskobik ve 3 mm’lik aralıklarla ince kesit yapılarak multifokalite açısından değerlendirildi. Bulgular: Çalışmaya alınan hastaların 92’si (%56,8) erkek, 70’i (%43,2) kadındı. Hastaların ortalama yaşları 59,98 (22-87) idi. 162 hastanın 11’inde (%6,7) patolojik olarak multifokalite odağı görüldü. Multifokalite belirlenen hastaların 2’sinde (%18,2) radyolojik olarak satellite lezyon saptandı. Buna karşılık 9 hastada (%5.5) radyolojik olarak satellite lezyon saptanamadı. Patolojik, histolojik ve klinik özelliklerin multifokalite ile olan ilişkisini saptamak için univariate ve multivariate analizler yapıldı. Hasta yaşı, cinsiyet, sigara kullanımı, yerleşim yeri, patolojik evre, lenf nodu tutulumu, metastaz varlığı, tm boyutu, tm histolojisi arasında anlamlı bir ilişki saptanmadı. Univariate analiz sonucu hem renal kapsül tutulumu hem de renal ven tutulumu ile multifokalite arasında istatistiki anlamlı ilişkili saptanırken (sırasıyla p=0,015 ve p=0,004), multipl logistic regression analizinde sadece renal kapsül tutulumu multifokalite ile ilişkili olarak bulundu (p=0,008). Sonuç: Multisentrik, 162 vakalık çalışmamızda böbrek tümörlerinde multifokalite sıklığını 11 hasta (%6,7) olarak saptadık. Bizim çalışmamızda kapsül tutulumu (p=0,015 – p=0,008) ile multifokalite arasında anlamlı bir ilişki bulunmuştur. Böbrek tümörlerinde multifokalite oranının ve hangi klinik, patolojik ve histolojik özelliklerle ilişkili olduğunun saptanması için meta-analize ihtiyaç vardır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ERMEÇ B, öztürk m, Eryildirim B, Ergenekon E (2022). The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. , 1 - 7. 10.5505/GJU.2022.41636 |
| Chicago | ERMEÇ BAHADIR,öztürk metin,Eryildirim Bilal,Ergenekon Erbil The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. (2022): 1 - 7. 10.5505/GJU.2022.41636 |
| MLA | ERMEÇ BAHADIR,öztürk metin,Eryildirim Bilal,Ergenekon Erbil The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. , 2022, ss.1 - 7. 10.5505/GJU.2022.41636 |
| AMA | ERMEÇ B,öztürk m,Eryildirim B,Ergenekon E The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. . 2022; 1 - 7. 10.5505/GJU.2022.41636 |
| Vancouver | ERMEÇ B,öztürk m,Eryildirim B,Ergenekon E The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. . 2022; 1 - 7. 10.5505/GJU.2022.41636 |
| IEEE | ERMEÇ B,öztürk m,Eryildirim B,Ergenekon E "The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors." , ss.1 - 7, 2022. 10.5505/GJU.2022.41636 |
| ISNAD | ERMEÇ, BAHADIR vd. "The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors". (2022), 1-7. https://doi.org/10.5505/GJU.2022.41636 |
| APA | ERMEÇ B, öztürk m, Eryildirim B, Ergenekon E (2022). The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. Grand journal of urology (Online), 2(1), 1 - 7. 10.5505/GJU.2022.41636 |
| Chicago | ERMEÇ BAHADIR,öztürk metin,Eryildirim Bilal,Ergenekon Erbil The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. Grand journal of urology (Online) 2, no.1 (2022): 1 - 7. 10.5505/GJU.2022.41636 |
| MLA | ERMEÇ BAHADIR,öztürk metin,Eryildirim Bilal,Ergenekon Erbil The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. Grand journal of urology (Online), vol.2, no.1, 2022, ss.1 - 7. 10.5505/GJU.2022.41636 |
| AMA | ERMEÇ B,öztürk m,Eryildirim B,Ergenekon E The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. Grand journal of urology (Online). 2022; 2(1): 1 - 7. 10.5505/GJU.2022.41636 |
| Vancouver | ERMEÇ B,öztürk m,Eryildirim B,Ergenekon E The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors. Grand journal of urology (Online). 2022; 2(1): 1 - 7. 10.5505/GJU.2022.41636 |
| IEEE | ERMEÇ B,öztürk m,Eryildirim B,Ergenekon E "The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors." Grand journal of urology (Online), 2, ss.1 - 7, 2022. 10.5505/GJU.2022.41636 |
| ISNAD | ERMEÇ, BAHADIR vd. "The Relation Between Multifocality and Clinical, Pathological and Histological Results in Renal Tumors". Grand journal of urology (Online) 2/1 (2022), 1-7. https://doi.org/10.5505/GJU.2022.41636 |
