Aim: The aim of our study is to determine the clinical-pathological features of conjunc- tival lesions operated in a tertiary-care hospital in the eastern region of our country over a 10-year period. Materials and Methods: Demographic data of the patients and histopathological find- ings in the conjunctival biopsy specimens that were sent to our pathology laboratory between January 2010 and July 2020 were retrospectively analyzed. Lateralization, local- ization, distribution rates and frequency of lesions in different histopathological subgroups according to age and gender were evaluated. Results: 286 conjunctival biopsy materials from 272 patients were analyzed. The age of the patients ranged from 1 to 95, and the mean age was 50.39±23.59. One hundred and sixteen (43%) of the patients were female and 156 (57%) were male. Of the lesions, 144 (50.3%) were located in the right eye, and 142 (49.7%) were located in the left eye. In our series, the most common lesion was pterygium with a rate of 33.9%, and the second most common conjunctival lesion was nevi with a rate of 19.2%. Nevi were the most common melanocytic lesion with a rate of 93.2%. Melanocytic lesions are the most common lesions in childhood and adolescence, with a significant decrease in incidence with increasing age. Degenerative lesions were seen in all age groups, they were most common over the age of 45 (n:76, %78). In the 46-65 age groups pterygium was the most common lesion among all groups with a rate of 40.2%. Among epithelial neoplastic lesions, benign lesions, premalignant lesions, and malignant lesions were detected with a rate %2.4 %16.4, and %3.5 respectively. Most of the lesions were located in the bulbar conjunctiva (87.4%). This was followed by tarsal (5.2%), caruncle/fornix (4.9%) and limbus (2.4%) locations, respectively. Conclusion: Melanocytic lesions are more common in the first two decades, and degen- erative lesions are commonly seen after the 4th decade. In advanced ages (over 65 years), premalignant and malignant lesions are seen at a very high rate. Pterygium is accom- panied by CIN with a rate of 7% and all conjunctival lesions should be directed to the pathology laboratory for histopathological examination.