Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus

Şükrü DEĞİRMENÇAY, (Atatürk Üniversitesi, Veteriner Fakültesi, Dahiliye Anabilim Dalı, Erzurum, Türkiye)
Muhammed Sertaç EROĞLU, (Atatürk Üniversitesi, Veteriner Fakültesi, Dahiliye Anabilim Dalı, Erzurum, Türkiye)
Emre EREN (Atatürk Üniversitesi, Veteriner Fakültesi, Dahiliye Anabilim Dalı, Erzurum, Türkiye)
Kocatepe Veterinary Journal
3 0
Yıl: 2023 Cilt: 16 Sayı: 1 Sayfa Aralığı: 77 - 85 Metin Dili: İngilizce DOI: 10.30607/kvj.1205080 İndeks Tarihi: 06-04-2023

Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus

Öz:
The most common enteropathogens causing diarrhea in neonatal calves are Escherichia coli (E. coli) and rotavirus. Procalcitonin (PCT) is a parameter that has recently become widely used to determine whether infectious diseases are caused by bacteria. Iron is an essential nutrient for almost all bacterial species, and serum iron levels are used as an inflammatory biomarker. Therefore, in this study, we aimed to investigate the differential diagnosis value of serum iron and procalcitonin levels in E. coli and rotavirus diarrhea. The material of the study consisted of 30 calves 1-15 days old. Three groups were formed as: E. coli (n=10), rotavirus (n=10) and control (n=10). Calves in the E. coli group had the highest PCT (P=0.005) and CRP (P=0.003) levels, as well as the lowest Fe (P=0.000) levels. As a result, it was determined that serum Fe levels could be used as an inflammatory marker and PCT levels higher than 50 pg/mL could be used in the differential diagnosis of E. coli diarrhea in calves with 100% sensitivity and 100% specificity.
Anahtar Kelime: Diarrhea Escherichia coli Iron levels Procalcitonin Rotavirus

Escherichia coli ve Rotavirus Kaynaklı İshalli Neonatal Buzağılarda Serum Prokalsitonin ve Demir Düzeylerinin Ayırıcı Tanı Değeri

Öz:
Yeni doğan buzağılarda ishale neden olan en yaygın patojenler Escherichia coli (E. coli) ve rotavirüs’tür. Prokalsitonin (PCT), son zamanlarda bulaşıcı hastalıkların etiyolojisinin bakteriyel olup olmadığını belirlemek için yaygın olarak kullanılan bir parametredir. Demir (Fe) neredeyse tüm bakteri türleri için temel bir besin olup serum Fe düzeyleri yangısal bir biyobelirteç olarak kullanılmaktadır. Bu yüzden bu çalışmada E. coli ve rotavirüs ishallerinde serum Fe ve PCT düzeylerinin ayırıcı tanı değerini araştırmayı amaçladık. Çalışmanın materyalini 1-15 günlük 30 buzağı oluşturdu. Buzağılar E. coli (n=10), rotavirüs (n=10) ve kontrol (n=10) grubu olmak üzere 3 gruba ayrıldı. En yüksek PCT (P=0.005) ve CRP (P=0.003) değerleri ve en düşük Fe (P=0.000) değerleri E. coli grubundaki buzağılarda saptandı. Sonuç olarak, serum Fe düzeylerinin inflamatuar belirteç olarak kullanılabileceği ve 50 pg/mL'den yüksek PCT düzeylerinin buzağılarda E. coli’ye bağlı ishalin ayırıcı tanısında %100 duyarlılık ve %100 özgüllük ile kullanılabileceği belirlendi.
Anahtar Kelime: Diyare Escherichia coli Demir düzeyleri Prokalsitonin Rotavirüs

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Değirmençay Ş, EROGLU M, EREN E (2023). Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. , 77 - 85. 10.30607/kvj.1205080
Chicago Değirmençay Şükrü,EROGLU Muhammed Sertac,EREN EMRE Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. (2023): 77 - 85. 10.30607/kvj.1205080
MLA Değirmençay Şükrü,EROGLU Muhammed Sertac,EREN EMRE Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. , 2023, ss.77 - 85. 10.30607/kvj.1205080
AMA Değirmençay Ş,EROGLU M,EREN E Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. . 2023; 77 - 85. 10.30607/kvj.1205080
Vancouver Değirmençay Ş,EROGLU M,EREN E Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. . 2023; 77 - 85. 10.30607/kvj.1205080
IEEE Değirmençay Ş,EROGLU M,EREN E "Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus." , ss.77 - 85, 2023. 10.30607/kvj.1205080
ISNAD Değirmençay, Şükrü vd. "Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus". (2023), 77-85. https://doi.org/10.30607/kvj.1205080
APA Değirmençay Ş, EROGLU M, EREN E (2023). Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. Kocatepe Veterinary Journal, 16(1), 77 - 85. 10.30607/kvj.1205080
Chicago Değirmençay Şükrü,EROGLU Muhammed Sertac,EREN EMRE Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. Kocatepe Veterinary Journal 16, no.1 (2023): 77 - 85. 10.30607/kvj.1205080
MLA Değirmençay Şükrü,EROGLU Muhammed Sertac,EREN EMRE Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. Kocatepe Veterinary Journal, vol.16, no.1, 2023, ss.77 - 85. 10.30607/kvj.1205080
AMA Değirmençay Ş,EROGLU M,EREN E Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. Kocatepe Veterinary Journal. 2023; 16(1): 77 - 85. 10.30607/kvj.1205080
Vancouver Değirmençay Ş,EROGLU M,EREN E Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus. Kocatepe Veterinary Journal. 2023; 16(1): 77 - 85. 10.30607/kvj.1205080
IEEE Değirmençay Ş,EROGLU M,EREN E "Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus." Kocatepe Veterinary Journal, 16, ss.77 - 85, 2023. 10.30607/kvj.1205080
ISNAD Değirmençay, Şükrü vd. "Differential Diagnostic Value of Serum Procalcitonin and Iron Levels in Diarrheic Neonatal Calves Caused by Escherichia coli and Rotavirus". Kocatepe Veterinary Journal 16/1 (2023), 77-85. https://doi.org/10.30607/kvj.1205080
Sayfa Oluşturulma Tarihi
24-04-2024 6:24

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