TY - JOUR TI - Clinical and Biochemical Effects of Smoking on Non-Surgical Periodontal Treatment in Grade III Stage C Periodontitis Patients AB - Objective: The purpose of this study was to evaluate the effect of smoking on clinical parameters and the serum and saliva levels of RANKL, OPG, and IL-34 in periodontitis stage III grade C (III-C) patients after non-surgical periodontal treatment (NSPT). Methods: A total of 60 subjects, 40 periodontitis-III-C patients (20 smokers and 20 non-smokers) and 20 non-smoker periodontally healthy individuals, were included. All clinical periodontal parameters were recorded, and unstimulated saliva and serum samples were collected from all patients at baseline, but at 1 and 3 months only from periodontitis patients (N=40). Saliva and serum levels of RANKL, OPG, and IL-34 were analyzed by ELISA. Results: At baseline only whole mouth probing depth (PD) and percent of sites with PD>5mm were higher in smokers than non-smoker periodontitis patients (p AU - Arıkan, Volkan AU - Doğan, Başak AU - Görgülü, Nimet Gül DO - 10.33808/clinexphealthsci.1128101 PY - 2023 JO - Clinical and Experimental Health Sciences VL - 13 IS - 1 SN - 2459-1459 SP - 218 EP - 227 DB - TRDizin UR - http://search/yayin/detay/1162650 ER -