TY  - JOUR
TI  - Systemic Immune Inflammation-Index and  CANLPH Score in Patients with Mitral Stenosis  Undergoing Balloon Valvuloplasty
AB  - Objective: to evaluate CANLPH score and systemic immune inflammation index (SII) in patients with symptomatic rheumatic  mitral stenosis (MS) undergoing percutaneous mitral balloon valvuloplasty (PMBV). Methods: 62 patients who underwent PMBV in our clinic between 2018 and 2021 were included retrospectively. The patients were  divided into 2 groups according to echo score. The CANLPH score was calculated from the cut-off values of C-reactive protein to  albumin ratio (CAR), neutrophil to lymphocyte ratio (NLR) and platelet to hemoglobin ratio (PHR), determined with the Youden  index and SII by the formula platelet x neutrophil/lymphocyte. P <0.05 was considered statistically significant. Results: The mean age of the patients was 44.5±10.4 years (40 female, 64.5%). The mean values of SII and CANLPH scores were  higher in the Echo score >8 group (p <0.001, both). The mean mitral gradient before and after PMBV was 12.6±5.7mm Hg and  5.0±2.4 mm Hg, and the mean valve area was 1.12±0.27 cm2 and 1.85±0.29 cm2. A statistically significant and negative correlation  was observed between the gradient decrease after the procedure and the CANLPH score and SII (r=-0.426, p=0.001 and r=-0.418,  p=0.001, respectively). In receiver operating characteristic (ROC) curve analysis, it was concluded that the ability of CANPLH score  to predict the higher Echo scores was noninferior to SII with an area under curve (AUC:0.820 (0.701-0.906) and AUC:0.786 (0.664- 0.880), z statistics 0.576 and p=0.564. Conclusion: SII and CANLPH scores are correlated with Echo score. A significant negative relationship was found with both bio markers and gradient decrease after the PMBV.
AU  - KURT, IBRAHIM HALIL
AU  - Yıldırım, Arafat
AU  - DOGDUS, Mustafa
AU  - Acele, Armağan
AU  - Ozcan Abacioglu, Ozge
AU  - DİNDAŞ, FERHAT
AU  - Yıldız Koyunsever, Nermin
AU  - Karadeniz, Mine
DO  - 10.58600/eurjther-339
PY  - 2023
JO  - European Journal of Therapeutics
VL  - 29
IS  - 1
SN  - 2564-7784
SP  - 10
EP  - 16
DB  - TRDizin
UR  - http://search/yayin/detay/1163268
ER  -