The effect of subclinical hypothyroidism on ovarian  volume in prepubertal girls

karakuş sert, tuba; kirankaya, aysegul; Yiğit, Özgül; Ekinci, Deniz; Kılınç, Suna

doi:10.14744/nci.2021.78300

The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls

Özgül YİĞİT, (Sağlık Bilimleri Üniversitesi, İstanbul Bağcılar Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, Türkiye)

Tuba KARAKUŞ SERT, (Sağlık Bilimleri Üniversitesi, İstanbul Bağcılar Eğitim ve Araştırma Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, İstanbul, Türkiye)

Deniz EKİNCİ, (Sağlık Bilimleri Üniversitesi, İstanbul Bağcılar Eğitim ve Araştırma Hastanesi, Radyoloji Bölümü, İstanbul, Türkiye)

aysegul kirankaya, (Sağlık Bilimleri Üniversitesi, İstanbul Bağcılar Eğitim ve Araştırma Hastanesi, Biyokimya Bölümü, İstanbul, Türkiye)

Suna KILINÇ (Sağlık Bilimleri Üniversitesi, İstanbul Bağcılar Eğitim ve Araştırma Hastanesi, Çocuk Endokrinolojisi Kliniği, İstanbul, Türkiye)

İstanbul Kuzey Klinikleri

2 0

Yıl: 2023 Cilt: 10 Sayı: 1 Sayfa Aralığı: 48 - 52 Metin Dili: İngilizce DOI: 10.14744/nci.2021.78300 İndeks Tarihi: 03-05-2023

The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls

Öz:

OBJECTIVE: Enlargement and cystic changes in ovaries of patients with long-standing overt hypothyroidism have been described in numerous case reports. However, there are limited data about the effect of subclinical hypothyroidism (SH) on ovarian volume. The aim of the study is to evaluate the relationship between serum thyroid stimulating hormone (TSH) level and ovarian volume in prepubertal girls with SH. METHODS: Patients who were aged between 6 and 10 years and diagnosed with SH and age-matched healthy euthyroid controls were enrolled in the study. All subjects were prepubertal. RESULTS: Thirty-five children with SH (mean age; 7.6±1.0 years) and 50 euthyroid healthy girls (mean age; 7.7±1.2 years) were enrolled in the study. TSH and LH levels and both ovarian volumes were significantly higher in SH group than controls (p<0.05). In addition, TSH was positively correlated with ovarian volumes and LH in patients with SH (p<0.05). CONCLUSION: The results of this study showed that ovarian volumes of prepubertal girls with SH were significantly greater than those with normal thyroid function. Although ovarian enlargement and cyst formation is well recognized in long-standing overt hypothyroidism, it has been shown for the 1st time in patients with SH.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Yiğit Ö, karakuş sert t, Ekinci D, kirankaya a, Kılınç S (2023). The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. , 48 - 52. 10.14744/nci.2021.78300
Chicago	Yiğit Özgül,karakuş sert tuba,Ekinci Deniz,kirankaya aysegul,Kılınç Suna The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. (2023): 48 - 52. 10.14744/nci.2021.78300
MLA	Yiğit Özgül,karakuş sert tuba,Ekinci Deniz,kirankaya aysegul,Kılınç Suna The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. , 2023, ss.48 - 52. 10.14744/nci.2021.78300
AMA	Yiğit Ö,karakuş sert t,Ekinci D,kirankaya a,Kılınç S The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. . 2023; 48 - 52. 10.14744/nci.2021.78300
Vancouver	Yiğit Ö,karakuş sert t,Ekinci D,kirankaya a,Kılınç S The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. . 2023; 48 - 52. 10.14744/nci.2021.78300
IEEE	Yiğit Ö,karakuş sert t,Ekinci D,kirankaya a,Kılınç S "The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls." , ss.48 - 52, 2023. 10.14744/nci.2021.78300
ISNAD	Yiğit, Özgül vd. "The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls". (2023), 48-52. https://doi.org/10.14744/nci.2021.78300

APA	Yiğit Ö, karakuş sert t, Ekinci D, kirankaya a, Kılınç S (2023). The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. İstanbul Kuzey Klinikleri, 10(1), 48 - 52. 10.14744/nci.2021.78300
Chicago	Yiğit Özgül,karakuş sert tuba,Ekinci Deniz,kirankaya aysegul,Kılınç Suna The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. İstanbul Kuzey Klinikleri 10, no.1 (2023): 48 - 52. 10.14744/nci.2021.78300
MLA	Yiğit Özgül,karakuş sert tuba,Ekinci Deniz,kirankaya aysegul,Kılınç Suna The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. İstanbul Kuzey Klinikleri, vol.10, no.1, 2023, ss.48 - 52. 10.14744/nci.2021.78300
AMA	Yiğit Ö,karakuş sert t,Ekinci D,kirankaya a,Kılınç S The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. İstanbul Kuzey Klinikleri. 2023; 10(1): 48 - 52. 10.14744/nci.2021.78300
Vancouver	Yiğit Ö,karakuş sert t,Ekinci D,kirankaya a,Kılınç S The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls. İstanbul Kuzey Klinikleri. 2023; 10(1): 48 - 52. 10.14744/nci.2021.78300
IEEE	Yiğit Ö,karakuş sert t,Ekinci D,kirankaya a,Kılınç S "The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls." İstanbul Kuzey Klinikleri, 10, ss.48 - 52, 2023. 10.14744/nci.2021.78300
ISNAD	Yiğit, Özgül vd. "The effect of subclinical hypothyroidism on ovarian volume in prepubertal girls". İstanbul Kuzey Klinikleri 10/1 (2023), 48-52. https://doi.org/10.14744/nci.2021.78300