TY  - JOUR
TI  - The role of childhood trauma in patients with chronic  urticaria
AB  - OBJECTIVE: Chronic urticaria (CU) is a common skin disease in which the etiology involves immunological and psychological  factors. Childhood traumas may disrupt the development of the neuro-immuno-cutaneous-endocrine system and start a com plex pathophysiological process with inflammatory abnormalities, potentially leading to the development of skin disease. In  light of this information, we believe that childhood trauma may play a role in the onset and severity of disease in CU patients.  Our study aimed to discover a potential relationship between CU and childhood traumatic experiences. METHODS: This study was conducted with 53 controls and 50 CU patients. The participants were given a questionnaire  form that included sociodemographic information, Beck Anxiety Scale, Beck Depression Scale, and Childhood Trauma Ques tionnaire (CTQ-28). RESULTS: The rates of childhood trauma were found to be 68% in the patient group, and 54.7% in the control group. The  patient group demonstrated higher scores for moderate to severe anxiety and depression. The mean emotional abuse score  was significantly higher in early onset (<35 ages) urticaria patients in comparison to late onset urticarial (≥35 ages) and  the control group. It was found that depression scores were positively correlated with all abuse sub-types, excluding sexual  abuse, and total CTQ-28 scores. Anxiety scores were positively correlated with emotional abuse, physical neglect, emotional  neglect, and total CTQ-28 scores. CONCLUSION: Childhood traumas are associated with the early onset and severity of disease in CU patients as well as the  accompanying depression and anxiety.
AU  - Altunışık, Nihal
AU  - cansel, neslihan
AU  - Türkmen, Dursun
DO  - 10.14744/nci.2021.10170
PY  - 2023
JO  - İstanbul Kuzey Klinikleri
VL  - 10
IS  - 1
SN  - 2148-4902
SP  - 79
EP  - 86
DB  - TRDizin
UR  - http://search/yayin/detay/1165490
ER  -