Yıl: 2022 Cilt: 2 Sayı: 1 Sayfa Aralığı: 20 - 24 Metin Dili: İngilizce DOI: 10.14744/eer.2021.14622 İndeks Tarihi: 03-05-2023

Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion

Öz:
Purpose: The relationship between retinal vein occlusion (RVO) and hematologic parameters has been previously demonstrated. However, there is lacking data regarding the role of C-reactive protein (CRP) to Albumin Ratio (CAR) in patients with RVO. In this study, we aimed to investigate the relationship between CAR and RVO. Methods: A total of 126 people were included in our study, including 63 patients diagnosed with central RVO (CRVO) in our hospital and 63 control patients. All clinical, demographical, and laboratory parameters were entered into a dataset and compared between the CRVO group and the controls. Results: The mean age of the patients was 54±11 years (Female: 47.6%). CRP and CAR were significantly higher in patients with CRVO compared to controls (p<0.001, p<0.001, respectively). Logistic regression analysis demonstrated that high CAR level was an independent determinant of CRVO (Odds Ratio: 3.300, 95% Confidence interval: 1.681–6.480; p=0.001). Conclusion: Higher CAR levels may be an associated predictor of CRVO.
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  • 1. Klein R, Klein BE, Moss SE, Meuer SM. The epidemiology of retinal vein occlusion: The Beaver Dam eye study. Trans Am Ophthalmol Soc 2000;98:133–41.
  • 2. Rehak J, Rehak M. Branch retinal vein occlusion: Pathogenesis, visual prognosis, and treatment modalities. Curr Eye Res 2008;33:111–31.
  • 3. Kumar DR, Hanlin E, Glurich I, Mazza JJ, Yale SH. Virchow’s contribution to the understanding of thrombosis and cellular biology. Clin Med Res 2010;8:168–72.
  • 4. Hayreh SS, Zimmerman B, McCarthy MJ, Podhajsky P. Systemic diseases associated with various types of retinal vein occlusion. Am J Ophthalmol 2001;131:61–77.
  • 5. Prisco D, Marcucci R. Retinal vein thrombosis: risk factors, pathogenesis and therapeutic approach. Pathophysiol Haemost Thromb 2002;32:308–11.
  • 6. Mahoney PR, Wong DT, Ray JG. Retinal vein occlusion and traditional risk factors for atherosclerosis. Arch Ophthalmol 2008;5:692–9.
  • 7. Şahin M, Elbey B, Şahin A, Yüksel H, Türkcü FM, Çaça İ. Neutrophil- to-lymphocyte ratio and platelet-to-lymphocyte ratio in retinal vein occlusion. Clin Exp Optom. 2019;103:490–4
  • 8. Liu M, Chan CP, Yan BP, Zhang Q, Lam YY, Li RJ, et al. Albumin levels predict survival in patients with heart failure and preserved ejection fraction. Eur J Heart Fail 2012;14:39–44.
  • 9. Menon V, Greene T, Wang X, Pereira AA, Marcovina SM, Beck GJ, et al. C-reactive protein and albumin as predictors of all cause and cardiovascular mortality in chronic kidney disease. Kidney Int 2005;68:766–72.
  • 10. Mitchell P, Smith W, Chang A. Prevalence and associations of retinal vein occlusion in Australia: The blue mountains eye study. Arch Ophthalmol 1996;114:1243–7.
  • 11. Klein R, Moss SE, Meuer SM, Klein BE. The 15-year cumulative incidence of retinal vein occlusion: The beaver dam eye study. Arch Ophthalmol 2008;126:513–8.
  • 12. O’Mahoney PR, Wong DT, Ray JG. Retinal vein occlusion and traditional risk factors for atherosclerosis. Arch Ophthalmol 2008;126:692–9.
  • 13. Bhagat N, Goldberg MF, Gascon P, Bell W, Haberman J, Zarbin MA. Central retinal vein occlusion: Review of management. Eur J Ophthalmol 1999;9:165–80.
  • 14. The eye disease case-control study group. Risk factors for central retinal vein occlusion. Arch Ophthalmol 1996;114:545–54.
  • 15. Rehak M, Rehak J, Müller M, Faude S, Faude F, Siegemund A, et al. The prevalence of activated protein C (APC) resistance and factor V Leiden is significantly higher in patients with retinal vein occlusion without general risk factors. Thromb Haemost 2008;99:925–9.
  • 16. Janssen M, den Heijer M, Cruysberg J, Wollersheim H, Bredie SJ. Retinal vein occlusion: A form of venous thrombosis or a complication of atherosclerosis? Thromb Haemost 2005;93:1021– 6.
  • 17. Bucciarelli P, Passamonti SM, Gianniello F, Artoni A, Martinelli I. Thrombophilic and cardiovascular risk factors for retinal vein occlusion. Eur J Intern Med 2017;44:44–8.
  • 18. Citirik M. Central retinal vein occlusion associated with platelet activation. Ther Adv Ophthalmol 2019;11: 2515841419864844. doi: 10.1177/2515841419864844
  • 19. Fong AC, Schatz H. Central retinal vein occlusion in young adults. Surv Ophthalmol 1993;37:393–417.
  • 20. Chen TY, Uppuluri A, Zarbin MA, Bhagat N. Risk factors for central retinal vein occlusion in young adults. Eur J Ophthalmol 2020;1120672120960333. https://doi. org/10.1177%2F1120672120960333
  • 21. Seringec Akkececi N, Yildirim Cetin G, Gogebakan H, Acipayam C. The C-reactive protein/albumin ratio and complete blood count parameters as indicators of disease activity in patients with Takayasu arteritis. Med Sci Monit 2019;25:1401–9.
  • 22. Noma H, Yasuda K, Shimura M. Cytokines and pathogenesis of central retinal vein occlusion. J Clin Med 2020;9:3457.
  • 23. Dorajoo R, Li R, Ikram MK, Liu J, Froguel P, Lee J, et al. Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? PLoS One 2013;8:e67650.
  • 24. Süleymanoğlu M, Burak C, Gümüşdağ A, Yesin M, Rencüzoğulları İ, Karabağ Y, et al. Assessment of the relation between C-reactive protein to albumin ratio and the severity and complexity of peripheral arterial disease. Vascular 2020;28:731–8.
  • 25. Karabağ Y, Çağdaş M, Rencuzogullari I, Karakoyun S, Artaç İ, İliş D, et al. Relationship between C-reactive protein/albumin ratio and coronary artery disease severity in patients with stable angina pectoris. J Clin Lab Anal 2018;32:e22457.
APA Kutlutürk I, Bulut M (2022). Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. , 20 - 24. 10.14744/eer.2021.14622
Chicago Kutlutürk Işıl,Bulut Muhammed nurullah Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. (2022): 20 - 24. 10.14744/eer.2021.14622
MLA Kutlutürk Işıl,Bulut Muhammed nurullah Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. , 2022, ss.20 - 24. 10.14744/eer.2021.14622
AMA Kutlutürk I,Bulut M Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. . 2022; 20 - 24. 10.14744/eer.2021.14622
Vancouver Kutlutürk I,Bulut M Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. . 2022; 20 - 24. 10.14744/eer.2021.14622
IEEE Kutlutürk I,Bulut M "Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion." , ss.20 - 24, 2022. 10.14744/eer.2021.14622
ISNAD Kutlutürk, Işıl - Bulut, Muhammed nurullah. "Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion". (2022), 20-24. https://doi.org/10.14744/eer.2021.14622
APA Kutlutürk I, Bulut M (2022). Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. European eye research, 2(1), 20 - 24. 10.14744/eer.2021.14622
Chicago Kutlutürk Işıl,Bulut Muhammed nurullah Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. European eye research 2, no.1 (2022): 20 - 24. 10.14744/eer.2021.14622
MLA Kutlutürk Işıl,Bulut Muhammed nurullah Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. European eye research, vol.2, no.1, 2022, ss.20 - 24. 10.14744/eer.2021.14622
AMA Kutlutürk I,Bulut M Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. European eye research. 2022; 2(1): 20 - 24. 10.14744/eer.2021.14622
Vancouver Kutlutürk I,Bulut M Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion. European eye research. 2022; 2(1): 20 - 24. 10.14744/eer.2021.14622
IEEE Kutlutürk I,Bulut M "Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion." European eye research, 2, ss.20 - 24, 2022. 10.14744/eer.2021.14622
ISNAD Kutlutürk, Işıl - Bulut, Muhammed nurullah. "Assessment of C-reactive protein to albumin ratio in patients with retinal vein occlusion". European eye research 2/1 (2022), 20-24. https://doi.org/10.14744/eer.2021.14622