As with other lesions, there may be clinical, radiological and pathological diagnostic differences in dental lesions. Cases that are thought to be malignant and/or benign clinically and radiologically may be diagnosed differently after histopathological evaluation. For this reason, histopathological evaluation is important in determining the diagnosis and treatment protocols of lesions. Sometimes, we may encounter cases with the coexistence of several lesions. A 56-year-old male patient complained of swelling in his gums. As a result of the computed tomography examination performed after the patient's examination, swelling was detected in the left mandible corpus. Biopsy was recommended primarily for odontogenic cysts and other cystic lesions. In the histopathological evaluation, granulomatous inflammation with clefts and surrounding multinuclear giant cells and adjacent dense filamentous tangles were noted. In the histopathological evaluation of this case, the diagnosis of clefts was also important, however, it may be useful to evaluate the spectrum in granulomatous inflammation tables. Also, actinomycosis has been considered for filamentous areas. Actinomyces are included in the oral flora, but it should not be forgotten that it can cause Actinomycosis by entering the mucosa for various reasons. With its filamentous appearance, it can sometimes mimic fungal infections, and in this respect, both histopathological and histochemical studies may be required Here, a case with clinically and radiologically thought to be an odontogenic cyst and histopathologically associated with cholesterol granuloma and actinomycosis is presented.