The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection
Yıl: 2022 Cilt: 30 Sayı: 4 Sayfa Aralığı: 602 - 610 Metin Dili: İngilizce DOI: 10.5606/tgkdc.dergisi.2022.22154 İndeks Tarihi: 04-05-2023
The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection
Öz: Background: The aim of this study was to evaluate the degree and size of pleural invasion in non-small cell lung cancer patients and to compare its relationship with the survival time. Methods: Between January 2008 and June 2019, a total of 164 patients (143 males, 21 females; median age: 64.65 years; range 39 to 92 years) who underwent surgical resection with a diagnosis of non-small cell lung cancer and who were found to have pleural invasion histopathologically were retrospectively analyzed. The control group consisted of 105 patients (95 males, 10 females; median age: 61.7 years; range, 32 to 82 years) who underwent surgical resection but who were not found to have pleural invasion histopathologically during the same time period. Survival time was compared between the groups. Results: Median survival was 52 months in the group with pleural invasion, while it was 70.6 months in the group without pleural invasion. In the pleural invasion group, the patients who underwent sublobar resection had shorter survival. The degree of pleural invasion (p=0.028), advanced age (p=0.022), and lymph node involvement (p=0.011) were found to be poor prognostic factors for survival. Conclusion: In non-small cell lung cancer patients, the increase in the degree and size of pleural invasion is negatively correlated with the survival time and this is thought to be associated with advanced disease stage.
Anahtar Kelime: Cerrahi rezeksiyon uygulanan küçük hücreli dışı akciğer kanserli hastalarda plevral invazyon derecesinin sağkalıma olan etkisi
Öz: Amaç: Bu çalışmada, küçük hücreli dışı akciğer kanserli hastalarda plevral invazyon derecesi ve boyutu değerlendirildi ve sağkalım süresi ile olan ilişkisi karşılaştırıldı. Çalışma planı: Ocak 2008 - Haziran 2009 tarihleri arasında küçük hücreli dışı akciğer kanseri tanısı ile cerrahi rezeksiyon uygulanan ve histopatolojik olarak plevra invazyonu tespit edilen toplam 164 hasta (143 erkek, 21 kadın; ort. yaş: 64.65 yıl; dağılım, 39-92 yıl) retrospektif olarak incelendi. Kontrol grubu aynı dönemde cerrahi rezeksiyon uygulanan ancak histopatolojik olarak plevra invazyonu tespit edilmeyen 105 hastadan (95 erkek, 10 kadın, ort. yaş: 61.7 yıl; dağılım, 32-82 yıl) oluşuyordu. Gruplar arasında sağkalım süreleri karşılaştırıldı. Bulgular: Plevra invazyonu olan grupta medyan sağkalım 52 ay iken, plevra invazyonu olmayan grupta 70.6 ay idi. Plevra invazyonlu grupta, sublober rezeksiyon uygulananların sağkalım süresi daha kısa idi. Plevral invazyon derecesi (p=0.028), ileri yaş (p=0.022) ve lenf nodu tutulumu (p=0.011) sağkalımın kötü prognostik faktörleri olarak tespit edildi. Sonuç: Küçük hücreli dışı akciğer kanserli hastalarda plevral invazyonun derece ve boyut artışı ile sağkalım süresi negatif ilişkili olup, bu durumun ileri evre hastalık ile ilişkili olduğu düşünülmektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Celik B, Sullu Y, YILMAZ V, Taslak Sengul A, bilgin buyukkarabacak y, Gurz S, PIRZIRENLI G, basoglu a (2022). The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. , 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| Chicago | Celik Burcin,Sullu Yurdanur,YILMAZ VOLKAN,Taslak Sengul Aysen,bilgin buyukkarabacak yasemin,Gurz Selcuk,PIRZIRENLI GOKHAN,basoglu ahmet The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. (2022): 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| MLA | Celik Burcin,Sullu Yurdanur,YILMAZ VOLKAN,Taslak Sengul Aysen,bilgin buyukkarabacak yasemin,Gurz Selcuk,PIRZIRENLI GOKHAN,basoglu ahmet The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. , 2022, ss.602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| AMA | Celik B,Sullu Y,YILMAZ V,Taslak Sengul A,bilgin buyukkarabacak y,Gurz S,PIRZIRENLI G,basoglu a The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. . 2022; 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| Vancouver | Celik B,Sullu Y,YILMAZ V,Taslak Sengul A,bilgin buyukkarabacak y,Gurz S,PIRZIRENLI G,basoglu a The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. . 2022; 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| IEEE | Celik B,Sullu Y,YILMAZ V,Taslak Sengul A,bilgin buyukkarabacak y,Gurz S,PIRZIRENLI G,basoglu a "The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection." , ss.602 - 610, 2022. 10.5606/tgkdc.dergisi.2022.22154 |
| ISNAD | Celik, Burcin vd. "The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection". (2022), 602-610. https://doi.org/10.5606/tgkdc.dergisi.2022.22154 |
| APA | Celik B, Sullu Y, YILMAZ V, Taslak Sengul A, bilgin buyukkarabacak y, Gurz S, PIRZIRENLI G, basoglu a (2022). The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. Türk Göğüs Kalp Damar Cerrahisi Dergisi, 30(4), 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| Chicago | Celik Burcin,Sullu Yurdanur,YILMAZ VOLKAN,Taslak Sengul Aysen,bilgin buyukkarabacak yasemin,Gurz Selcuk,PIRZIRENLI GOKHAN,basoglu ahmet The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. Türk Göğüs Kalp Damar Cerrahisi Dergisi 30, no.4 (2022): 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| MLA | Celik Burcin,Sullu Yurdanur,YILMAZ VOLKAN,Taslak Sengul Aysen,bilgin buyukkarabacak yasemin,Gurz Selcuk,PIRZIRENLI GOKHAN,basoglu ahmet The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. Türk Göğüs Kalp Damar Cerrahisi Dergisi, vol.30, no.4, 2022, ss.602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| AMA | Celik B,Sullu Y,YILMAZ V,Taslak Sengul A,bilgin buyukkarabacak y,Gurz S,PIRZIRENLI G,basoglu a The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. Türk Göğüs Kalp Damar Cerrahisi Dergisi. 2022; 30(4): 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| Vancouver | Celik B,Sullu Y,YILMAZ V,Taslak Sengul A,bilgin buyukkarabacak y,Gurz S,PIRZIRENLI G,basoglu a The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection. Türk Göğüs Kalp Damar Cerrahisi Dergisi. 2022; 30(4): 602 - 610. 10.5606/tgkdc.dergisi.2022.22154 |
| IEEE | Celik B,Sullu Y,YILMAZ V,Taslak Sengul A,bilgin buyukkarabacak y,Gurz S,PIRZIRENLI G,basoglu a "The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection." Türk Göğüs Kalp Damar Cerrahisi Dergisi, 30, ss.602 - 610, 2022. 10.5606/tgkdc.dergisi.2022.22154 |
| ISNAD | Celik, Burcin vd. "The effects of the degree of pleural invasion on survival in patients with non-small cell lung cancer undergoing surgical resection". Türk Göğüs Kalp Damar Cerrahisi Dergisi 30/4 (2022), 602-610. https://doi.org/10.5606/tgkdc.dergisi.2022.22154 |
