TY  - JOUR
TI  - The Impact of COVID-19 on Gametes and Endometrium: A Narrative Review
AB  - The Coronavirus disease 2019 (COVID-19) has been affecting our lives since December 19. Naturally, during the COVID-19 outbreak, it has become a point of interest whether severe acute respiratory syn- drome-coronavirus-2 (SARS-CoV-2) infection might affect oocyte, and sperm and influence the implan- tation during the assisted reproductive technology cycles. In the current narrative review, we aimed to scrutinize articles about SARS-CoV-2 infection and infertility concerning the safety of gametes and the endometrium. Whereas the available data suggest that SARS-CoV-2 interferes with various types of molecular pathways in the oocyte, spermatozoa, and endometrium, the lack of co-expression in an- giotensin-converting enzyme 2 and transmembrane protease serine 2 in those cell lines theoretically avoid concerns by patients and reproductive endocrinologists. However, one should consider that those observations were based on a few case series and should be confirmed with further observational stud- ies including a larger sample size with various clinic spectrums. Alternative pathways that can be utilized by the virus to invade gametes and individual differences in molecular expression are other potential lim- itations that should be considered.
AU  - Güneş, Ali Can
AU  - Karataş, Esra
AU  - Mumusoglu, Sezcan
AU  - Bozdag, Gurkan
AU  - TEMİZ, BİLAL ESAT
DO  - 10.201613/GORM.2022.1192
PY  - 2023
JO  - GORM:Gynecology Obstetrics & Reproductive Medicine
VL  - 29
IS  - 1
SN  - 1300-4751
SP  - 75
EP  - 78
DB  - TRDizin
UR  - http://search/yayin/detay/1166311
ER  -