TY  - JOUR
TI  - The Role of Autophagy in Myocardial Ischemia and Reperfusion
AB  - Autophagy is a process in which lysosome-mediated intracellular damage or aging organelles and proteins are degraded to produce amino acids, fatty acids, ATP, etc., and then reused by cells. Under normal physiological conditions, cardiomyocytes maintain low levels of autophagy. However, autophagy is activated during myocardial ischemia-reperfusion (MI/R), and autophagosomes increase significantly, indicating that autophagy plays an important role in myocardial ischemia-reperfusion injury (MI/RI). Studies have shown that autophagy has protective and detrimental effects on MI/RI and is regulated by a variety of factors. This article reviews the relationship between autophagy and MI/RI.
AU  - WU, Shiyong
AU  - Guo, Xueli
AU  - Chen, Ningheng
DO  - 10.14744/ejmo.2023.53477
PY  - 2023
JO  - Eurasian Journal of Medicine and Oncology
VL  - 7
IS  - 1
SN  - 2587-2400
SP  - 1
EP  - 9
DB  - TRDizin
UR  - http://search/yayin/detay/1166417
ER  -