Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients
Yıl: 2023 Cilt: 33 Sayı: 1 Sayfa Aralığı: 128 - 135 Metin Dili: İngilizce DOI: 10.4274/terh.galenos.2023.48039 İndeks Tarihi: 05-05-2023
Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients
Öz: Objective: Spinal anesthesia, especially in the elderly population, may cause a range of problems from hypotension, cerebral ischemia and myocardial infarcts, to acute renal failure and cardiac arrest. In our study, we researched the effect of ephedrine, ringer lactate, and colloid solutions administered prophylactically on hemodynamic parameters in geriatric patients administered spinal anesthesia. Methods: This prospective, randomized, double-blind study included 75 patients aged 65 years and older in the American Society of Anesthesiologists I-II risk group undergoing urogenital system surgery. Patients were randomly divided into 3 groups called R, C and E. Group R was administered 1000 mL ringer lactate + 2 mL 0.9% NaCl, group C were administered 500 mL hydroxyethyl starch solution, and group E were administered 1000 mL ringer lactate + 10 mg ephedrine (with 2 mL volume). All patients had 5 mL/kg/hr ringer lactate administered for maintenance. The patients’ systolic (SBP), diastolic (DBP) and mean blood pressure (MBP), heart rate (HR), and SpO2 data were recorded. The values before administering fluids were taken as control values and a 30% fall in systolic blood pressure or systolic blood pressure <90 mmHg was accepted as hypotension, and 5 mg IV ephedrine was administered. Results: In all groups, the SBP, DBP, and MBP were identified to have statistically significant increases at prepuncture (PP) and intraoperative 5th minute (I5) times. In group C, the hemodynamic changes after the increase at PP and I5 were less for SBP, DBP and MBP compared to groups R and E. In terms of HR, only group R had a statistically significant fall. One case in group R had bradycardia was identified. Conclusion: All three methods can be used safely in the geriatric population; however, we concluded that patients with colloid infusion had more stable hemodynamic parameters.
Anahtar Kelime: Geriatrik Hastalarda Uygulanan Spinal Anestezide Proflaktik Efedrin, Ringer Laktat ve Kolloid Uygulamalarının Hemodinamik Parametreler Üzerine Etkilerinin Karşılaştırılması
Öz: Amaç: Özellikle yaşlı hasta popülasyonunda uygulanan spinal anestezi; hipotansiyondan, serebral iskemi, myokard infarktüsü, akut renal yetmezlik ve kardiyak arreste kadar varabilen bir dizi problemlere sebep olabilir. Çalışmamızda geriatrik hastalarda uygulanan spinal anestezide profilaktik olarak uygulanan efedrin, ringer laktat ve kolloid solüsyonlarının hemodinamik parametreler üzerine olan etkilerini araştırmayı amaçladık. Yöntem: Bu prospekif randomize çift-kör çalışmaya ürogenital sistem cerrahisi uygulanacak, Amerikan Anestezi Derneği I-II risk grubunda bulunan 65 yaş ve üstü 75 hasta dahil edildi. Hastalar rastgele 3 gruba ayrıldı. Gruplar R, K ve E olarak isimlendirildi. Grup R’ye 1000 mL ringer laktat + 2 mL %0,9’luk NaCl, grup K’ya 500 mL HES solüsyonu, grup E’ye 1000 mL ringer laktat + (2 mL volümde) 10 mg efedrin verildi. Tüm hastaların idamesi 5 mL/kg/saat olacak şekilde ringer laktat ile sağlandı. Hastaların sistolik (SKB), diyastolik (DKB) ve ortalama kan basıncı (OKB) kalp atım hızı (KAH) ve SpO2 verileri kayıt edildi. Hastaların sıvı verilmeden önceki değeri kontrol değer olarak baz alınarak sistolik kan basıncındaki %30’luk düşme ve sistolik kan basıncının <90 mmHg olması hipotansiyon olarak kabul edilerek 5 mg i.v. efedrin ile müdahale edildi. Bulgular: Tüm gruplarda SKB, DKB ve OKB’nin ponksiyon öncesi (PÖ) ve intraoperatif 5. dk (İ5) değerlerinde istatistiksel olarak anlamlı artış tespit edildi. Grup K’da SKB, DKB ve OKB’de PÖ ve İ5 değerindeki artıştan sonraki hemodinamik değişmeler, grup R ve E’ye göre daha az oldu. KAH bakımından sadece grup R’de istatistiksel olarak anlamlı bir düşme meydana geldi. Grup R’de 1 olguda müdahale edilmesi gereken bradikardi tespit edildi. Sonuç: Yaşlı popülasyonda her üç yöntemin de güvenle kullanılabileceği fakat kolloid infüzyonu uygulanan hastalarda hemodinamik parametrelerin daha stabil seyrettiği sonucuna vardık.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | UZUN SARITAŞ P, YELKEN B (2023). Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. , 128 - 135. 10.4274/terh.galenos.2023.48039 |
| Chicago | UZUN SARITAŞ PELİN,YELKEN BIRGUL BUYUKKIDAN Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. (2023): 128 - 135. 10.4274/terh.galenos.2023.48039 |
| MLA | UZUN SARITAŞ PELİN,YELKEN BIRGUL BUYUKKIDAN Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. , 2023, ss.128 - 135. 10.4274/terh.galenos.2023.48039 |
| AMA | UZUN SARITAŞ P,YELKEN B Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. . 2023; 128 - 135. 10.4274/terh.galenos.2023.48039 |
| Vancouver | UZUN SARITAŞ P,YELKEN B Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. . 2023; 128 - 135. 10.4274/terh.galenos.2023.48039 |
| IEEE | UZUN SARITAŞ P,YELKEN B "Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients." , ss.128 - 135, 2023. 10.4274/terh.galenos.2023.48039 |
| ISNAD | UZUN SARITAŞ, PELİN - YELKEN, BIRGUL BUYUKKIDAN. "Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients". (2023), 128-135. https://doi.org/10.4274/terh.galenos.2023.48039 |
| APA | UZUN SARITAŞ P, YELKEN B (2023). Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. İzmir Tepecik Eğitim Hastanesi Dergisi, 33(1), 128 - 135. 10.4274/terh.galenos.2023.48039 |
| Chicago | UZUN SARITAŞ PELİN,YELKEN BIRGUL BUYUKKIDAN Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. İzmir Tepecik Eğitim Hastanesi Dergisi 33, no.1 (2023): 128 - 135. 10.4274/terh.galenos.2023.48039 |
| MLA | UZUN SARITAŞ PELİN,YELKEN BIRGUL BUYUKKIDAN Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. İzmir Tepecik Eğitim Hastanesi Dergisi, vol.33, no.1, 2023, ss.128 - 135. 10.4274/terh.galenos.2023.48039 |
| AMA | UZUN SARITAŞ P,YELKEN B Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. İzmir Tepecik Eğitim Hastanesi Dergisi. 2023; 33(1): 128 - 135. 10.4274/terh.galenos.2023.48039 |
| Vancouver | UZUN SARITAŞ P,YELKEN B Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients. İzmir Tepecik Eğitim Hastanesi Dergisi. 2023; 33(1): 128 - 135. 10.4274/terh.galenos.2023.48039 |
| IEEE | UZUN SARITAŞ P,YELKEN B "Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients." İzmir Tepecik Eğitim Hastanesi Dergisi, 33, ss.128 - 135, 2023. 10.4274/terh.galenos.2023.48039 |
| ISNAD | UZUN SARITAŞ, PELİN - YELKEN, BIRGUL BUYUKKIDAN. "Comparison of the Effect of Prophylactic Ephedrin, Ringer’s Lactate, and Colloid Applied During Spinal Anaesthesia on Hemodynamic Parameters in Geriatric Patients". İzmir Tepecik Eğitim Hastanesi Dergisi 33/1 (2023), 128-135. https://doi.org/10.4274/terh.galenos.2023.48039 |
