Yıl: 2022 Cilt: 2 Sayı: 2 Sayfa Aralığı: 47 - 53 Metin Dili: İngilizce DOI: 10.14744/eer.2022.17363 İndeks Tarihi: 05-05-2023

Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients

Öz:
Purpose: The objective of the study was to evaluate the refractive outcome in corrected distance visual acuity (CDVA) of adult amblyopic eyes after Wavefront Excimer Laser Correction (WELC) surgery and determine the pre-operative factors that affect the possible visual improvement. Methods: Sixty-two patients (>21 years) with refractive anisometropic, ametropic amblyopia who underwent WELC surgery between 2014 and 2021 in our clinic were enrolled. Patients with an ocular pathology causing a decrease in vision, abnormal corneal topography, abnormal slit lamp, and fundus examinations were excluded from the study. Medical records of the pre-operative and post-operative 6th month–1 year were retrospectively reviewed for CDVA values, refractive status under cycloplegia, manifest refraction values, the binocular sensory status, and the near stereoacuity measurements. The statistical analyses were held by IBM® SPSS® Statistics 19.0 (SPSS Inc., Chicago IL, USA). Results: Sixty-two eyes of 62 patients were included in the study. Correlation analysis revealed that pre-operative logMAR CDVA (r=0.495, p=0.04) and pre-operative astigmatism values (r=0.563, p=0.03) had a statistically significant correlation with increase in visual acuity. It was observed that more significant increase in CDVA was obtained in the high astigmatism (≥3D) group (p=0.045). No statistically significant correlations were detected between post-operative increase in CDVA and age (r=–0.08, p=0.78) and type of refractive error (r=–0.19, p=0.50). There was a significant improvement in near stereoacuity measurements postoperatively (p<0.05). Conclusion: Improvement in CDVA and binocular function was observed in all adult amblyopic eyes after WELC. In adult amblyopic patients, WELC surgery of refractive errors can be an alternative treatment technique.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Zhao PF, Zhou YH, Wang NL, Zhang J. Study of the wavefront aberrations in children with amblyopia. Chin Med J (Engl). 2010;123:1431-5.
  • 2. Agca A, Ozgürhan EB, Baz O, Bozkurt E, Ozkaya A, Yaşa D, et al. Laser in situ keratomileusis in adult patients with anisometropic amblyopia. Int J Ophthalmol 2013;6:362–9.
  • 3. Lengyel D, Valmaggia C. Visual improvement of an amblyopic eye in an adult patient after visual loss in the non-amblyopic eye. Klinische Monatsblatter Fur Augenheilkunde. 2006;223:462–4.
  • 4. Wilson ME. Adult amblyopia reversed by contralateral cataract formation. J Pediatr Ophthalmol Strab 1992;29:100–2.
  • 5. Vagge A, Nelson LB. Amblyopia update: New treatments. Curr Opin Ophthalmol 2016;27:380–6.
  • 6. Hess RF, Thompson B. New insights into amblyopia: Binocular therapy and noninvasive brain stimulation. J AAPOS 2013;17:89–93.
  • 7. Hoyt C. What is next in amblyopia treatment? Ophthalmology 2015;122:871–3.
  • 8. Wong AM. New concepts concerning the neural mechanisms of amblyopia and their clinical implications. Can J Ophthalmol 2012;47:399–409.
  • 9. Tsirlin I, Colpa L, Goltz HC, Wong AM. Behavioral training as new treatment for adult amblyopia: A meta-analysis and systematic review. Investig Ophthalmol Visual Sci 2015;56:4061– 75.
  • 10. Sugar A, Rapuano CJ, Culbertson WW, Huang D, Varley GA, Agapitos PJ, et al. Laser in situ keratomileusis for myopia and astigmatism: Safety and efficacy: A report by the American academy of ophthalmology. Ophthalmology 2002;109:175– 87.
  • 11. Sutton G, Lawless M, Hodge C. Laser in situ keratomileusis in 2012: A review. Clin Exp Optom 2014;97:18–29.
  • 12. Yin ZQ, Wang H, Yu T, Ren Q, Chen L. Facilitation of amblyopia management by laser in situ keratomileusis in high anisometropic hyperopic and myopic children. J AAPOS 2007;11:571–6.
  • 13. Dedhia NC, Behl S. Laser in situ keratomileusis for anisometropic amblyopia. J Refract Surg 2000;16:S264–7.
  • 14. Sakatani K, Jabbur NS, O’Brien TP. Improvement in best corrected visual acuity in amblyopic adult eyes after laser in situ keratomileusis. J Cataract Refract Surg 2004;30:2517–21.
  • 15. Sorkin N, Varssano D, Smadja D, Klein A, Mimouni M, Rosenblatt A. Visual outcomes of laser vision correction in eyes with preoperative amblyopia. J Cataract Refract Surg 2017;43:383– 8.
  • 16. Li SM, Kang MT, Wang NL, Abariga SA. Wavefront excimer laser refractive surgery for adults with refractive errors. Cochrane Database Syst Rev 2020;12:CD012687.
  • 17. Bak E, Yang HK, Hwang JM. Validity of the worth 4 dot test in patients with red-green color vision defect. Optom Vis Sci 2017;94:626–9.
  • 18. Arruabarrena C, Teus MA, Hernandez-Verdejo JL, Canones R. Visual acuity after laser in situ keratomileusis to correct high astigmatism in adults with meridional amblyopia. Am J Ophthalmol 2011;152:964–8.
  • 19. Ghanem AA, Moad AI, Nematallah EH, El-Adawy IT, Anwar GM. Laser in situ keratomileusis for treated myopic anisometropic amblyopia in children. Saudi J Ophthalmol 2010;24:3–8.
  • 20. Lin XM, Yan XH, Wang Z, Yang B, Chen QW, Su JA, et al. Longterm efficacy of excimer laser in situ keratomileusis in the management of children with high anisometropic amblyopia. Chine Med J 2009;122:813–7.
  • 21. Phillips CB, Prager TC, McClellan G, Mintz-Hittner HA. Laser in situ keratomileusis for treated anisometropic amblyopia in awake, autofixating pediatric and adolescent patients. J Cataract Refract Surg 2004;30:2522–8.
  • 22. Erdem U, Muftuoglu O. Optical factors in increased best spectacle-corrected visual acuity after LASIK. J Refract Surg 2006;22:S1056–68.
  • 23. Gonzalez-Lopez F, Alonso-Santander N, Mompean B, Bilbao- Calabuig R, Calvache JA, Beltran J. Visual outcomes in adult amblyopic eyes with moderate myopia after corneal laser surgery versus copolymer phakic intraocular lens implant. J Cataract Refract Surg 2015;41:2513–23.
  • 24. Sengpiel F. Plasticity of the visual cortex and treatment of amblyopia. Curr Biol 2014;24:R936–40.
  • 25. Pescosolido N, Stefanucci A, Buomprisco G, Fazio S. Amblyopia treatment strategies and new drug therapies. J Pediatr Ophthalmol Strabismus 2014;51:78–86.
  • 26. Bochner DN, Sapp RW, Adelson JD, Zhang S, Lee H, Djurisic M, et al. Blocking PirB up-regulates spines and functional synapses to unlock visual cortical plasticity and facilitate recovery from amblyopia. Sci Transl Med 2014;6:258ra140.
  • 27. Spiegel DP, Baldwin AS, Hess RF. The relationship between fusion, suppression, and diplopia in normal and amblyopic vision. Invest Ophthalmol Vis Sci 2016;57:5810–7.
  • 28. Sarkar S, Bharadwaj SR, Reddy JC, Vaddavalli PK. Longitudinal changes in optical quality, spatial vision, and depth vision after laser refractive surgery for myopia. Optom Vis Sci 2020;97:360–9.
  • 29. Singh D, Saxena R, Sinha R, Titiyal JS. Stereoacuity changes after laser in situ keratomileusis. Optom Vis Sci 2015;92:196– 200.
  • 30. Mravicic I, Bohac M, Lukacevic S, Jagaric K, Maja M, Patel S. The relationship between clinical measures of aniseikonia and stereoacuity before and after LASIK. J Optom 2020;13:59–68.
APA Sarıgül Sezenöz A, Asena L, Akca Bayar S, Gökgöz G, Dursun Altinors D (2022). Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. , 47 - 53. 10.14744/eer.2022.17363
Chicago Sarıgül Sezenöz Almila,Asena Leyla,Akca Bayar Sezin,Gökgöz Gülşah,Dursun Altinors Dilek Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. (2022): 47 - 53. 10.14744/eer.2022.17363
MLA Sarıgül Sezenöz Almila,Asena Leyla,Akca Bayar Sezin,Gökgöz Gülşah,Dursun Altinors Dilek Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. , 2022, ss.47 - 53. 10.14744/eer.2022.17363
AMA Sarıgül Sezenöz A,Asena L,Akca Bayar S,Gökgöz G,Dursun Altinors D Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. . 2022; 47 - 53. 10.14744/eer.2022.17363
Vancouver Sarıgül Sezenöz A,Asena L,Akca Bayar S,Gökgöz G,Dursun Altinors D Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. . 2022; 47 - 53. 10.14744/eer.2022.17363
IEEE Sarıgül Sezenöz A,Asena L,Akca Bayar S,Gökgöz G,Dursun Altinors D "Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients." , ss.47 - 53, 2022. 10.14744/eer.2022.17363
ISNAD Sarıgül Sezenöz, Almila vd. "Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients". (2022), 47-53. https://doi.org/10.14744/eer.2022.17363
APA Sarıgül Sezenöz A, Asena L, Akca Bayar S, Gökgöz G, Dursun Altinors D (2022). Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. European eye research, 2(2), 47 - 53. 10.14744/eer.2022.17363
Chicago Sarıgül Sezenöz Almila,Asena Leyla,Akca Bayar Sezin,Gökgöz Gülşah,Dursun Altinors Dilek Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. European eye research 2, no.2 (2022): 47 - 53. 10.14744/eer.2022.17363
MLA Sarıgül Sezenöz Almila,Asena Leyla,Akca Bayar Sezin,Gökgöz Gülşah,Dursun Altinors Dilek Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. European eye research, vol.2, no.2, 2022, ss.47 - 53. 10.14744/eer.2022.17363
AMA Sarıgül Sezenöz A,Asena L,Akca Bayar S,Gökgöz G,Dursun Altinors D Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. European eye research. 2022; 2(2): 47 - 53. 10.14744/eer.2022.17363
Vancouver Sarıgül Sezenöz A,Asena L,Akca Bayar S,Gökgöz G,Dursun Altinors D Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients. European eye research. 2022; 2(2): 47 - 53. 10.14744/eer.2022.17363
IEEE Sarıgül Sezenöz A,Asena L,Akca Bayar S,Gökgöz G,Dursun Altinors D "Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients." European eye research, 2, ss.47 - 53, 2022. 10.14744/eer.2022.17363
ISNAD Sarıgül Sezenöz, Almila vd. "Results of wavefront excimer laser correction of refractive errors in adult amblyopic patients". European eye research 2/2 (2022), 47-53. https://doi.org/10.14744/eer.2022.17363