Yıl: 2022 Cilt: 10 Sayı: 6 Sayfa Aralığı: 709 - 715 Metin Dili: İngilizce DOI: 10.14235/bas.galenos.2022.30602 İndeks Tarihi: 05-05-2023

Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil

Öz:
Objective: The purpose of this present study was to make a chemical analysis of the composition of essential oil obtained from sweetgum balsam and to examine its antimicrobial, anticholinesterase, α-glucosidase inhibition, and antioxidant activities. Methods: The essential oil obtained by the hydrodistillation method was analyzed by gas chromatography-mass spectrometry systems. The antimicrobial activities of the essential oil were evaluated by disc diffusion and resazurin microplate methods, the anticholinesterase effect was determined by using in vitro AChE and BChE enzymes inhibition assays, and the antioxidant effect was evaluated by ABTS and CUPRAC methods. Results: The main components of the essential oil were determined as styrene (92.6%) and α-pinene (2.2%). The essential oil showed weak antimicrobial activity against K. pneumoniae, S. epidermidis but strong antimicrobial activity against A. baumannii, C. glabrata. It showed moderate inhibitory activity to AChE and BChE enzymes, and IC50 values were calculated as 36.5 μg/mL and 69.5 μg/mL, respectively. It also showed low inhibition of α-glucosidase (IC50 value was 637.2 μg/mL) and a similar antioxidant effect in the CUPRAC and ABTS method (A0.5 value was 637.2 μg/mL and IC50 value was 632.2 μg/mL, respectively). Conclusion: Styrax Liquidus essential oil can be considered a natural antimicrobial agent due to its strong antimicrobial activity capacity against A. baumannii and C. glabrata strains.
Anahtar Kelime:

Türk Sığala Balzamı (Styrax Liquidus) Uçucu Yağının Biyolojik Aktiviteleri ve Kimyasal Bileşimi

Öz:
Amaç: Bu çalışmada, sığala balzamından elde edilen uçucu yağın bileşiminin kimyasal analizinin yapılması, antimikrobiyal, antikolinesteraz, α-glukozidaz inhibitörü ve antioksidan aktivitelerinin incelenmesi amaçlanmıştır. Yöntemler: Hidrodistilasyon yöntemiyle elde edilen uçucu yağ, gaz kromatografisi kütle spektrometresi sistemleri ile analiz edilmiştir. Uçucu yağın antimikrobiyal aktiviteleri disk difüzyon ve resazurin mikroplak yöntemleri ile; antikolinesteraz etkisi in vitro AChE ve BChE enzimleri inhibisyon testi ile; antioksidan etkisi ise ABTS ve CUPRAC yöntemleri ile değerlendirilmiştir. Bulgular: Uçucu yağın ana bileşenleri stiren (%92,6) ve α-pinen (%2,2) olarak tespit edilmiştir. Uçucu yağ, K. pneumoniae, S. epidermidis kökenlerine karşı zayıf, A. Baumannii, C. glabrata kökenlerine karşı güçlü antimikrobiyal aktivite göstermiştir. AChE ve BChE enzimlerine orta derecede inhibitör aktivite gösterip IC50 değerleri sırasıyla 36,5 μg/mL ve 69,5 μg/mL olarak hesaplanmıştır. Ayrıca düşük oranda α-glukozidaz inhibisyonu (IC50 değeri 637,2 μg/mL) ve CUPRAC ve ABTS yönteminde benzer bir antioksidan etki (sırasıyla A0,5 değeri 637,2 μg/mL ve IC50 değeri 632,2 μg/mL) göstermiştir. Sonuç: Styrax liquidus uçucu yağı, A. baumannii ve C. glabrata suşlarına karşı güçlü antimikrobiyal aktivite kapasitesi nedeniyle doğal bir antimikrobiyal ajan olarak değerlendirilebilir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Büyükkılıç Altınbaşak B, ISSA G, Zengin Kurt B, Demirci B (2022). Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. , 709 - 715. 10.14235/bas.galenos.2022.30602
Chicago Büyükkılıç Altınbaşak Betül,ISSA GHASSAN,Zengin Kurt Belma,Demirci Betül Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. (2022): 709 - 715. 10.14235/bas.galenos.2022.30602
MLA Büyükkılıç Altınbaşak Betül,ISSA GHASSAN,Zengin Kurt Belma,Demirci Betül Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. , 2022, ss.709 - 715. 10.14235/bas.galenos.2022.30602
AMA Büyükkılıç Altınbaşak B,ISSA G,Zengin Kurt B,Demirci B Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. . 2022; 709 - 715. 10.14235/bas.galenos.2022.30602
Vancouver Büyükkılıç Altınbaşak B,ISSA G,Zengin Kurt B,Demirci B Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. . 2022; 709 - 715. 10.14235/bas.galenos.2022.30602
IEEE Büyükkılıç Altınbaşak B,ISSA G,Zengin Kurt B,Demirci B "Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil." , ss.709 - 715, 2022. 10.14235/bas.galenos.2022.30602
ISNAD Büyükkılıç Altınbaşak, Betül vd. "Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil". (2022), 709-715. https://doi.org/10.14235/bas.galenos.2022.30602
APA Büyükkılıç Altınbaşak B, ISSA G, Zengin Kurt B, Demirci B (2022). Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. Bezmiâlem Science, 10(6), 709 - 715. 10.14235/bas.galenos.2022.30602
Chicago Büyükkılıç Altınbaşak Betül,ISSA GHASSAN,Zengin Kurt Belma,Demirci Betül Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. Bezmiâlem Science 10, no.6 (2022): 709 - 715. 10.14235/bas.galenos.2022.30602
MLA Büyükkılıç Altınbaşak Betül,ISSA GHASSAN,Zengin Kurt Belma,Demirci Betül Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. Bezmiâlem Science, vol.10, no.6, 2022, ss.709 - 715. 10.14235/bas.galenos.2022.30602
AMA Büyükkılıç Altınbaşak B,ISSA G,Zengin Kurt B,Demirci B Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. Bezmiâlem Science. 2022; 10(6): 709 - 715. 10.14235/bas.galenos.2022.30602
Vancouver Büyükkılıç Altınbaşak B,ISSA G,Zengin Kurt B,Demirci B Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil. Bezmiâlem Science. 2022; 10(6): 709 - 715. 10.14235/bas.galenos.2022.30602
IEEE Büyükkılıç Altınbaşak B,ISSA G,Zengin Kurt B,Demirci B "Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil." Bezmiâlem Science, 10, ss.709 - 715, 2022. 10.14235/bas.galenos.2022.30602
ISNAD Büyükkılıç Altınbaşak, Betül vd. "Biological Activities and Chemical Composition of Turkish Sweetgum Balsam (Styrax Liquidus) Essential Oil". Bezmiâlem Science 10/6 (2022), 709-715. https://doi.org/10.14235/bas.galenos.2022.30602