TY  - JOUR
TI  - Tarantula Cubensis Extract and Low-Level Laser Therapy: A Histopathological, Radiological and Serological Analysis of Bone Repair on an Experimental Bone Defect Model
AB  - In this study, it was aimed to investigate the effects of tarantula cubensis extract (TCE) and low-level laser therapy (LLLT) on cancellous and cortical bone repair. A circular unicortical bone defect was created on both the cancellous and cortical regions of the tibia of each subject. The subjects, totaling 54 mature New Zealand rabbits, were randomly allocated into three groups (n:18 each): control, LLLT (Galium-aliminum-arsenide laser at a wavelength of 780 nm and 4 J/cm 2, 5 min/day) and TCE (1 μg/kg) groups. Relative optic density (ROD) level was higher in the TCE group than the control group on day 28 as radiological (P<0.05). In both cancellous and cortical bone, inflammatory cell densities were less on the 14 and 21st day in the TCE and LLLT groups, bone tissue formation and qualities were higher 7 and 14th days in TCE and LLLT and collagen maturation were higher 28th day in the TCE group as histopathological (P<0.05). In this study, TCE accelerates bone repair as much as LLLT and more than the control group. In conclusion, that TCE is an effective, easier to apply and more economical supportive treatment in bone defects like LLLT.
AU  - ERSÖZ KANAY, Berna
AU  - ALTAN, Feray
AU  - Altan, Semih
AU  - sağsöz, hakan
AU  - Alan, Emel
AU  - ÇEVİK, REMZİ
DO  - 10.9775/kvfd.2022.28697
PY  - 2023
JO  - Kafkas Üniversitesi Veteriner Fakültesi Dergisi
VL  - 29
IS  - 2
SN  - 1300-6045
SP  - 125
EP  - 135
DB  - TRDizin
UR  - http://search/yayin/detay/1166724
ER  -