Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye

Öz:

OBJECTIVE: Hemodialysis (HD) patients are a population at high risk for exposure to the severe respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Undiagnosed mild or asymptomatic SARS-CoV-2 infection in HD patients can make these patients a potential source of infection. In our study, we aimed to evaluate the entire spectrum of SARS-CoV-2 infection with the IgM and IgG rapid antibody kit in HD patients and healthcare providers working in HD unit. METHODS: 633 HD patients and 134 health workers from all dialysis centers (three private and three public) in Eskisehir were included in the study. Blood samples obtained from participants were allowed to clot for 30 min at room temperature at 15°C using a serum separator tube. Then it was centrifuged at 1000 g at 2–8°C for 15 min. The supernatant was collected and the samples were stored at -20°C until use. Serum samples stored at the end of the study were studied with the A.B.T.™ Biotechnology COVID-19 Rapid IgG-IgM Diagnostic Test. Routine examination was measured by standard methods. All participants were evaluated by serological analysis of IgG and IgM antibodies against the SARS-CoV-2 recombinant antigen. RESULTS: Two symptomatic HD patients (0.27%) were diagnosed with SARS-CoV-2 infection by real-time reverse-transcription- polymerase-chain - reaction test and chest tomography. In 15 (2.36%) of 633 asymptomatic patients, antibody was positive against the SARS-CoV recombinant antigen (IgG in 13, both IgG and IgM in 2), while no antibodies were detected in 134 health workers. CONCLUSION: We have shown that most HD patients with SARS-CoV-2 experience the disease asymptomatically, and that antibody testing plays an important role in identifying patients with asymptomatic infection.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ozkurt S, Tezcan N, Mengüş Ç, ÖZGÜR B, ALKAN TALİ Ö, SAİDOGLU E, OZARKAN H, GÖLGELİ H, erol m, Bilgin M, yalçın a (2022). Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. , 476 - 483. 10.14744/nci.2021.62447
Chicago	Ozkurt Sultan,Tezcan Neslihan,Mengüş Çiğdem,ÖZGÜR BÜLENT,ALKAN TALİ ÖZGE,SAİDOGLU EMCET,OZARKAN HÜLYA,GÖLGELİ HANDAN,erol mehmet,Bilgin Muzaffer,yalçın ahmet uğur Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. (2022): 476 - 483. 10.14744/nci.2021.62447
MLA	Ozkurt Sultan,Tezcan Neslihan,Mengüş Çiğdem,ÖZGÜR BÜLENT,ALKAN TALİ ÖZGE,SAİDOGLU EMCET,OZARKAN HÜLYA,GÖLGELİ HANDAN,erol mehmet,Bilgin Muzaffer,yalçın ahmet uğur Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. , 2022, ss.476 - 483. 10.14744/nci.2021.62447
AMA	Ozkurt S,Tezcan N,Mengüş Ç,ÖZGÜR B,ALKAN TALİ Ö,SAİDOGLU E,OZARKAN H,GÖLGELİ H,erol m,Bilgin M,yalçın a Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. . 2022; 476 - 483. 10.14744/nci.2021.62447
Vancouver	Ozkurt S,Tezcan N,Mengüş Ç,ÖZGÜR B,ALKAN TALİ Ö,SAİDOGLU E,OZARKAN H,GÖLGELİ H,erol m,Bilgin M,yalçın a Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. . 2022; 476 - 483. 10.14744/nci.2021.62447
IEEE	Ozkurt S,Tezcan N,Mengüş Ç,ÖZGÜR B,ALKAN TALİ Ö,SAİDOGLU E,OZARKAN H,GÖLGELİ H,erol m,Bilgin M,yalçın a "Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye." , ss.476 - 483, 2022. 10.14744/nci.2021.62447
ISNAD	Ozkurt, Sultan vd. "Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye". (2022), 476-483. https://doi.org/10.14744/nci.2021.62447

APA	Ozkurt S, Tezcan N, Mengüş Ç, ÖZGÜR B, ALKAN TALİ Ö, SAİDOGLU E, OZARKAN H, GÖLGELİ H, erol m, Bilgin M, yalçın a (2022). Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. İstanbul Kuzey Klinikleri, 9(5), 476 - 483. 10.14744/nci.2021.62447
Chicago	Ozkurt Sultan,Tezcan Neslihan,Mengüş Çiğdem,ÖZGÜR BÜLENT,ALKAN TALİ ÖZGE,SAİDOGLU EMCET,OZARKAN HÜLYA,GÖLGELİ HANDAN,erol mehmet,Bilgin Muzaffer,yalçın ahmet uğur Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. İstanbul Kuzey Klinikleri 9, no.5 (2022): 476 - 483. 10.14744/nci.2021.62447
MLA	Ozkurt Sultan,Tezcan Neslihan,Mengüş Çiğdem,ÖZGÜR BÜLENT,ALKAN TALİ ÖZGE,SAİDOGLU EMCET,OZARKAN HÜLYA,GÖLGELİ HANDAN,erol mehmet,Bilgin Muzaffer,yalçın ahmet uğur Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. İstanbul Kuzey Klinikleri, vol.9, no.5, 2022, ss.476 - 483. 10.14744/nci.2021.62447
AMA	Ozkurt S,Tezcan N,Mengüş Ç,ÖZGÜR B,ALKAN TALİ Ö,SAİDOGLU E,OZARKAN H,GÖLGELİ H,erol m,Bilgin M,yalçın a Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. İstanbul Kuzey Klinikleri. 2022; 9(5): 476 - 483. 10.14744/nci.2021.62447
Vancouver	Ozkurt S,Tezcan N,Mengüş Ç,ÖZGÜR B,ALKAN TALİ Ö,SAİDOGLU E,OZARKAN H,GÖLGELİ H,erol m,Bilgin M,yalçın a Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye. İstanbul Kuzey Klinikleri. 2022; 9(5): 476 - 483. 10.14744/nci.2021.62447
IEEE	Ozkurt S,Tezcan N,Mengüş Ç,ÖZGÜR B,ALKAN TALİ Ö,SAİDOGLU E,OZARKAN H,GÖLGELİ H,erol m,Bilgin M,yalçın a "Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye." İstanbul Kuzey Klinikleri, 9, ss.476 - 483, 2022. 10.14744/nci.2021.62447
ISNAD	Ozkurt, Sultan vd. "Evaluation of hemodialysis patients and hemodialysis health workers with COVID-19 IgM and IgG antibody test; a multicenter study from Eskisehir, Turkiye". İstanbul Kuzey Klinikleri 9/5 (2022), 476-483. https://doi.org/10.14744/nci.2021.62447