Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates

TOPUZ, Mehmet

doi:10.17515/resm2022.434me0520

Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates

Mehmet TOPUZ (Makine Mühendisliği Bölümü, Van Yüzüncü Yıl Üniversitesi, Van, Türkiye)

Research on Engineering Structures and Materials

1 0

Yıl: 2022 Cilt: 8 Sayı: 4 Sayfa Aralığı: 721 - 733 Metin Dili: İngilizce DOI: 10.17515/resm2022.434me0520 İndeks Tarihi: 08-05-2023

Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates

Öz:

The study aimed to reduce the high biodegradability of magnesium (Mg) as well as local infections due to the hydrogen gas formation because of pH increasement around biological tissues. Composite coatings of poly– (lactic acid)/hydroxyapatite (PLA/HA) are commonly employed, although their adhesive strength to the metallic substrates are insufficient. In this study, PLA/HA-zirconia (ZrO2) hybrid coatings were successfully coated on Mg surfaces by means of dip-coating method to enhance this insufficient adhesion strength at the coating - Mg substrate interface with desired surface morphology. Scanning electron microscopy (SEM) micrographs were used to examine the surface morphologies of the coatings, both energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD) analyses to characterize them elementally and phase formation, respectively. Micro-Vickers hardness measurements were taken on coatings and tape tests were carried out following ASTM D3359 standard to reveal the adhesion strengths. The agglomeration size on the coating surfaces decreased as the ZrO2 reinforcement increased, and the Mg surface was entirely sealed with 30 wt% ZrO2 reinforcement, according to the SEM micrographs. The presence of both HA and ZrO2 in the coating was confirmed by XRD analysis, which also demonstrated that it was crystalline. Adhesion strengths were determined 1B, 3B, 4B, and 5B for HA, HA-10%ZrO2, HA-20%ZrO2, and HA-%30 ZrO2 reinforced hybrid coatings, respectively. As a result, it was concluded that hybrid coatings which reinforcements of ZrO2 particles to the PLA/HA composite coatings reduced agglomeration and enhance the coating - substrate adhesion at the interface.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

[1] Santos-Coquillat A, Martínez-Campos E, Mora Sánchez H, Moreno L, Arrabal R, Mohedano M, Hybrid functionalized coatings on Metallic Biomaterials for Tissue Engineering. Surface Coatings Technology, 2021; 422(July). https://doi.org/10.1016/j.surfcoat.2021.127508.
[2] Song J, Winkeljann B, Lieleg O. Biopolymer-Based Coatings: Promising Strategies to Improve the Biocompatibility and Functionality of Materials Used in Biomedical Engineering. Advanced Materials Interfaces, 2020; 7(17). https://doi.org/10.1002/admi.202000850.
[3] Topuz M, Dikici B, Gavgalı M, Yılmazer Y. Effect of hydroxyapatite:zirconia volume fraction ratio on mechanical and corrosive properties of Ti-matrix composite scaffolds. Transactions of Nonferrous Metals Society of China, 2022; 32(3): 882–894. https://doi.org/10.1016/s1003-6326(22)65840-0.
[4] Topuz M, Dikici B, Gavgali M. Titanium-based composite scaffolds reinforced with hydroxyapatite-zirconia: Production, mechanical and in-vitro characterization. Journal of the Mechanical Behavior of Biomedical Materials, June 2021; 118(March): 104480. https://doi.org/10.1016/j.jmbbm.2021.104480.
[5] Çomaklı O. Improved structural, mechanical, corrosion and tribocorrosion properties of Ti45Nb alloys by TiN, TiAlN monolayers, and TiAlN/TiN multilayer ceramic films. Ceramics International, 2021; 47(3): 4149–4156. https://doi.org/10.1016/j.ceramint.2020.09.292.
[6] Songur F, Dikici B, Niinomi M, Arslan E. The plasma electrolytic oxidation (PEO) coatings to enhance in-vitro corrosion resistance of Ti–29Nb–13Ta–4.6Zr alloys: The combined effect of duty cycle and the deposition frequency. Surface and Coatings Technology, 2019; 374(April): 345–354. https://doi.org/10.1016/j.surfcoat.2019.06.025.
[7] Niinomi M, Nakai M. Titanium-Based Biomaterials for Preventing Stress Shielding between Implant Devices and Bone. International Journal of Biomaterials, 2011;2011:1–10. https://doi.org/10.1155/2011/836587.
[8] Topuz M, Dikici B, Gavgali M, Kaseem M. Processing of Ti/(HA+ZrO2) biocomposite and 50% porous hybrid scaffolds with low Young’s modulus by powder metallurgy: Comparing of structural, mechanical, and corrosion properties. Materials Today Communications, 2021; 29(August): 102813. https://doi.org/10.1016/j.mtcomm.2021.102813.
[9] Rahman M, Li Y, Wen C. HA coating on Mg alloys for biomedical applications: A review. Journal of Magnesium and Alloys, 2020; 8(3): 929–943. https://doi.org/10.1016/j.jma.2020.05.003.
[10] Gao J, Su Y, Qin YX. Calcium phosphate coatings enhance biocompatibility and degradation resistance of magnesium alloy: Correlating in vitro and in vivo studies. Bioactive Materials, 2021; 6(5): 1223–1229. https://doi.org/10.1016/j.bioactmat.2020.10.024.
[11] Sarian MN, Iqbal N, Sotoudehbagha P, Razavi M, Ahmed QU, Sukotjo C, et al. Potential bioactive coating system for high-performance absorbable magnesium bone implants. Bioactive Materials, 2022; 12(October 2021): 42–63. https://doi.org/10.1016/j.bioactmat.2021.10.034.
[12] Li X, Weng Z, Yuan W, Luo X, Wong HM, Liu X, et al. Corrosion resistance of dicalcium phosphate dihydrate/poly(lactic-co-glycolic acid) hybrid coating on AZ31 magnesium alloy. Corrosion Science, 2016; 102: 209–221. https://doi.org/10.1016/j.corsci.2015.10.010.
[13] Shi P, Niu B, E S, Chen Y, Li Q. Preparation and characterization of PLA coating and PLA/MAO composite coatings on AZ31 magnesium alloy for improvement of corrosion resistance. Surface and Coatings Technology, 2015;262:26–32. https://doi.org/10.1016/j.surfcoat.2014.11.069.
[14] Jin J, Chen X, Zhou S. Biocorrosion evaluation and bonding strength of HA-CS/PLA hybrid coating on micro-arc oxidised AZ91D magnesium alloy. Materials Technology, 2020; 00(00): 1–8. https://doi.org/10.1080/10667857.2020.1863556.
[15] Yamada S, Yamamoto A, Kasuga T. Poly(l-lactic acid)/vaterite composite coatings on metallic magnesium. Journal of Materials Science: Materials in Medicine, 2014; 25(12): 2639–2647. https://doi.org/10.1007/s10856-014-5302-5.
[16] Li H yang, Huang D ni, Ren K feng, Ji J. Inorganic-polymer composite coatings for biomedical devices. Smart Materials in Medicine, 2021; 2(August 2020): 1–14. https://doi.org/10.1016/j.smaim.2020.10.002.
[17] Vacaras S, Baciut M, Lucaciu O, Dinu C, Baciut G, Crisan L, et al. Understanding the basis of medical use of poly-lactide-based resorbable polymers and composites–a review of the clinical and metabolic impact. Drug Metabolism Reviews, 2019; 51(4): 570–588. https://doi.org/10.1080/03602532.2019.1642911. [18] Liu S, Qin S, He M, Zhou D, Qin Q, Wang H. Current applications of poly(lactic acid) composites in tissue engineering and drug delivery. Composites Part B: Engineering, 2020; 199(May). https://doi.org/10.1016/j.compositesb.2020.108238.
[19] Zan J, Qian G, Deng F, Zhang J, Zeng Z, Peng S, et al. Dilemma and breakthrough of biodegradable poly-L-lactic acid in bone tissue repair. Journal of Materials Research and Technology, 2022; 17: 2369–2387. https://doi.org/10.1016/j.jmrt.2022.01.164.
[20] Narayanan G, Vernekar VN, Kuyinu EL, Laurencin CT. Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering. Advanced Drug Delivery Reviews, 2016; 107: 247–276. https://doi.org/10.1016/j.addr.2016.04.015.
[21] Chen Y, Geever LM, Killion JA, Lyons JG, Higginbotham CL, Devine DM. Review of Multifarious Applications of Poly (Lactic Acid). Polymer-Plastics Technology and Materials, 2016; 55(10): 1057–1075. https://doi.org/10.1080/03602559.2015.1132465. [22] Roointan A, Kianpour S, Memari F, Gandomani M, Gheibi Hayat SM, Mohammadi- Samani S. Poly(lactic-co-glycolic acid): The most ardent and flexible candidate in biomedicine! International Journal of Polymeric Materials, 2018; 67(17): 1028–1049. https://doi.org/10.1080/00914037.2017.1405350.
[23] Dikici B, Niinomi M, Topuz M, Koc SG, Nakai M. Synthesis of biphasic calcium phosphate (BCP) coatings on β‒type titanium alloys reinforced with rutile-TiO2 compounds: adhesion resistance and in-vitro corrosion. Journal of Sol-Gel Science and Technology, September 27, 2018; 87(3): 713–724. https://doi.org/10.1007/s10971- 018-4755-2.
[24] Dikici B, Niinomi M, Topuz M, Say Y, Aksakal B, Yilmazer H, et al. Synthesis and Characterization of Hydroxyapatite/TiO2 Coatings on the β-Type Titanium Alloys with Different Sintering Parameters using Sol-Gel Method. Protection of Metals and Physical Chemistry of Surfaces, May 16, 2018; 54(3): 457–462. https://doi.org/10.1134/S2070205118030255.
[25] Yigit O, Dikici B, Ozdemir N, Arslan E, Senocak TC, Ozdemir N. Plasma electrolytic oxidation of Ti-6Al-4V alloys in nHA/GNS containing electrolytes for biomedical applications: The combined effect of the deposition frequency and GNS weight percentage. Surface and Coatings Technology, July 2021; 32(March): 127139. https://doi.org/10.1007/s10856-021-06514-w.
[26] Yuan Q, Wu J, Qin C, Xu A, Zhang Z, Lin S, et al. Spin-coating synthesis and characterization of Zn-doped hydroxyapatite/polylactic acid composite coatings. Surface and Coatings Technology, 2016; 307: 461–469. https://doi.org/10.1016/j.surfcoat.2016.09.021.
[27] Pitjamit S, Thunsiri K, Nakkiew W, Wongwichai T, Pothacharoen P, Wattanutchariya W. The Possibility of Interlocking Nail Fabrication from FFF 3D Printing PLA/PCL/HA Composites Coated by Local Silk Fibroin for Canine Bone Fracture Treatment. Materials (Basel), March 28, 2020; 13(7): 1564. https://doi.org/10.3390/ma13071564.
[28] Heimann RB. Plasma-Sprayed Hydroxylapatite-Based Coatings: Chemical, Mechanical, Microstructural, and Biomedical Properties. Journal of Thermal Spray Technology, 2016; 25(5): 827–850. https://doi.org/10.1007/s11666-016-0421-9.
[29] Dikici B, Topuz M. Production of Annealed Cold-Sprayed 316L Stainless Steel Coatings for Biomedical Applications and Their in-vitro Corrosion Response. Protection of Metals and Physical Chemistry of Surfaces, March 5, 2018; 54(2): 333–339. https://doi.org/10.1134/S2070205118020168.
[30] Kong D, Long D, Wu Y, Zhou C. Mechanical properties of hydroxyapatite-zirconia coatings prepared by magnetron sputtering. Transactions of Nonferrous Metals Society of China, 2012; 22(1): 104–110. https://doi.org/10.1016/S1003-6326(11)61147-3.
[31] He DH, Wang P, Liu P, Liu XK, Ma FC, Zhao J. HA coating fabricated by electrochemical deposition on modified Ti6Al4V alloy. Surface and Coatings Technology, 2015; 277: 203–209. https://doi.org/10.1016/j.surfcoat.2015.07.038.
[32] Dikici B, Niinomi M, Topuz M, Say Y, Aksakal B, Yilmazer H, et al. Synthesis and Characterization of Hydroxyapatite/TiO2 Coatings on the β-Type Titanium Alloys with Different Sintering Parameters using Sol-Gel Method. Protection of Metals and Physical Chemistry of Surfaces, May 2018; 54(3): 457–462. https://doi.org/10.1134/S2070205118030255.
[33] Mohseni E, Zalnezhad E, Bushroa AR. Comparative investigation on the adhesion of hydroxyapatite coating on Ti-6Al-4V implant: A review paper. International Journal of Adhesion and Adhesives, 2014; 48: 238–257. https://doi.org/10.1016/j.ijadhadh.2013.09.030.
[34] Harb SV, Bassous NJ, de Souza TAC, Trentin A, Pulcinelli SH, Santilli CV, Webster TJ, Lobo AO, Hammer P. Hydroxyapatite and β-TCP modified PMMA-TiO2 and PMMA-ZrO2 coatings for bioactive corrosion protection of Ti6Al4V implants. Materials Science and Engineering: C, 2020; 116: 111149. https://doi.org/10.1016/j.msec.2020.111149.
[35] ASTM D3359-09. Standard Test Methods for Measuring Adhesion by Tape Test, 2012. https://doi.org/10.1520/D3359-09E02.2.
[36] Silina YE, Gernaey KV, Semenova D, Iatsunskyi I. Application of Organic-Inorganic Hybrids in Chemical Analysis, Bio- and Environmental Monitoring. Applied Sciences, 2020; 10(4): 1458. https://doi.org/10.3390/app10041458.
[37] Rauta PR, Manivasakan P, Rajendran V, Sahu BB, Panda BK, Mohapatra P. Phase transformation of ZrO2 nanoparticles produced from zircon. Phase Transitions, 2012; 85(1–2): 13–26. https://doi.org/10.1080/01411594.2011.619698.
[38] Topuz, M. Dikici, B. Two simple methods for surface modification of lithium disilicate dental blocks with hydroxyapatite, Research on Engineering Structures and Materials (RESM), 2019; 1: 97-104. https://doi.org/10.17515/resm2019.132me0506tn.
[39] Chen QZ, Blaker JJ, Boccaccini AR. Bioactive and Mechanically Strong Bioglass®- Poly(D,L-Lactic Acid) Composite Coatings on Surgical Sutures. Journal of Biomedical Materials Research – Part B, 2005; 76B(2): 354-363. https://doi.org/10.1002/jbm.b.30379.

APA	TOPUZ M (2022). Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. , 721 - 733. 10.17515/resm2022.434me0520
Chicago	TOPUZ Mehmet Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. (2022): 721 - 733. 10.17515/resm2022.434me0520
MLA	TOPUZ Mehmet Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. , 2022, ss.721 - 733. 10.17515/resm2022.434me0520
AMA	TOPUZ M Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. . 2022; 721 - 733. 10.17515/resm2022.434me0520
Vancouver	TOPUZ M Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. . 2022; 721 - 733. 10.17515/resm2022.434me0520
IEEE	TOPUZ M "Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates." , ss.721 - 733, 2022. 10.17515/resm2022.434me0520
ISNAD	TOPUZ, Mehmet. "Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates". (2022), 721-733. https://doi.org/10.17515/resm2022.434me0520

APA	TOPUZ M (2022). Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. Research on Engineering Structures and Materials, 8(4), 721 - 733. 10.17515/resm2022.434me0520
Chicago	TOPUZ Mehmet Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. Research on Engineering Structures and Materials 8, no.4 (2022): 721 - 733. 10.17515/resm2022.434me0520
MLA	TOPUZ Mehmet Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. Research on Engineering Structures and Materials, vol.8, no.4, 2022, ss.721 - 733. 10.17515/resm2022.434me0520
AMA	TOPUZ M Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. Research on Engineering Structures and Materials. 2022; 8(4): 721 - 733. 10.17515/resm2022.434me0520
Vancouver	TOPUZ M Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates. Research on Engineering Structures and Materials. 2022; 8(4): 721 - 733. 10.17515/resm2022.434me0520
IEEE	TOPUZ M "Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates." Research on Engineering Structures and Materials, 8, ss.721 - 733, 2022. 10.17515/resm2022.434me0520
ISNAD	TOPUZ, Mehmet. "Effect of ZrO2 on morphological and adhesion properties of hydroxyapatite reinforced poly– (lactic) acid matrix hybrid coatings on Mg substrates". Research on Engineering Structures and Materials 8/4 (2022), 721-733. https://doi.org/10.17515/resm2022.434me0520