Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?

Yıl: 2022 Cilt: 27 Sayı: 4 Sayfa Aralığı: 555 - 561 Metin Dili: İngilizce DOI: 10.5578/flora.20229604 İndeks Tarihi: 09-05-2023

Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?

Öz:
Introduction: Healthcare workers (HCWs) are one of the most vulnerable groups for COVID-19. SARS-CoV-2 PCR was offered to HCWs who had symptoms compatible with COVID-19 or who had a close contact with COVID-19 patient. A rapid antibody test was used to identify the risk of exposure of the HCWs who worked at high-risk units in our hospital during the first month of the pandemic. Herein, we aimed to evaluate the usefulness of this approach. Materials and Methods: The records of the HCWs from a university hospital who were tested by SARS-CoV-2 PCR or rapid antibody test between March 12, 2020 and April 04, 2020 were reviewed retrospectively. Demographic and clinical characteristics of HCWs were extracted from the electronic database. Wards or outpatient clinics that served COVID-19 patients were defined as high-risk units. Results: A total of 599 HCWs were tested for SARS-CoV-2 by PCR and 409 by rapid antibody test. Thirty-seven (6.2%) were found to be PCR positive. Eleven (29.7%) out of 37 HCWs were asymptomatic when they were tested. There was no statistically significant relationship between PCR positivity and occupation or working unit. A positive PCR result was detected in 24 HCWs during the first admission. Eleven out of 114 HCWs who were tested by a second PCR were found to be positive and two out of 17 HCWs who were tested by a third test were reported as PCR positive. Median interval between the first and second PCR was seven days (IQR= 8.5 days) and median interval between second and third PCR test was 4.5 days for the HCWs who were reported as positive at repeated PCR tests. Rapid antibody test was positive in one HCW who did not have a history of COVID-19. Conclusion: Approximately, one third of the SARS-CoV-2 PCR positive HCWs were asymptomatic. In case of increasing incidence of COVID-19 in the community, a regular screening policy for the HCWs regardless of their occupation and contact tracing might help to have a safe environment in hospitals. Screening policy should be based on well validated tests.
Anahtar Kelime:

Salgının İlk Günlerine Dönelim: Sağlık Çalışanlarında COVID-19’u Teşhis Etme Konusunda Ne Kadar Başarılı Olduk?

Öz:
Giriş: Sağlık çalışanları Koronavirüs Hastalığı 2019 (COVID-19) için en duyarlı gruplardan biridir. COVID-19 ile uyumlu belirtileri olan ve COVID-19 hastalarıyla yakın temas öyküsü olan sağlık çalışanlarına SARS-CoV-2 polimeraz zincir reaksiyonu (PCR) testi yapılması önerilmektedir. Hastanemizde pandeminin ilk ayında yüksek riskli birimlerde çalışan sağlık çalışanlarına SARS-CoV-2’ye maruziyet riskini değerlendirmek amacı bir hızlı antikor testi uygulanmıştır. Bu araştırma bu yaklaşımın kullanışlı olup olmadığının değerlendirilmesi için yapılmıştır. Materyal ve Metod: Ankara, Türkiye’den bir üniversite hastanesinde 12 Mart ve 04 Nisan 2020 tarihleri arasında SARS-CoV-2 PCR veya hızlı antikor testi ile test edilen sağlık çalışanlarının bilgileri geriye dönük olarak taranmıştır. Sağlık çalışanlarının demografik ve klinik özellikleri elektronik sistemden çekilmiştir. COVID-19 hastalarına hizmet veren poliklinik ve yatan hasta servisleri yüksek riskli birimler olarak sınıflandırılmıştır. Bulgular: Sağlık çalışanlarının 599’una SARS-CoV-2 PCR ve 409’una hızlı antikor testi uygulandı. Otuz yedi (%6.2) sağlık çalışanı PCR pozitif olarak bulundu. Otuz yedi sağlık çalışanından 11’i (%29.7) test edildiği sırada belirtisizdi. PCR pozitifliği ile meslek ve çalışılan birim arasında istatistiksel olarak anlamlı bir ilişki saptanmadı. Yirmi dört sağlık çalışanının ilk başvurusu sırasında PCR testi pozitif sonuçlandı. İkinci kez PCR testi yapılan 114 sağlık çalışanının 11’i, üçüncü kez PCR testi yapılan 17 sağlık çalışanının ikisi pozitif olarak bildirildi. Tekrarlayan PCR testlerinde pozitiflik bildirilen sağlık çalışanlarında birinci ve ikinci PCR testi arasındaki ortanca süre yedi gün (ÇADA= 8.5 gün), ikinci ve üçüncü PCR testi arasındaki ortanca süre 4.5 gündü. Hızlı antikor testi COVID-19 öyküsü olmayan bir sağlık çalışanında pozitif sonuçlandı. Sonuç: SARS-CoV-2 PCR pozitif sağlık çalışanlarının yaklaşık üçte biri asemptomatikti. Toplumda COVID-19 insidansının arttığı bir durumda sağlık çalışanları için mesleklerinden bağımsız olarak düzenli bir tarama politikası ve temaslı takibi hastanelerde güvenli bir ortam oluşturulmasında yardımcı olacaktır. Tarama politikası geçerliliği iyi gösterilmiş testlere dayanmalıdır.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Sertçelik A, Metan G, Telli Dizman G, Atılmış D, SAHAN C, kalaycı d, ALP A, CAKIR B, ZARAKOLU P, Unal S, Uzun O (2022). Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. , 555 - 561. 10.5578/flora.20229604
Chicago Sertçelik Ahmet,Metan Gökhan,Telli Dizman Gulcin,Atılmış Duygu,SAHAN CEYDA,kalaycı defne,ALP ALPASLAN,CAKIR BANU,ZARAKOLU PINAR,Unal Serhat,Uzun Omrum Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. (2022): 555 - 561. 10.5578/flora.20229604
MLA Sertçelik Ahmet,Metan Gökhan,Telli Dizman Gulcin,Atılmış Duygu,SAHAN CEYDA,kalaycı defne,ALP ALPASLAN,CAKIR BANU,ZARAKOLU PINAR,Unal Serhat,Uzun Omrum Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. , 2022, ss.555 - 561. 10.5578/flora.20229604
AMA Sertçelik A,Metan G,Telli Dizman G,Atılmış D,SAHAN C,kalaycı d,ALP A,CAKIR B,ZARAKOLU P,Unal S,Uzun O Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. . 2022; 555 - 561. 10.5578/flora.20229604
Vancouver Sertçelik A,Metan G,Telli Dizman G,Atılmış D,SAHAN C,kalaycı d,ALP A,CAKIR B,ZARAKOLU P,Unal S,Uzun O Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. . 2022; 555 - 561. 10.5578/flora.20229604
IEEE Sertçelik A,Metan G,Telli Dizman G,Atılmış D,SAHAN C,kalaycı d,ALP A,CAKIR B,ZARAKOLU P,Unal S,Uzun O "Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?." , ss.555 - 561, 2022. 10.5578/flora.20229604
ISNAD Sertçelik, Ahmet vd. "Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?". (2022), 555-561. https://doi.org/10.5578/flora.20229604
APA Sertçelik A, Metan G, Telli Dizman G, Atılmış D, SAHAN C, kalaycı d, ALP A, CAKIR B, ZARAKOLU P, Unal S, Uzun O (2022). Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, 27(4), 555 - 561. 10.5578/flora.20229604
Chicago Sertçelik Ahmet,Metan Gökhan,Telli Dizman Gulcin,Atılmış Duygu,SAHAN CEYDA,kalaycı defne,ALP ALPASLAN,CAKIR BANU,ZARAKOLU PINAR,Unal Serhat,Uzun Omrum Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 27, no.4 (2022): 555 - 561. 10.5578/flora.20229604
MLA Sertçelik Ahmet,Metan Gökhan,Telli Dizman Gulcin,Atılmış Duygu,SAHAN CEYDA,kalaycı defne,ALP ALPASLAN,CAKIR BANU,ZARAKOLU PINAR,Unal Serhat,Uzun Omrum Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, vol.27, no.4, 2022, ss.555 - 561. 10.5578/flora.20229604
AMA Sertçelik A,Metan G,Telli Dizman G,Atılmış D,SAHAN C,kalaycı d,ALP A,CAKIR B,ZARAKOLU P,Unal S,Uzun O Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi. 2022; 27(4): 555 - 561. 10.5578/flora.20229604
Vancouver Sertçelik A,Metan G,Telli Dizman G,Atılmış D,SAHAN C,kalaycı d,ALP A,CAKIR B,ZARAKOLU P,Unal S,Uzun O Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi. 2022; 27(4): 555 - 561. 10.5578/flora.20229604
IEEE Sertçelik A,Metan G,Telli Dizman G,Atılmış D,SAHAN C,kalaycı d,ALP A,CAKIR B,ZARAKOLU P,Unal S,Uzun O "Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?." Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, 27, ss.555 - 561, 2022. 10.5578/flora.20229604
ISNAD Sertçelik, Ahmet vd. "Back to the First Days of the Pandemic: How Well Have We Done to Diagnose COVID-19 in Healthcare Workers?". Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 27/4 (2022), 555-561. https://doi.org/10.5578/flora.20229604