TY  - JOUR
TI  - Prevention of hepatocellular carcinoma and monitoring of high-risk patients
AB  - Hepatocellular carcinoma (HCC) accounts for some 80% of primary liver tumors. According to recent data, HCC is the sixth most common type of cancer and the third leading cause of cancer-related mortality worldwide. Risk factors for HCC include the presence of the hepatitis B virus, hepatitis C virus, non-alcoholic fatty liver disease, and exposure to noxious agents, such as alcohol, or toxins, such as aflatoxin, which are considered prevent- able etiologies of HCC. Monitoring strategies are needed for patients at risk of developing HCC. There is a consensus on routine monitoring of cirrhotic patients due to definitive evidence of a significantly high rate of progression to HCC; however, the appropriate surveillance of patients with advanced fibrosis remains a topic of discussion. Nevertheless, adherence to a strict observation protocol is the cornerstone of early detection and treatment with curative options for patients with a high risk of developing HCC. This review examines prevention strategies, risk factors, and surveillance based on current guidelines.
AU  - Canbay, Ali
AU  - Kaya, Eda
AU  - MAZZOLINI, GUILLERMO
AU  - Yilmaz, Yusuf
DO  - 10.14744/hf.2021.2021.0033
PY  - 2022
JO  - Hepatology forum
VL  - 3
IS  - 1
SN  - 1307-5888
SP  - 23
EP  - 25
DB  - TRDizin
UR  - http://search/yayin/detay/1170041
ER  -