The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies

Erdemir, Mete; erdem, fuat; SİNCAN, gulden

doi:10.5152/eurasianjmed.2023.21124

The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies

Mete ERDEMİR, (İç Hastalıkları Anabilim Dalı, Üniversite Sağlık Bilimleri, Erzurum Bölge Eğitimi ve Araştırma Hastanesi, Erzurum, Türkiye)

Fuat ERDEM, (Hematoloji Anabilim Dalı, Atatürk Üniversitesi, Tıp Fakültesi, Erzurum, Türkiye)

Gülden SİNCAN (Hematoloji Anabilim Dalı, Atatürk Üniversitesi, Tıp Fakültesi, Erzurum, Türkiye)

Eurasian Journal of Medicine

2 0

Yıl: 2023 Cilt: 55 Sayı: 1 Sayfa Aralığı: 20 - 24 Metin Dili: İngilizce DOI: 10.5152/eurasianjmed.2023.21124 İndeks Tarihi: 15-05-2023

The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies

Öz:

Objective: Blood groups are associated with duodenal ulcer, diabetes mellitus, and urinary tract infection. In some studies, a relationship was detected between hematologic and solid organ malignancies and blood groups. In this study, we investigated the frequency and phenotypes of blood groups (ABO, Kell, Duffy, Rh) in patients with hematologic malignancies. Materials and Methods: One hundred sixty-one patients with hematologic malignancy (multiple myeloma, chronic lymphocytic leukemia, and chronic myelocytic leukemia) and 41 healthy people were evaluated pro- spectively. We determined phenotypes and distribution of ABO, Rh, Kell, and Duffy blood groups in all cases. Chi-square test and 1-way variance analysis were used for statistical analysis. P < .05 value was considered statistically significant. Results: In patients with multiple myeloma, the A blood group was statistically significantly more frequent than in the control group (P = .021). Rh negativity was found more frequent in patients with hematologic malignancy than the control group (P = .009). Kpa and Kpb antigen positivity were found statistically signifi- cantly less frequent in patients with hematologic malignancy (P = .013, P = .007; respectively). Fy (a−b−) and K−k+ phenotypes were higher in patients with hematologic cancer than in the control group (P = .045). Conclusion: We determined a significant relationship between hematologic malignancies and blood group systems. In our study, due to the low number of cases and few hematological malignancy types, extensive studies with more cases and more hematologic cancer types are needed.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Erdemir M, erdem f, SİNCAN g (2023). The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. , 20 - 24. 10.5152/eurasianjmed.2023.21124
Chicago	Erdemir Mete,erdem fuat,SİNCAN gulden The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. (2023): 20 - 24. 10.5152/eurasianjmed.2023.21124
MLA	Erdemir Mete,erdem fuat,SİNCAN gulden The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. , 2023, ss.20 - 24. 10.5152/eurasianjmed.2023.21124
AMA	Erdemir M,erdem f,SİNCAN g The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. . 2023; 20 - 24. 10.5152/eurasianjmed.2023.21124
Vancouver	Erdemir M,erdem f,SİNCAN g The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. . 2023; 20 - 24. 10.5152/eurasianjmed.2023.21124
IEEE	Erdemir M,erdem f,SİNCAN g "The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies." , ss.20 - 24, 2023. 10.5152/eurasianjmed.2023.21124
ISNAD	Erdemir, Mete vd. "The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies". (2023), 20-24. https://doi.org/10.5152/eurasianjmed.2023.21124

APA	Erdemir M, erdem f, SİNCAN g (2023). The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. Eurasian Journal of Medicine, 55(1), 20 - 24. 10.5152/eurasianjmed.2023.21124
Chicago	Erdemir Mete,erdem fuat,SİNCAN gulden The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. Eurasian Journal of Medicine 55, no.1 (2023): 20 - 24. 10.5152/eurasianjmed.2023.21124
MLA	Erdemir Mete,erdem fuat,SİNCAN gulden The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. Eurasian Journal of Medicine, vol.55, no.1, 2023, ss.20 - 24. 10.5152/eurasianjmed.2023.21124
AMA	Erdemir M,erdem f,SİNCAN g The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. Eurasian Journal of Medicine. 2023; 55(1): 20 - 24. 10.5152/eurasianjmed.2023.21124
Vancouver	Erdemir M,erdem f,SİNCAN g The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies. Eurasian Journal of Medicine. 2023; 55(1): 20 - 24. 10.5152/eurasianjmed.2023.21124
IEEE	Erdemir M,erdem f,SİNCAN g "The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies." Eurasian Journal of Medicine, 55, ss.20 - 24, 2023. 10.5152/eurasianjmed.2023.21124
ISNAD	Erdemir, Mete vd. "The Distribution and Phenotypes of Blood Groups in Hematologic Malignancies". Eurasian Journal of Medicine 55/1 (2023), 20-24. https://doi.org/10.5152/eurasianjmed.2023.21124