The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients
Yıl: 2022 Cilt: 70 Sayı: 4 Sayfa Aralığı: 349 - 357 Metin Dili: İngilizce DOI: 10.5578/tt.20229606 İndeks Tarihi: 16-05-2023
The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients
Öz: Introduction: It is known that there is a relationship between severe exacer- bations of chronic obstructive pulmonary disease(COPD) requiring hospitali- zation with loss of forced expiratory volume in one second (FEV1), impaired quality of life, and increased mortality. The aim of this study was to investiga- te factors [health-related quality of life with COPD Assessment Test (CAT), physical activity, FEV1, PaO2] affecting the time to first exacerbation (TTFE) after discharge in patients hospitalized with exacerbation. Materials and Methods: Seventy-five patients who were hospitalized due to COPD acute exacerbation were included in the study and were prospectively monitored. First exacerbation after discharge was recorded. During the first three days of hospitalization, patients were fitted with a pedometer on any of these days; 24-hour step counts were recorded and CAT was administered through face-to-face interviews. Data on age, sex, PaO2, FEV1, and comorbi- dities were recorded. The median value of the CAT scores of the participants were taken as the cut-off point. High scores were considered as an indicator of poor quality of life. Cox regression models were created for multivariate analyses and hazard ratios (HR) with 95% confidence interval (95% CI) provided. Results: There was a statistically significant relationship between the TTFE and CAT score (p= 0.001), FEV1 (pred %) (p= 0.02) and PaO2 (p= 0.02). No statistically significant relationship was found between TTFE and the number of steps used as an indicator of physical activity (p= 0.3). In multivariate analysis, age and sex adjusted CAT and PaO2 significantly affected the TTFE (HR= 2.06 CI 95%= 1.17-3.65 and HR= 5.50 CI 95%= 2.09-14.49, respectively) while adjusted FEV1 (pred %) was not significantly affected the TTFE (HR= 1.54 CI 95%= 0.88-2.70). Conclusion: The results of this study suggest that using CAT may be an easy-to-apply and practical tool to help identify patients with an increased risk of exacerbation. No significant correlation was found with the daily number of steps, which is an easily measurab- le indicator of physical activity.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Arkan Demiral G, SEN E (2022). The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. , 349 - 357. 10.5578/tt.20229606 |
| Chicago | Arkan Demiral Gökçen,SEN ELIF The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. (2022): 349 - 357. 10.5578/tt.20229606 |
| MLA | Arkan Demiral Gökçen,SEN ELIF The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. , 2022, ss.349 - 357. 10.5578/tt.20229606 |
| AMA | Arkan Demiral G,SEN E The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. . 2022; 349 - 357. 10.5578/tt.20229606 |
| Vancouver | Arkan Demiral G,SEN E The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. . 2022; 349 - 357. 10.5578/tt.20229606 |
| IEEE | Arkan Demiral G,SEN E "The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients." , ss.349 - 357, 2022. 10.5578/tt.20229606 |
| ISNAD | Arkan Demiral, Gökçen - SEN, ELIF. "The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients". (2022), 349-357. https://doi.org/10.5578/tt.20229606 |
| APA | Arkan Demiral G, SEN E (2022). The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. Tüberküloz ve Toraks, 70(4), 349 - 357. 10.5578/tt.20229606 |
| Chicago | Arkan Demiral Gökçen,SEN ELIF The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. Tüberküloz ve Toraks 70, no.4 (2022): 349 - 357. 10.5578/tt.20229606 |
| MLA | Arkan Demiral Gökçen,SEN ELIF The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. Tüberküloz ve Toraks, vol.70, no.4, 2022, ss.349 - 357. 10.5578/tt.20229606 |
| AMA | Arkan Demiral G,SEN E The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. Tüberküloz ve Toraks. 2022; 70(4): 349 - 357. 10.5578/tt.20229606 |
| Vancouver | Arkan Demiral G,SEN E The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients. Tüberküloz ve Toraks. 2022; 70(4): 349 - 357. 10.5578/tt.20229606 |
| IEEE | Arkan Demiral G,SEN E "The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients." Tüberküloz ve Toraks, 70, ss.349 - 357, 2022. 10.5578/tt.20229606 |
| ISNAD | Arkan Demiral, Gökçen - SEN, ELIF. "The effect of health-related quality of life and physical activity on time to first exacerbation in chronic obstructive pulmonary disease patients". Tüberküloz ve Toraks 70/4 (2022), 349-357. https://doi.org/10.5578/tt.20229606 |
