COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE

Koksal, Iftihar; Balta, Ozlen; aksoy, firdevs; aydın, nurten nur; ÜSTÜNDAĞ, Medine Gözde; Kaya, Selçuk; YILMAZ, Gürdal

doi:10.24938/kutfd.1086269

COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE

ÖZLEN BEKTAŞ, (Karadeniz Teknik Üniversitesi, Tıp Fakültesi, İç hastalıkları Anabilim Dalı, Hematoloji Bilim Dalı, Trabzon, Türkiye)

Firdevs AKSOY, (Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Kliniği Mikrobiyoloji Anabilim Dalı, Trabzon, Türkiye)

Nurten Nur AYDIN, (Erzurum Bölge Eğitim ve Araştırma Hastanesi, Enfeksiyon Hastalıkları ve Mikrobiyoloji Kliniği, Erzurum, Türkiye)

Medine Gözde ÜSTÜNDAĞ, (Kars İl Sağlık Müdürlüğü, Halk Sağlığı Hizmetleri Başkanlığı, Halk Sağlığı Daire Başkanlığı, Kars, Türkiye)

Selçuk Kaya, (Çanakkale Onsekiz Mart Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Çanakkale, Türkiye)

Gürdal YILMAZ, (Karadeniz Teknik Üniversitesi, Tıp Fakültesi, Enfeksiyon Hastalıkları ve Kliniği Mikrobiyoloji Anabilim Dalı, Trabzon, Türkiye)

İftihar KÖKSAL (Acıbadem Üniversitesi, Atakent Hastanesi, İstanbul, Türkiye)

Kırıkkale Üniversitesi Tıp Fakültesi Dergisi

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Yıl: 2023 Cilt: 25 Sayı: 1 Sayfa Aralığı: 10 - 15 Metin Dili: İngilizce DOI: 10.24938/kutfd.1086269 İndeks Tarihi: 22-05-2023

COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE

Öz:

Objective: Brucellosis is a systemic zoonosis that affects various organs or body systems and can mimic many diseases. Symptoms can range from acute febrile illness to chronic clinical manifestations with severe complications. In our study, we investigated the relationship between bacteremia and clinical and laboratory findings, and complications in patients with brucellosis. Material and Methods: Two hundred and twenty-three patients diagnosed with brucellosis between 2005 and 2020 in the department of infectious diseases and clinical microbiology of a tertiary care university hospital were included in the study. Rose Bengal test, Brucella standard tube agglutination test and culture (blood and/or bone marrow culture) were used for the diagnosis of brucellosis. The patients were divided into two groups according to their bacteremia status. Patients with positive culture were identified as bacteremia, and patients with negative culture were identified as non-bacteriemic. Results: A total of 223 patients were included in the study, of which 142 (63.7%) were male. While weight loss, fever and hematological complications were higher in bacteremia cases (p=0.001, p

Anahtar Kelime: Brucellosis bacteriemia complications

Bakteriyemik ve Bakteriyemik Olmayan Brusellozda Klinik, Laboratuvar Bulguları ve Komplikasyonların Karşılaştırılması: Tek Merkez Deneyimi

Öz:

Amaç: Bruselloz, çeşitli organları veya sistemleri etkileyen ve birçok hastalığı taklit edebilen sistemik bir zoonozdur. Semptomlar, akut ateşli hastalıktan ciddi komplikasyonları olan kronik klinik belirtilere kadar değişebilir. Çalışmamızda brusellozlu hastalarda bakteriyemi ile klinik ve laboratuvar bulguları arasındaki ilişkiyi ve komplikasyonları araştırdık. Gereç ve Yöntemler: 2005-2020 yılları arasında üçüncü basamak bir üniversite hastanesinde enfeksiyon hastalıkları ve klinik mikrobiyoloji anabilim dalında bruselloz tanısı alan 223 hasta çalışmaya dahil edildi. Bruselloz tanısı için Rose Bengal testi, Brucella standart tüp aglütinasyon testi ve kültür (kan ve/veya kemik iliği kültürü) kullanıldı. Hastalar bakteriyemi durumlarına göre iki gruba ayrıldı. Kan kültürü pozitif olan hastalar bakteriyemik, negatif kan kültürü olan hastalar bakteriyemik olmayan olarak tanımlandı. Bulgular: Çalışmaya dahil edilen 223 hastanın 142’si (%63.7) erkekti. Bakteriyemik olgularda kilo kaybı, ateş ve hematolojik komplikasyonlar (sırasıyla p=0.001, p

Anahtar Kelime: Bruselloz bakteremi komplikasyonlar

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Balta O, aksoy f, aydın n, ÜSTÜNDAĞ M, Kaya S, YILMAZ G, Koksal I (2023). COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. , 10 - 15. 10.24938/kutfd.1086269
Chicago	Balta Ozlen,aksoy firdevs,aydın nurten nur,ÜSTÜNDAĞ Medine Gözde,Kaya Selçuk,YILMAZ Gürdal,Koksal Iftihar COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. (2023): 10 - 15. 10.24938/kutfd.1086269
MLA	Balta Ozlen,aksoy firdevs,aydın nurten nur,ÜSTÜNDAĞ Medine Gözde,Kaya Selçuk,YILMAZ Gürdal,Koksal Iftihar COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. , 2023, ss.10 - 15. 10.24938/kutfd.1086269
AMA	Balta O,aksoy f,aydın n,ÜSTÜNDAĞ M,Kaya S,YILMAZ G,Koksal I COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. . 2023; 10 - 15. 10.24938/kutfd.1086269
Vancouver	Balta O,aksoy f,aydın n,ÜSTÜNDAĞ M,Kaya S,YILMAZ G,Koksal I COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. . 2023; 10 - 15. 10.24938/kutfd.1086269
IEEE	Balta O,aksoy f,aydın n,ÜSTÜNDAĞ M,Kaya S,YILMAZ G,Koksal I "COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE." , ss.10 - 15, 2023. 10.24938/kutfd.1086269
ISNAD	Balta, Ozlen vd. "COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE". (2023), 10-15. https://doi.org/10.24938/kutfd.1086269

APA	Balta O, aksoy f, aydın n, ÜSTÜNDAĞ M, Kaya S, YILMAZ G, Koksal I (2023). COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, 25(1), 10 - 15. 10.24938/kutfd.1086269
Chicago	Balta Ozlen,aksoy firdevs,aydın nurten nur,ÜSTÜNDAĞ Medine Gözde,Kaya Selçuk,YILMAZ Gürdal,Koksal Iftihar COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 25, no.1 (2023): 10 - 15. 10.24938/kutfd.1086269
MLA	Balta Ozlen,aksoy firdevs,aydın nurten nur,ÜSTÜNDAĞ Medine Gözde,Kaya Selçuk,YILMAZ Gürdal,Koksal Iftihar COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, vol.25, no.1, 2023, ss.10 - 15. 10.24938/kutfd.1086269
AMA	Balta O,aksoy f,aydın n,ÜSTÜNDAĞ M,Kaya S,YILMAZ G,Koksal I COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi. 2023; 25(1): 10 - 15. 10.24938/kutfd.1086269
Vancouver	Balta O,aksoy f,aydın n,ÜSTÜNDAĞ M,Kaya S,YILMAZ G,Koksal I COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi. 2023; 25(1): 10 - 15. 10.24938/kutfd.1086269
IEEE	Balta O,aksoy f,aydın n,ÜSTÜNDAĞ M,Kaya S,YILMAZ G,Koksal I "COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE." Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, 25, ss.10 - 15, 2023. 10.24938/kutfd.1086269
ISNAD	Balta, Ozlen vd. "COMPARISON OF CLINICAL, LABORATORY FINDINGS AND COMPLICATIONS IN BACTERIEMIC AND NONBACTERIEMIC BRUCELLOSIS: A SINGLE CENTER EXPERIENCE". Kırıkkale Üniversitesi Tıp Fakültesi Dergisi 25/1 (2023), 10-15. https://doi.org/10.24938/kutfd.1086269