TY  - JOUR
TI  - Restless leg syndrome and sleep quality in granulomatosis with polyangiitis
AB  - Objective: We investigated the frequency and severity of restless leg syndrome (RLS) and sleep quality in granulomatosis with polyangiitis (GPA) patients. Methods: A cross-sectional study was conducted on GPA patients. A control group was formed from patients of similar age and gender. Demographic, clinic and laboratory data were recorded. In the GPA group, disease activity was evaluated with Birmingham Vasculitis Activity score for Wegener Granulomatosis, disease-related damage by vasculitis damage index (VDI), quality of life (QoL) was by health assessment questionnaire (HAQ). In both groups, RLS diagnosis was confirmed and severity was measured according to the International Restless Legs Study Group criteria. Sleep quality was evaluated by the Pittsburgh Sleep Quality index (PSQI), sleepiness the Epworth Sleepiness scale, level of depression by the Beck Depression index (BDI). Results: Out of total 55 GPA patients, 36 who could be reached and who agreed to participate and meet the inclusion criteria were enrolled. The control group comprised 35 subjects. Age and sex were similar between groups. The frequency of RLS was similar between groups (19.4% vs. 17.1%, p=0.802). RLS severity score was indifferent. PSQI and BDI scores were increased in GPA. When parameters in GPA patients with and without RLS were compared, no significant differences were observed except for the cardiovascular damage domain of VDI. RLS severity scores did not correlate with other parameters. PSQI scores had significantly correlated with HAQ and BDI. Conclusion: The frequency of RLS was not increased in GPA compared with controls. Sleep quality was impaired and was observed to be related to worse QoL and higher scores for depression.
AU  - Güven, Serdar Can
AU  - Akyüz Dağlı, Pınar
AU  - Armagan, Berkan
AU  - erden, abdulsamet
AU  - kucuksahin, orhan
AU  - KARACAOGLU, Selin
AU  - Omma, Ahmet
DO  - 10.4274/raed.galenos.2022.36035
PY  - 2022
JO  - Ulusal Romatoloji Dergisi
VL  - 14
IS  - 3
SN  - 2651-2653
SP  - 124
EP  - 130
DB  - TRDizin
UR  - http://search/yayin/detay/1172932
ER  -