Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement
Yıl: 2022 Cilt: 47 Sayı: 6 Sayfa Aralığı: 727 - 734 Metin Dili: İngilizce DOI: 10.1515/tjb-2021-0166 İndeks Tarihi: 22-05-2023
Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement
Öz: Objectives: The variability between methods is seen in the existence of hemoglobin (Hb), triglyceride (TG), blood urea nitrogen (BUN) and glucose in the specimens, which can affect the measurement. Therefore, this study aimed to compare boronate affinity chromatography and turbidimetric inhibition immunoassay methods for glycosylated hemoglobin (HbA1c) levels in samples containing different levels of Hb, TG, BUN and glucose. Methods: In this study, a total of 412 consecutive samples were used for method comparison. The samples were divided into groups according to HbA1c, TG, BUN, Hb, and glucose levels. Clinically significant changes for HbA1c are defined as ≥0.5%. Results: Themean relative difference as%was determined as 1.4% by the Bland–Altman plot of Trinity against Roche. The Passing–Bablok analysis indicated good agreement (r=0.985) between twomethods.When compared the group with and without a clinically significant difference, we found differences only between glucose levels (p=0.003). Conclusions: High glucose levels may cause a difference between themethods. Therefore, wesuggest that amethod’s performance and properties should be considered prior to clinical usage.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | MUHTAROĞLU S, Barlak Keti D, Saracoglu H (2022). Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. , 727 - 734. 10.1515/tjb-2021-0166 |
| Chicago | MUHTAROĞLU Sabahattin,Barlak Keti Didem,Saracoglu Hatice Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. (2022): 727 - 734. 10.1515/tjb-2021-0166 |
| MLA | MUHTAROĞLU Sabahattin,Barlak Keti Didem,Saracoglu Hatice Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. , 2022, ss.727 - 734. 10.1515/tjb-2021-0166 |
| AMA | MUHTAROĞLU S,Barlak Keti D,Saracoglu H Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. . 2022; 727 - 734. 10.1515/tjb-2021-0166 |
| Vancouver | MUHTAROĞLU S,Barlak Keti D,Saracoglu H Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. . 2022; 727 - 734. 10.1515/tjb-2021-0166 |
| IEEE | MUHTAROĞLU S,Barlak Keti D,Saracoglu H "Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement." , ss.727 - 734, 2022. 10.1515/tjb-2021-0166 |
| ISNAD | MUHTAROĞLU, Sabahattin vd. "Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement". (2022), 727-734. https://doi.org/10.1515/tjb-2021-0166 |
| APA | MUHTAROĞLU S, Barlak Keti D, Saracoglu H (2022). Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. Türk Biyokimya Dergisi, 47(6), 727 - 734. 10.1515/tjb-2021-0166 |
| Chicago | MUHTAROĞLU Sabahattin,Barlak Keti Didem,Saracoglu Hatice Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. Türk Biyokimya Dergisi 47, no.6 (2022): 727 - 734. 10.1515/tjb-2021-0166 |
| MLA | MUHTAROĞLU Sabahattin,Barlak Keti Didem,Saracoglu Hatice Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. Türk Biyokimya Dergisi, vol.47, no.6, 2022, ss.727 - 734. 10.1515/tjb-2021-0166 |
| AMA | MUHTAROĞLU S,Barlak Keti D,Saracoglu H Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. Türk Biyokimya Dergisi. 2022; 47(6): 727 - 734. 10.1515/tjb-2021-0166 |
| Vancouver | MUHTAROĞLU S,Barlak Keti D,Saracoglu H Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement. Türk Biyokimya Dergisi. 2022; 47(6): 727 - 734. 10.1515/tjb-2021-0166 |
| IEEE | MUHTAROĞLU S,Barlak Keti D,Saracoglu H "Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement." Türk Biyokimya Dergisi, 47, ss.727 - 734, 2022. 10.1515/tjb-2021-0166 |
| ISNAD | MUHTAROĞLU, Sabahattin vd. "Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement". Türk Biyokimya Dergisi 47/6 (2022), 727-734. https://doi.org/10.1515/tjb-2021-0166 |
