The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth

Barlak Keti, Didem; Pamukcu, Ozge; Narin, Nazmi; Sunkak, Suleyman; Vural, Çağdaş; Baykan, Ali; Tasci, Onur; Hatipoglu, Nihal

doi:10.14744/etd.2022.41848

The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth

Onur TAŞCI, (Erciyes Üniversitesi, Tıp Fakültesi, Pediatri ve Kardiyoloji Bölümü, Kayseri, Türkiye)

Özge PAMUKÇU, (Erciyes Üniversitesi, Tıp Fakültesi, Pediatri ve Kardiyoloji Bölümü, Kayseri, Türkiye)

Nazmi NARİN, (Erciyes Üniversitesi, Tıp Fakültesi, Pediatri ve Kardiyoloji Bölümü, Kayseri, Türkiye)

Didem BARLAK KETİ, (Erciyes Üniversitesi, Tıp Fakültesi, Biyokimya Bölümü, Kayseri, Türkiye)

Süleyman SUNKAK, (Erciyes Üniversitesi, Tıp Fakültesi, Pediatri ve Kardiyoloji Bölümü, Kayseri, Türkiye)

Çağdaş VURAL, (Erciyes Üniversitesi, Tıp Fakültesi, Pediatri ve Kardiyoloji Bölümü, Kayseri, Türkiye)

Nihal HATİPOĞLU, (Erciyes Üniversitesi, Tıp Fakültesi, Pediatri Endokrinoloji Bölümü, Kayseri, Türkiye)

Ali BAYKAN (Erciyes Üniversitesi, Tıp Fakültesi, Pediatri ve Kardiyoloji Bölümü, Kayseri, Türkiye)

Erciyes Medical Journal

2 0

Yıl: 2023 Cilt: 45 Sayı: 2 Sayfa Aralığı: 145 - 151 Metin Dili: İngilizce DOI: 10.14744/etd.2022.41848 İndeks Tarihi: 23-05-2023

The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth

Öz:

Objective: Children with congenital heart disease are at risk for malnutrition. The aim of this study is to investigate the changes in appetite, nutritional hormones, and anthropometric measurements of patients before and after the transcatheter closure of ventricular septal defect. Materials and Methods: Twenty patients whose defect was closed percutaneously and 26 children as healthy control group were included in the study. The anthropometric evaluation, symptoms, and blood tests of patient group were enrolled at initial and follow-up (1st and 6th month visit). Results: The median age of patient and control group was 27 and 29.5 months, respectively. Lack of appetite, inadequate weight gain, and fatigue were higher in the patient group at initial visit (p=0.027, p=0.029, and p=0.033, respectively). At 1st month after closure, the rate of decrease in lack of appetite, inadequate weight gain, and fatigue were statistically significant (p=0.016, p=0.031, and p=0.031, respectively). After closure, increasing body mass index, its z score, and mid-upper arm circumference were statistically significant at 1st month (p=0.008, p=0.018, and p=0.018, respectively). Insulin-like growth factor-1, insulin-like growth factor binding protein-3, and their z scores were increased compared to the initial values at 1st month (p=0.001, p=0.033, p=0.002, and p=0.048, respectively). Ghrelin levels showed a linear decrease; leptin levels showed a linear increase for 6 months. Conclusion: Children with ventricular septal defect are under the risk of malnutrition. One of the goals of our treatment plan for these children should be the prevention of malnutrition; therefore, the timing of interventional therapy should be before malnutrition develops

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Tasci O, Pamukcu O, Narin N, Barlak Keti D, Sunkak S, Vural Ç, Hatipoglu N, Baykan A (2023). The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. , 145 - 151. 10.14744/etd.2022.41848
Chicago	Tasci Onur,Pamukcu Ozge,Narin Nazmi,Barlak Keti Didem,Sunkak Suleyman,Vural Çağdaş,Hatipoglu Nihal,Baykan Ali The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. (2023): 145 - 151. 10.14744/etd.2022.41848
MLA	Tasci Onur,Pamukcu Ozge,Narin Nazmi,Barlak Keti Didem,Sunkak Suleyman,Vural Çağdaş,Hatipoglu Nihal,Baykan Ali The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. , 2023, ss.145 - 151. 10.14744/etd.2022.41848
AMA	Tasci O,Pamukcu O,Narin N,Barlak Keti D,Sunkak S,Vural Ç,Hatipoglu N,Baykan A The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. . 2023; 145 - 151. 10.14744/etd.2022.41848
Vancouver	Tasci O,Pamukcu O,Narin N,Barlak Keti D,Sunkak S,Vural Ç,Hatipoglu N,Baykan A The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. . 2023; 145 - 151. 10.14744/etd.2022.41848
IEEE	Tasci O,Pamukcu O,Narin N,Barlak Keti D,Sunkak S,Vural Ç,Hatipoglu N,Baykan A "The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth." , ss.145 - 151, 2023. 10.14744/etd.2022.41848
ISNAD	Tasci, Onur vd. "The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth". (2023), 145-151. https://doi.org/10.14744/etd.2022.41848

APA	Tasci O, Pamukcu O, Narin N, Barlak Keti D, Sunkak S, Vural Ç, Hatipoglu N, Baykan A (2023). The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. Erciyes Medical Journal, 45(2), 145 - 151. 10.14744/etd.2022.41848
Chicago	Tasci Onur,Pamukcu Ozge,Narin Nazmi,Barlak Keti Didem,Sunkak Suleyman,Vural Çağdaş,Hatipoglu Nihal,Baykan Ali The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. Erciyes Medical Journal 45, no.2 (2023): 145 - 151. 10.14744/etd.2022.41848
MLA	Tasci Onur,Pamukcu Ozge,Narin Nazmi,Barlak Keti Didem,Sunkak Suleyman,Vural Çağdaş,Hatipoglu Nihal,Baykan Ali The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. Erciyes Medical Journal, vol.45, no.2, 2023, ss.145 - 151. 10.14744/etd.2022.41848
AMA	Tasci O,Pamukcu O,Narin N,Barlak Keti D,Sunkak S,Vural Ç,Hatipoglu N,Baykan A The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. Erciyes Medical Journal. 2023; 45(2): 145 - 151. 10.14744/etd.2022.41848
Vancouver	Tasci O,Pamukcu O,Narin N,Barlak Keti D,Sunkak S,Vural Ç,Hatipoglu N,Baykan A The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth. Erciyes Medical Journal. 2023; 45(2): 145 - 151. 10.14744/etd.2022.41848
IEEE	Tasci O,Pamukcu O,Narin N,Barlak Keti D,Sunkak S,Vural Ç,Hatipoglu N,Baykan A "The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth." Erciyes Medical Journal, 45, ss.145 - 151, 2023. 10.14744/etd.2022.41848
ISNAD	Tasci, Onur vd. "The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite, Hormones, and Growth". Erciyes Medical Journal 45/2 (2023), 145-151. https://doi.org/10.14744/etd.2022.41848