Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience

KAYIS, Seyit Ali; Tunç Karabekiroğlu, Nur; ERDOĞAN DÜZCÜ, SELMA; astarcı, hesna müzeyyen

doi:10.14744/etd.2023.57267

Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience

Selma ERDOĞAN DÜZCÜ, (Bolu Abant İzzet Baysal Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Bolu, Türkiye)

Nur TUNÇ KARABEKİROĞLU, (Bolu Abant İzzet Baysal Üniversitesi, Tıp Fakültesi, Patoloji Anabilim Dalı, Bolu, Türkiye)

Hesna Müzeyyen ASTARCI, (Lokman Hekim Üniversitesi, Tıp Fakültesi, Patoloji Bölümü, Ankara, Türkiye)

Seyit Ali KAYIŞ (Bolu Abant İzzet Baysal Üniversitesi, Tıp Fakültesi, Biyoistatistik Bölümü ve Tıp Bilişimi, Bolu, Türkiye)

Erciyes Medical Journal

0 0

Yıl: 2023 Cilt: 45 Sayı: 2 Sayfa Aralığı: 182 - 189 Metin Dili: İngilizce DOI: 10.14744/etd.2023.57267 İndeks Tarihi: 23-05-2023

Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience

Öz:

Objective: Thyroid fine-needle aspiration cytology is a dependable, effective method of detecting thyroid nodules. This study aims to assess the diagnostic distribution of thyroid fine-needle aspiration cytology, compare it to postoperative histological tissue diagnoses, and explore its diagnostic compatibility with published data. Materials and Methods: This single-center retrospective descriptive study included 172 cases diagnosed histopathologically out of the 1675 thyroid fine-needle aspiration cytology procedures performed in the Bolu Abant İzzet Baysal University Faculty of Medicine, Department of Medical Pathology, between 2014 and 2020. The study examined the correlation between cytological and histopathological diagnoses. Results: Of the 172 cases, 132 were female (76.74%), and 40 were male (23.26%). The participants ranged in age from 14 to 79, with a mean age of 49.23±11.83. Fine-needle aspiration cytology results were compared to tissue diagnoses. The method’s sensitivity was 61.29%, its specificity was 96.00%, its negative predictive value was 80.00%, its positive predictive value was 90.48%, and its diagnostic efficiency was 82.72%. Conclusion: In our study, the sensitivity and specificity values of cytology were high. Fine-needle aspiration cytology had limited diagnostic contributions in diagnosing papillary microcarcinoma and follicular lesions. In addition to increasing cytopathology experience to improve diagnostic compliance, we believe evaluating patients with clinical and radiological findings will better benefit patient treatment.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Erkinuresin T, Demirci H. Diagnostic accuracy of fine needle aspiration cytology of thyroid nodules. Diagnosis 2020; 7(1): 61–6.
2. Yener N, Günaldı A, Karatas HK, Yetis Mermi EU, Mokhtare S, Özer E, et al. A single institutional Experience with fine needle aspiration biopsy of thyroid nodules: correlation of the cytologic, histopathologic and ultrasonographic findings of 284 cases. Maltepe Med J 2019; 9(2): 39–43.
3. Gupta M, Gupta S, Gupta VB. Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. J Thyroid Res. 2010;2010:379051.
4. Ugurluoglu C, Dobur F, Karabagli P, Celik ZE. Fine needle aspiration biopsy of thyroid nodules: cytologic and histopathologic correlation of 1096 patients. Int J Clin Exp Pathol 2015; 8(11): 14800–5.
5. Muratli A, Erdogan N, Sevim S, Unal I, Akyuz S. Diagnostic efficacy and importance of fine-needle aspiration cytology of thyroid nodules. J Cytol 2014; 31(2): 73–78.
6. Imamoglu C, Imamoglu FG, Dizen H, Argon A, Adıbelli ZH. Ultrasound guided fine needle aspiration cytology in thyroid nodules: Cytohistologic correlation. Mugla Sitki Kocman Uni Med J 2015; 2(3): 7–11.
7. Alolayan H, Alyahya Y, Altuaysi A, Alshammari F, Alsakran B. Accuracy of fine needle aspiration cytology of thyroid compared to final histopathology in total thyroidectomy. Int J Med Developing Countries 2020; 4(1): 179–84.
8. Gul K, Ersoy R, Dirikoc A, Korukluoglu B, Ersoy PE, Aydin R, et al. Ultrasonographic evaluation of thyroid nodules: comparison of ultrasonographic, cytological, and histopathological findings. Endocrine 2009; 36(3): 464–72.
9. Ozdemir D, Ersoy R, Cuhaci N, Arpaci D, Ersoy EP, Korukluoglu B, et al. Classical and follicular variant papillary thyroid carcinoma: Comparison of clinical, ultrasonographical, cytological, and histopathological features in 444 patients. Endocr Pathol 2011; 22(2): 58–65.
10. Haberal AN, Toru S, Ozen O, Arat Z, Bilezikçi B. Diagnostic pitfalls in the evaluation of fine needle aspiration cytology of the thyroid: correlation with histopathology in 260 cases. Cytopathology 2009; 20(2): 103–8.
11. Cibas ES, Ali SZ. The 2017 Bethesda system for reporting thyroid cytopathology. Thyroid 2017; 27(11): 1341–6.
12. Anand B, Ramdas A, Ambroise MM, Kumar NP. The bethesda system for reporting thyroid cytopathology: A cytohistological study. J Thyroid Res 2020; 2020: 8095378.
13. Zhu Y, Song Y, Xu G, Fan Z, Ren W. Causes of misdiagnoses by thyroid fine-needle aspiration cytology (FNAC): our experience and a systematic review. Diagn Pathol 2020; 15(1): 1.
14. R Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria, 2021. Available from: URL: https://www.R-project.org/. Accessed Jan 30, 2023.
15. Wu HH, Jones JN, Osman J. Fine-needle aspiration cytology of the thyroid: ten years experience in a community teaching hospital. Diagn Cytopathol 2006; 34(2): 93–6.
16. Sangalli G, Serio G, Zampatti C, Bellotti M, Lomuscio G. Fine needle aspiration cytology of the thyroid: a comparison of 5469 cytological and final histological diagnoses. Cytopathology 2006; 17(5): 245–50.
17. Masereka R, Okeny PK, Fualal JO, Wamala D. Diagnostic accuracy of fine needle aspiration cytology in patients undergoing thyroidectomy in Uganda: tertiary hospital experience. Afr Health Sci 2016; 16(4): 1143–50.
18. Bohacek L, Milas M, Mitchell J, Siperstein A, Berber E. Diagnostic accuracy of surgeon-performed ultrasound-guided fine-needle aspiration of thyroid nodules. Ann Surg Oncol 2012; 19(1): 45–51.
19. Handa U, Garg S, Mohan H, Nagarkar N. Role of fine needle aspiration cytology in diagnosis and -management of thyroid lesions: A study on 434 patients. J Cytol 2008; 25(1): 13–7.
20. Dincer N, Balci S, Yazgan A, Guney G, Ersoy R, Cakir B, et al. Follow- up of atypia and follicular lesions of undetermined significance in thyroid fine needle aspiration cytology. Cytopathology 2013; 24(6): 385–90.
21. Hemmati HR, Shahnazari B, Foroutan M. The Effect of Fine needle aspiration on Detecting Malignancy in Thyroid Nodule. Biomol Concepts 2019; 10(1): 99–105.

APA	ERDOĞAN DÜZCÜ S, Tunç Karabekiroğlu N, astarcı h, KAYIS S (2023). Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. , 182 - 189. 10.14744/etd.2023.57267
Chicago	ERDOĞAN DÜZCÜ SELMA,Tunç Karabekiroğlu Nur,astarcı hesna müzeyyen,KAYIS Seyit Ali Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. (2023): 182 - 189. 10.14744/etd.2023.57267
MLA	ERDOĞAN DÜZCÜ SELMA,Tunç Karabekiroğlu Nur,astarcı hesna müzeyyen,KAYIS Seyit Ali Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. , 2023, ss.182 - 189. 10.14744/etd.2023.57267
AMA	ERDOĞAN DÜZCÜ S,Tunç Karabekiroğlu N,astarcı h,KAYIS S Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. . 2023; 182 - 189. 10.14744/etd.2023.57267
Vancouver	ERDOĞAN DÜZCÜ S,Tunç Karabekiroğlu N,astarcı h,KAYIS S Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. . 2023; 182 - 189. 10.14744/etd.2023.57267
IEEE	ERDOĞAN DÜZCÜ S,Tunç Karabekiroğlu N,astarcı h,KAYIS S "Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience." , ss.182 - 189, 2023. 10.14744/etd.2023.57267
ISNAD	ERDOĞAN DÜZCÜ, SELMA vd. "Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience". (2023), 182-189. https://doi.org/10.14744/etd.2023.57267

APA	ERDOĞAN DÜZCÜ S, Tunç Karabekiroğlu N, astarcı h, KAYIS S (2023). Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. Erciyes Medical Journal, 45(2), 182 - 189. 10.14744/etd.2023.57267
Chicago	ERDOĞAN DÜZCÜ SELMA,Tunç Karabekiroğlu Nur,astarcı hesna müzeyyen,KAYIS Seyit Ali Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. Erciyes Medical Journal 45, no.2 (2023): 182 - 189. 10.14744/etd.2023.57267
MLA	ERDOĞAN DÜZCÜ SELMA,Tunç Karabekiroğlu Nur,astarcı hesna müzeyyen,KAYIS Seyit Ali Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. Erciyes Medical Journal, vol.45, no.2, 2023, ss.182 - 189. 10.14744/etd.2023.57267
AMA	ERDOĞAN DÜZCÜ S,Tunç Karabekiroğlu N,astarcı h,KAYIS S Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. Erciyes Medical Journal. 2023; 45(2): 182 - 189. 10.14744/etd.2023.57267
Vancouver	ERDOĞAN DÜZCÜ S,Tunç Karabekiroğlu N,astarcı h,KAYIS S Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience. Erciyes Medical Journal. 2023; 45(2): 182 - 189. 10.14744/etd.2023.57267
IEEE	ERDOĞAN DÜZCÜ S,Tunç Karabekiroğlu N,astarcı h,KAYIS S "Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience." Erciyes Medical Journal, 45, ss.182 - 189, 2023. 10.14744/etd.2023.57267
ISNAD	ERDOĞAN DÜZCÜ, SELMA vd. "Diagnostic Accuracy of Fine-Needle Aspiration Cytology of Thyroid Nodules and Seven Years of Experience". Erciyes Medical Journal 45/2 (2023), 182-189. https://doi.org/10.14744/etd.2023.57267